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1961
Evaluation of the effect of irrigation with purified wastewater on the physical and chemical properties of soil
Published 2019-06-01“…Also, the growth rate of the organs as a function of the treatment conditions during the experiment had a significant difference. …”
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1962
The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021
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1963
Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di...
Published 2020-03-01“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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1964
Medicinal plants with neuroprotective potential in East African countries: A systematic review
Published 2025-02-01“…One-third of the included studies used the leaves of the selected plants. The reviewed studies highlighted neuroprotective activities of the plants, as evidenced by biochemical and behavioral improvements. …”
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1965
Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema
Published 2023-02-01“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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1966
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1967
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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1968
Canopy Transpiration Mapping in an Apple Orchard Using High-Resolution Airborne Spectral and Thermal Imagery with Weather Data
Published 2025-05-01“…In addition, weather information for estimating ET is very often selected from sources that do not represent conditions like heterogeneous site-specific conditions. …”
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1969
Accelerated low-intensity rTMS does not rescue anxiety behaviour or abnormal connectivity in young adult rats following chronic restraint stress
Published 2022-09-01“…Behaviour was assessed using the Elevated Plus Maze and Forced Swim Test, and functional, chemical, and structural brain changes measured using magnetic resonance imaging techniques. …”
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1970
A competing risk analysis of predictors of time to lost to follow-up among adults with TB/HIV coinfection in Bahir Dar
Published 2025-08-01“…Overestimating effect sizes when considering mutually exclusive events, like LTFU from ART and anti-TB treatment, can occur if sources of error are not properly accounted for in competing events. …”
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1971
A Systematic Review of risk factors for major adverse cardiovascular events in patients with coronary heart disease who underwent percutaneous coronary intervention
Published 2025-04-01“…ObjectiveThis study aims to systematically review the risk factors for major adverse cardiovascular events (MACE) in patients with coronary heart disease who have undergone percutaneous coronary intervention (PCI).DesignSystematic review and meta-analysis.Data sourcesThe Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals (VIP) were screened until December 2024.Eligibility criteria for selecting studiesCase-control studies or cohort studies on the risk factors for MACE in patients with coronary heart disease who underwent PCI. …”
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1972
A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o...
Published 2013-03-01“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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1973
Whole blood RNA-seq analysis reveals the immunomodulatory effects of a supplemental multi-strain direct-fed microbial in the diet of newly weaned beef steers1
Published 2025-07-01“…On day 56, 10 mL of blood was collected from 10 randomly selected beef steers from each treatment group prior to morning feeding. …”
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1974
Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda.
Published 2021-01-01“…Data were analysed descriptively and a binomial generalised linear model with a log link function used to investigate factors associated with unwillingness to participate.…”
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1975
Persistence in the socio-economic development of the regions of the Siberian Federal District
Published 2024-01-01“…The term «persistence» originally has a biological and medical origin, as a property of microorganisms (bacteria, viruses) to survive and function in an aggressive environment (e.g., when exposed to antibiotics). …”
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1976
Glucosylceramides containing very long-acyl-chain fatty acid are critical for cotton fiber elongation by influencing brassinosteroid synthesis and signaling
Published 2025-08-01“…Cotton fiber is one of the longest plant cells and sphingolipids are closely associated with the development of cotton fiber cells. However, their function in cotton fiber cell development and its action mechanism is unclear. …”
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1977
Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment
Published 2025-06-01“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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1978
Life cycle assessment of an entirely wood floor system designed for carbon negativity, future adaptability, and end-of-life de/re/construction
Published 2025-01-01“…Mass timber offers a promising alternative, with lower embodied carbon (EC) and the potential to function as a carbon sink when sustainably sourced. …”
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1979
Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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1980
Path to Heritagization in Landscape Architecture: A Review of the Regeneration Design of Beijing Changchunyuan Park
Published 2025-03-01“…Undoubtedly, Changchunyuan Park adjacent to Changchun Temple is inherently bearing the same responsibility for cultural transmission. 2) Style and form selection: The traditional Beijing garden style is taken as the tone of “named composition” to regain the contemporary significance of traditional classic space. …”
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