Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
Get full text

GWAS and WGCNA analysis uncover candidate genes associated with drought in Brassica juncea L. by Yusong Zhang, Yusong Zhang, Xiaoyan Yuan, Xiaoyan Yuan, Yunyun Zhang, Yunyun Zhang, Yanqing Luo, Yanqing Luo, Kaiqin Zhao, Kaiqin Zhao, Feng Zu, Feng Zu, Zhengshu Tian, Zhengshu Tian, Jinfeng Li, Jinfeng Li, Lifan Zhang, Lifan Zhang, Xiaoying He, Xiaoying He, Jinxiang Gao, Jinxiang Gao, Minglian Fu, Minglian Fu, Genze Li, Genze Li, Feihu Liu

“…To screen drought-tolerant germplasm resources and key functional genes related to drought tolerance in Brassica juncea L.(193 accessions), three treatments were applied at the germination and seedling stages:control(CK), moderate drought stress (M), and severe drought stress (S). …”
Get full text

Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation by Hongyan Xu, Hongyan Xu, Guocai Han, Yanyan Li, Qing Meng, Qing Meng, Yang Zhang, Yayi Wang, Songling Li

Get full text

Barriers to and facilitators of rehabilitation according to socio-economic status, after acute respiratory distress syndrome due to COVID-19: A qualitative study in the RECOVIDS co... by Mathilde Kléber, Nicolas Meunier-Beillard, Isabelle Fournel, Eléa Ksiazek, Marine Jacquier, Fiona Ecarnot, Jean-Philippe Rigaud, Pierre-Louis Declerq, Jean-Pierre Quenot, Marie Labruyère

“…<h4>Background</h4>The COVID-19 pandemic may have compounded social disparities in access to healthcare, with possible deleterious consequences on the functional prognosis of patients after a stay in the intensive care unit (ICU). …”
Get full text

Mortalin overexpression predicts poor prognosis in early stage of non–small cell lung cancer by Jie Sun, Shuan-Long Che, Jun-Jie Piao, Ming Xu, Li-Yan Chen, Zhen-Hua Lin

Get full text

Metallosphaera sedula bifurcates into two sizes when it is cultured mixotrophically on soluble iron by Robert C. Blake, Richard G. Painter, Nghi Pham, Olivia Griswold, Brooke White, Richard A. White, Richard A. White, Richard A. White

“…Metallosphaera sedula is a thermoacidophilic archaeon that obtains all of its energy for growth from aerobic respiration and oxidative phosphorylation at the expense of selected organic and inorganic sources of electrons. …”
Get full text

Framework for early assessment of food safety hazards in the transition to a more sustainable food system: three case studies in the Vietnamese Mekong Delta by Rosa A. Safitri, Lianne M.S. Bouwman, Marianna Siegmund-Schultze, Tri Minh Nhan, Mohammed Ariful Islam, Esther D. van Asselt, Katja C.W. van Dongen

“…This study applied a qualitative framework to investigate changes in the occurrence of food safety hazards resulting from adopting adaptation strategies at primary production. We selected three case studies (CS) in the VMD: (1) adaptation in the usage and application of water sources for agricultural production, (2) shifting from monoculture rice, duck, and fish to an integrated crop-livestock farming, and (3) introduction of a new crop (i.e., quinoa). …”
Get full text

Personality and Personality Disorders in Medication-Overuse Headache: A Controlled Study by SWAP-200 by Federica Galli, Annalisa Tanzilli, Alessandra Simonelli, Cristina Tassorelli, Grazia Sances, Micol Parolin, Patrizia Cristofalo, Ivan Gualco, Vittorio Lingiardi

“…At levels of specific PDs, MOH patients showed higher obsessive and dysphoric traits and better overall psychological functioning than SUD and PD patients. Conclusion. Although MOH, SUD, and PD populations have been evaluated in multiple sites with different levels of expertise, the study supported the presence of a specific constellation of personality in MOH patients including obsessive (perfectionist) and dysphoric characteristics, as well as good enough psychological resources. …”
Get full text

Exploring Autophagy-Related Gene Expression in Hepatocellular Carcinoma via TCGA, GEPIA2, and HPA Databases: Implications for Prognosis by Gu X, Chen Y, Hu X, Li Y, Zhu R, Li H, Yuan Z, Wang Y

“…RT-qPCR analysis further confirmed significant upregulation of mRNA expression levels of randomly selected BAG3, EIF2AK2, KIF5B, and RAB24 in HCC cell lines, consistent with the bioinformatics analysis findings.Conclusion: This study showed that the 41 obtained ARGs, such as ATG16L1, ATG4B, BAG3, KIF5B, MAPK1, RAB24, and SOGA1, these findings suggest that ARGs may serve as prognostic biomarkers for HCC, warranting further validation in clinical cohorts and functional studies.Keywords: hepatocellular carcinoma, bioinformatics, autophagy, prognostic markers, TCGA…”
Get full text

