Regenerative Cartilage Treatment for Focal Chondral Defects in the Knee: Focus on Marrow-Stimulating and Cell-Based Scaffold Approaches by Filippo Migliorini, Francesco Simeone, Tommaso Bardazzi, Michael Kurt Memminger, Gennaro Pipino, Raju Vaishya, Nicola Maffulli

“…Given the limited regenerative capacity of hyaline cartilage, biologically based surgical strategies have emerged to promote tissue repair and restore joint function. This narrative review critically examines current treatment approaches that rely on autologous cell sources and scaffold-supported regeneration. …”
Get full text

Comparative Genomic and Transcriptomic Analysis Provides New Insights into the Aflatoxin B₁ Biodegradability by <i>Kocuria rosea</i> from Deep Sea by Jingying Wang, Jun Nan

“…In addition, this study revealed 1421 differentially expressed genes and 752 upregulated genes between the aflatoxin group and the control group through transcriptome analysis and conducted functional annotation and analysis of functional enrichment. …”
Get full text

Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> by Sang-Yun Lee, Nari Yoon, Neil Patrick Uy, Chung-Ho Choi, Sanghyun Lee

“…Although previous research has identified the presence of bioactive compounds in <i>A. himalaicum</i> extract, suggesting its potential as a medicinal resource, the phytochemical profile of <i>A. himalaicum</i> extract has not been extensively determined. …”
Get full text

Identification and Analysis of Phenolic Compounds in <i>Vaccinium uliginosum</i> L. and Its Lipid-Lowering Activity In Vitro by Ying Zhang, Wenjiang Dong, Manjun Zhao, Jiyue Zhang, Li Li, Yan Ma, Xianjun Meng, Yuehua Wang

“…(VU), rich in polyphenols, is an important wild berry resource primarily distributed in extremely cold regions. …”
Get full text

HEALTHY NUTRITION AS A SYMBIOSIS OF RATIONAL NUTRITION AND PHYSICAL ACTIVITY by L. Telezhenko, P. Bilenkyi

“…Diets should be selected properly to provide a daily rate of various antioxidants. …”
Get full text

CFD investigation and ANN prediction of heat transfer coefficient for fully developed turbulent air flow around double V-baffle turbulators by Abdulaziz Alasiri, H.E. Fawaz

“…The process of training incorporates the analysis of the loss function on training and validation data for controlling the weights and biases using backpropagation while feed forward propagate the selected input parameters. …”
Get full text

GASTROINTESTINAL BLEEDING WITH THE USE OF NEW ORAL ANTICOAGULANTS: EPIDEMIOLOGY, RISK FACTORS, TREATMENT, AND PREVENTION by E. V. Moroz, A. E. Karateev, E. V. Kryukov, V. A. Chernetsov

“…Novel oral anticoagulants (NOACs), such as the direct thrombin inhibitor dabigatran and the selective factor Xa inhibitors rivaroxaban and apixaban, are increasingly used as an effective antithrombotic drug in real clinical practice. …”
Get full text

SIMPLE: Simple Intensity Map Producer for Line Emission by Maja Lujan Niemeyer, José Luis Bernal, Eiichiro Komatsu

“…Simple can be applied to any spectral line sourced by galaxies. The Simple code is based on lognormal mock catalogs of galaxies including positions and velocities and assigns luminosities following the luminosity function. …”
Get full text

REGULATORY INTEGRATION IN THE HEALTHCARE SECTOR OF UKRAINE by Mykhailo D. Diachuk

“…Materials and methods. 20 regulatory and legal documents and 16 scientific literary sources on the topic of the research materials were selected. …”
Get full text

Green Chemistry Method for Analyzing Bisphenol A in Milk by Angela M. Encerrado Manriquez, Wen-Yee Lee

“…A simple, fast, green, and sensitive method for determining Bisphenol A (BPA) levels in commercial milk was developed using a solventless sample preparation technique known as stir bar sorptive extraction, coupled with thermal desorption–gas chromatography/mass spectrometry. BPA was selected due to its ubiquitous presence in the environment and its classification as an endocrine-disrupting chemical of concern (i.e., its ability to mimic hormone functions). …”
Get full text

Identification of mitophagy and ferroptosis-related hub genes associated with intracerebral haemorrhage through bioinformatics analysis by Yan Wang, Rufeng Wang, Jianzhong Zhu, Ling Chen

