Physiologically Based Pharmacokinetic Modeling of Antibiotics in Children: Perspectives on Model-Informed Precision Dosing by Ryota Tanaka, Kei Irie, Tomoyuki Mizuno

“…The appropriate use of antibiotics is crucial and involves selecting an optimal dosing regimen based on pharmacokinetic (PK) and pharmacodynamic (PD) indicators. …”
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Communication in the Mirror of Social Semiotics by N. V. Kazarinova

“…The subject of this article is communicative resources, which are selected by partners from a huge variety of linguistic means, functional styles, rhetorical techniques, and subject activities, and through which a common semantic space between individuals is generated.Methodology and sources. …”
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Architectural design solutions towards healing educational environment for autistic children by Mohammadsalar Hafez, Mojtaba Pourahmadi

“…Sampling in this citation is purposeful-selective through in-depth interviews with a statistical population of 20 architects. …”
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Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

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Precision wings treating skeletal class II in growing patients: a systematic review and meta-analysis by Paulo Mecenas, Renata Travassos da Rosa Moreira Bastos, Nathalia Carolina Fernandes Fagundes, David Normando

“…Abstract Background Skeletal Class II malocclusion, often associated with mandibular deficiency, is commonly treated with functional appliances. Precision Wings are a functional appliance that provides an alternative approach by combining mandibular advancement with dental alignment. …”
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Managing moderate-to-severe paediatric asthma: a scoping review of the efficacy and safety of fluticasone propionate/salmeterol by Sira Nanthapisal, Ana Paula Beltran Moschione Castro, Paulo Marcio Pitrez, Chirag Teli, Abhijith P G

“…Search strategies were developed and refined by authors.Charting methods Selected articles were screened for clinical outcome data (exacerbation reduction, nocturnal awakenings, lung function, symptom control, rescue medication use and safety) and a table of key parameters developed.Results Improvements in asthma outcomes with FP/SAL include reduced risk of asthma-related emergency department visits and hospitalisations, protection against exercise-induced asthma and improvements in measures of lung function. …”
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Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis by Tingting Sun, Yuanyuan Jia, Xiaosheng Dong, Yunlong Chai, Zhenmin Bai, Xiao Hou

“…The objective of this review and meta-analysis is to assess the effectiveness of cupping therapy in patients with CMP.Design Systematic review and meta-analysis.Data sources PubMed, Web of Science, EBSCO, Cochrane Library and CNKI (China National Knowledge Infrastructure) were searched through 20 December 2024.Eligibility criteria for selecting studies We included randomised control trials that compared cupping therapy for patients with CMP on outcomes (ie, pain intensity, functional disability and mental health).Data extraction and synthesis Two independent reviewers used standardised methods to search, screen and code included studies. …”
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PROBLEMS OF FORMATION OF FINANCIAL-INVESTMENT PROJECTION OF A BALANCED SCORECARD IN VALUE-BASED ENTERPRISES OF MINING-METALLURGICAL COMPLEX by S. Faizova, M. Ivanova, S. Sannikova, O. Varyanichenko

“…The criteria of strategic targeting, efficiency and functionality have been defined as key criteria in selecting the BSC metrics. …”
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Harnessing greylag goose optimization for efficient MPPT and seven-level inverter in renewable energy systems by K. Rajaram, R. Kannan

“…Owing to the significant increase in energy consumption, contemporary power systems are transitioning to a new standard characterized by enhanced access to renewable energy sources (RESs). RESs require interfaces to regulate the power generation. …”
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Ageing well in the urban environment: meeting the health and social needs of older Adults - study protocol for a prospective, longitudinal mixed-methods study by Marie Bolster, Abhijit Visaria, David Matchar, Denis Gerstorf, Tillman Schmitz, Benjamin Labohm, Raphael Kohl, Dagmar Haase, Paul Gellert, Angelique Chan, Wolfram J. Herrmann

“…Additionally, three functional tests (cognitive functioning, hand grip strength, and walking speed) are carried out with participants. …”
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A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro by Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Heather McClafferty, Alisha May, Helen Alice Taylor, Michael J Shipston, Nicola Romanò, Lesley M Forrester, Pablo Menendez, Antonella Fidanza