The accuracy of a novel stunting risk detection application based on nutrition and sanitation indicators in children aged under five years by Tria Astika Endah Permatasari, Yudi Chadirin, Ernirita Ernirita, Anisa Nurul Syafitri, Devina Alifia Fadhilah

“…Methods This cross-sectional study was conducted between June and September 2023 and involved 316 mother-child pairs selected by simple random sampling from urban (n = 244) and rural (n = 72) areas in Bogor, West Java Province, Indonesia. …”
Get full text

A comparative assessment of WASH adherence among public and private school students in a rural district in Nigeria by Ayoola O. Bosede, Rejoice C. Enwenonu, Justina U. Udensi, Onyenonachi C. Ihejirika, Kolawole C. Akindulureni, Onyima C. Emenonu, Thelma C. Mezieobi

“…A multi-stage sampling technique was used to select 20 secondary schools, with a total of 400 students participating in the study. …”
Get full text

Expressing the Author's Position in the English-Language Network Film Review by I. V. Kononova, T. A. Klepikova, E. A. Klenova

“…The authors proceed from the position that the methods of subject verbalization are determined by functional characteristics of discourse. The relevance of the study is due to the interest of modern linguistics in the study of the subject factor in “personal” types of discourse. …”
Get full text

The Internationalization of Science and Education as a Global Process: a World-System Approach by A. A. Izgarskaya, S. I. Chernykh

“…Today, there is a need to select theoretical and methodological grounds for explaining the problems that have arisen in Russian science and the educational system in the process of internationalization. …”
Get full text

Biomimetic Design Concepts in African Textile Prints: Embracing Nature's Influence on Fashion and Textiles by Frederick Boamah, Benjamin Tawiah, Ebenezer Howard

“…Eight seed articles were identified after which bibliography coupling was done to identify important articles worthy of inclusion based on the main terms in the topic. The co-citation functionality in Google Scholar was used to further identify and select recent articles that meet the inclusion criteria set out. …”
Get full text

Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data. by Jyotsna Batra, Felicity Lose, Tracy O'Mara, Louise Marquart, Carson Stephens, Kimberly Alexander, Srilakshmi Srinivasan, Rosalind A Eeles, Douglas F Easton, Ali Amin Al Olama, Zsofia Kote-Jarai, Michelle Guy, Kenneth Muir, Artitaya Lophatananon, Aneela A Rahman, David E Neal, Freddie C Hamdy, Jenny L Donovan, Suzanne Chambers, Robert A Gardiner, Joanne Aitken, John Yaxley, Mary-Anne Kedda, Judith A Clements, Amanda B Spurdle

“…METHODS AND DATA SOURCES: Twelve out of 22 SNPs, selected on the basis of linkage disequilibrium pattern, were analyzed in an Australian sample of 1,011 histologically verified prostate cancer cases and 1,405 ethnically matched controls. …”
Get full text

Predicting the course of localized periodontitis of traumatic etiology after complex treatment by Aleksandra V. Smirnova, Diana A. Kuzmina, Natalia A. Sokolovich, Ekaterina S. Mikhailova, Svetlana V. Sverdlova, Ivan V. Grigoriev

“…To assess the body’s adaptive resources, the entropy of the leukocyte blood count was calculated, and risk factors for the occurrence of LPT were assessed. …”
Get full text

Impacts of Mechanical Injury on Volatile Emission Rate and Composition in 45 Subtropical Woody Broad-Leaved Storage and Non-Storage Emitters by Yali Yuan, Yimiao Mao, Hao Yuan, Ming Guo, Guomo Zhou, Ülo Niinemets, Zhihong Sun

Get full text

Development and Optimization of a Novel Deep Learning Model for Diagnosis of Quince Leaf Diseases by A. Naderi Beni, H. Bagherpour, J. Amiri Parian

“…Of all the images obtained, 70%, 20%, and 10% were randomly selected for the network's training, validation, and testing, respectively. …”
Get full text

Fe foam supported FeVO4 nanoparticles for electrochemical nitrogen fixation at ambient conditions by Abdulmalik Aminu, Bilal Masood Pirzada, Shamraiz Hussain Talib, Janah Shaya, Ibrahim Yildiz, Sharmarke Mohamed, Ahsanulhaq Qurashi

“…Furthermore, the coupling interaction between FeVO4 and FF support exposed abundant intrinsic active sites and facilitated beneficial charge transfer further inducing superior e-NRR activity. Density functional theory (DFT) computations disclosed that surface Fe atoms are the main active centers for e-NRR which proceed via the alternating pathway.…”
Get full text

Smart Fault Detection, Classification, and Localization in Distribution Networks: AI-Driven Approaches and Emerging Technologies by Jianxian Wang, Hazlie Mokhlis, Nurulafiqah Nadzirah Mansor, Hazlee Azil Illias, Agileswari K. Ramasamy, Xingyu Wu, Siqi Wang

“…The insights offered herein are expected to provide practical guidance for engineers and researchers for selecting and deploying intelligent fault diagnosis strategies in future distribution networks with high distributed generation penetration.…”
Get full text