“…Background Mitophagy and ferroptosis occur in intracerebral haemorrhage (ICH) but our understanding of mitophagy and ferroptosis-related genes remains incomplete.Aim This study aims to identify shared ICH genes for both processes.Methods ICH differentially expressed mitophagy and ferroptosis-related genes (DEMFRGs) were sourced from the GEO database and literature. Enrichment analysis elucidated functions. …”
Get full text

Live and heat-killed Leuconostoc mesenteroides counteract the gastrointestinal dysfunction in chronic kidney disease mice through intestinal environment modulation. by Fittree Hayeeawaema, Natthawan Sermwittayawong, Chittipong Tipbunjong, Nawiya Huipao, Paradorn Muangnil, Pissared Khuituan

“…This study aimed to evaluate the probiotic potential of lactic acid bacteria derived from natural sources and to investigate the effects of both live and heat-killed Leuconostoc mesenteroides (Ln.m) on renal and gastrointestinal functions in CKD mice. …”
Get full text

Robustness of viral load over CD4 cell count in measuring the quality of life of people with HIV at second line regimen in Amhara region by Awoke Seyoum Tegegne

“…Monitoring the quality of life of people under treatment helps to optimize the resource allocated for the program. Therefore, the main objective of the current study was to assess the quality of life comparing viral load and CD4 cell count and factors affecting the variable of interest among HIV-positive people under the second-line regimens. …”
Get full text

Transcriptome analysis reveals common and distinct mechanisms for sheepgrass (Leymus chinensis) responses to defoliation compared to mechanical wounding. by Shuangyan Chen, Yueyue Cai, Lexin Zhang, Xueqing Yan, Liqin Cheng, Dongmei Qi, Qingyuan Zhou, Xiaoxia Li, Gongshe Liu

“…Additionally, the distinct DEGs represent a valuable resource for novel gene discovery that may improve plant resistance to defoliation from various processes.…”
Get full text

A methodology for quantitatively managing the bug fixing process using Mahalanobis Taguchi system by Boby John, R. S. Kadadevarmath

“…The controlling of bug fixing process during the system testing phase of software development life cycle is very important for fixing all the detected bugs within the scheduled time. The presence of open bugs often delays the release of the software or result in releasing the software with compromised functionalities. …”
Get full text

New strategies and advancements in the synthesis of metal organic frameworks for PAHs removal by Cong Thanh Nguyen, Edgar N. Tec-Caamal, Arunadevi Natarajan, Nguyen Chi Thanh

“…Globally, the increased urbanization and industrialization lead to a lack of resources and the discharge of harmful/toxic chemicals like polyaromatic hydrocarbons (PAHs) into the environment. …”
Get full text

Construction of an Ecological Security Structure in Fuzhou City of Jiangxi Provicne Based on an MCR Model by Chen Qun, Liu Pinghui, Zhu Chuanmin

“…A minimum cumulative resistance (MCR) model was constructed by selecting various land use factors, soil and water conservation function importance, and ecological sensitivity. …”
Get full text

Metagenomic analysis reveals methanogenic and other archaeal genes in the digestive tract of invasive Japanese beetle larvae and associated soil by Helena Avila-Arias, Michael E. Scharf, Ronald F. Turco, Diego J. Jiménez, Audrey Simard, Douglas S. Richmond

“…The presence of the same archaeal features in both soil and JB midgut suggests that the JB midgut archaeome may be environmentally sourced, with more tailored selection of the archaeome occurring in the JB hindgut. …”
Get full text

Harnessing polydiacetylene (PDA): A review of structural mechanics and infectious disease detection by Soumendu Patra, Harshita Shand, Sayan Ghosal, Suvankar Ghorai

“…These biosensors can also be functionalized with particular capture agents, such as antibodies or nucleic acid probes, to selectively bind and detect the target analytes. …”
Get full text

The therapeutic validity and effectiveness of physiotherapeutic exercise following total hip arthroplasty for osteoarthritis: A systematic review. by Annet Wijnen, Sjoukje E Bouma, Gesine H Seeber, Lucas H V van der Woude, Sjoerd K Bulstra, Djordje Lazovic, Martin Stevens, Inge van den Akker-Scheek

“…Characteristics of the physiotherapeutic exercise interventions and results about joint and muscle function, functional performance and self-reported outcomes were extracted.…”
Get full text