“…A major challenge in the stem cell biology field is the ability to produce fully functional cells from induced pluripotent stem cells (iPSCs) that are a valuable resource for cell therapy, drug screening, and disease modelling. …”
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The Role of Circulating Biomarkers in Patients with Coronary Microvascular Disease by Rossella Quarta, Giovanni Martino, Letizia Rosa Romano, Giovanni Lopes, Francesco Fabio Greco, Carmen Anna Maria Spaccarotella, Ciro Indolfi, Antonio Curcio, Alberto Polimeni

“…Coronary microvascular disease (CMD) comprises a spectrum of conditions characterized by the functional and structural abnormalities of coronary microcirculation, affecting vessels typically smaller than 500 μm. …”
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Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

“…Emerging strategies, such as selective NOX inhibitors, antioxidant therapies, and agents modulating signaling transduction, offer promising avenues for mitigating oxidative injury and improving cardiac function. …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…One-third of the included studies used the leaves of the selected plants. The reviewed studies highlighted neuroprotective activities of the plants, as evidenced by biochemical and behavioral improvements. …”
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Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34+ Cells by Dorian Forte, Daria Sollazzo, Martina Barone, Marisole Allegri, Angela di Martella Orsi, Marco Romano, Barbara Sinigaglia, Giuseppe Auteri, Nicola Vianelli, Michele Cavo, Francesca Palandri, Lucia Catani

“…Taken together, these data indicate that combined proinflammatory stimuli promote distinct in vitro functional activation of neonatal or adult normal HSPCs.…”
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A Study on the Influence Mechanisms of Neighborhood Vitality and the Characteristics of Spatial and Temporal Differentiation in the Urban Fringe Areas of Wuhan City by Yan Long, Siyu Hu, Zhengyuan Lu, Lianghao Cheng, Cairui Zhen, Jingmei Shao, Yuqiao Zheng, Xuehui Zhou, Jin Li, Yudi Lin, Shu Zhang, Yue Wang, Tianyue Luo, Haijuan Zhao, Xuejun Liu

“…This paper quantifies the neighborhood vitality of the fringe areas by the short-stay visitors in the fringe areas and selects the 5D elements of the built environment and social media data from multiple sources to construct the indicator system assessing the neighborhood vitality of the urban fringe areas. …”
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Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy. by Corinne Kostic, Simon Geoffrey Lillico, Sylvain Vincent Crippa, Nicolas Grandchamp, Héloïse Pilet, Stéphanie Philippe, Zen Lu, Tim James King, Jacques Mallet, Chamsy Sarkis, Yvan Arsenijevic, Christopher Bruce Alexander Whitelaw

“…Sixty percent of the piglets were transgenic, with mutant GUCY2D mRNA detected in the retina of all animals tested. Functional impairment of vision was observed among the transgenic pigs at 3 months of age, with a follow-up at 1 year indicating a subsequent slower progression of phenotype. …”
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Recent Advances in Understanding the Keys Factors Influencing Pressurized Liquid Extraction of Secondary Metabolites: A Comprehensive Review by Pauline Donn, Sepidar Seyyedi-Mansour, Franklin Chamorro, Paula Garcia-Oliveira, Javier Echave, Ana Perez-Vazquez, Paula Barciela, Lucia Cassani, Miguel Angel Prieto

“…., phenolic compounds) from botanical sources, with implications spanning across pharmaceuticals, nutraceuticals, and functional foods. …”
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The Effectiveness of Exercise Interventions Supported by Telerehabilitation For Recently Hospitalized Adult Medical Patients: A Systematic Review by Simone Leslie, Junmin Tan, Prudence J. McRae, Shaun P. O'Leary, Julie A. Adsett

“…Methods: Studies were selected if they included an exercise intervention for recently hospitalized adults, delivered by a physiotherapist via videoconference. …”
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Controllable surface carrier type of metal oxide nanocrystals for multifunctional photocatalysis by Han Li, Yingchun Ding, Kaiyi Luo, Qiuping Zhang, Huan Yuan, Shuyan Xu, Ming Xu

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