Comparing soil microbial diversity in smallholder plantain backyard gardens and main farms in Western and Central Africa by Manoj Kaushal, Yao Adjiguita Kolombia, Amos Emitati Alakonya, Cargele Masso

“…Beneficial genera such as Bacillus, Streptomyces, Bradyrhizobium, and Paenibacillus were also detected. Functional predictions based on COG and KEGG databases indicated notable differences in microbial functional potential between the two settings. …”
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Integrated microbiome and metabolome approaches reveal the resistant mechanisms of leaf blight resistant plum cultivar by Xinyan Zhou, Yufei Wei, Yu Zhu, Jiaoming Li, Runche Zhou, Qingju Xiao, Ruihong Luo, Shangdong Yang

“…Results The results showed that higher microbial diversity and richness could be detected in RP cultivar than those of SP cultivar. …”
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Metagenome Analysis Identified Novel Microbial Diversity of Sandy Soils Surrounded by Natural Lakes and Artificial Water Points in King Salman Bin Abdulaziz Royal Natural Reserve,... by Yahya S. Al-Awthan, Rashid Mir, Fuad A. Alatawi, Abdulaziz S. Alatawi, Fahad M. Almutairi, Tamer Khafaga, Wael M. Shohdi, Amal M. Fakhry, Basmah M. Alharbi

“…Results: In this study, sandy soil samples from the surroundings of natural and artificial water resources of two distinct natures were used. Based on 16S rRNA sequencing, a total of 24,563 OTUs were detected. …”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Abstract Background HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. …”
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Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…The objectives of this work were to deepen the understanding of the regulation of the function of taste receptor genes in the circumvallate papillae of obese Iberian pigs in comparison to Duroc pigs, and to characterize their genetic variation and associations with relevant production traits. …”
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Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice by Tetsushi Kagawa, Yuhei Yamaguchi, Yasuhiro Kokubu, Genki Sudo, Aoi Ebisawa, Satoko Hattori, Keizo Takao, Kohtarou Konno, Naomi Nakagata, Takafumi Inoue, Masahiko Watanabe, Johji Inazawa, Tsuyoshi Miyakawa, Tetsuya Taga

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Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease. by Masayuki Fukumoto, Daisuke Miyamoto, Akihiko Soyama, Takanobu Hara, Yasuhiro Maruya, Peilin Li, Hajime Matsushima, Kazushige Migita, Takahiro Enjoji, Hanako Tetsuo, Takuro Fujita, Mampei Yamashita, Hajime Imamura, Tomohiko Adachi, Kengo Kanetaka, Takahiro Ochiya, Susumu Eguchi

“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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Bioactive matters based on natural product for cardiovascular diseases by Linfang Zhong, Xiaoying Tan, Wenhui Yang, Peishan Li, Lianbao Ye, Qi Luo, Honghao Hou

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Energy filtering enables macromolecular MicroED data at sub-atomic resolution by Max T. B. Clabbers, Johan Hattne, Michael W. Martynowycz, Tamir Gonen

“…While direct electron detection essentially eliminates the read-out noise during MicroED data collection, other sources of noise remain and limit the measurement of faint high-resolution reflections. …”
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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…However, the stiffness heterogeneity of TME within PDAC functions on tumor cell stem-like phenotypes remains unclear. …”
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Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

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Optimizing maize germination forecasts with random forest and data fusion techniques by Lili Wu, Yuqing Xing, Kaiwen Yang, Wenqiang Li, Guangyue Ren, Debang Zhang, Huiping Fan

“…Traditional methods for detecting seed germination rates often involve lengthy experiments that result in damaged seeds. …”
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Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period by Yingyu He, Yiquan Zhang, Wanbing Liu, Lidong Zhang, Yingkai Xu, Zihan Yuan, Junying Li, Lei Liu, Fangxiong Cheng

“…On each testing day, storage lesion related indicators of red blood cells (RBCs), plasma components, and platelets were respectively detected.ResultsOn the 14th day of CS-WB storage, no significant changes were found in the morphology, quantity, and function of RBCs. …”
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Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours by Tobias Åkerström, Branislav Klimàcek, Matilda Annebäck, Olov Norlén, Peter Stålberg

“…Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. …”
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Antioxidant Profiling of Botryocladia leptopoda Based on In Silico and In Vitro Studies by Fenny Crista Anastasia Panjaitan, Huey-Jine Chai

“…Thus, B. leptopoda can be considered a promising source of antioxidative products in the functional food and pharmaceutical industries.…”
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Chronic Stress protection for postnatal dEpREssioN prEvention (SERENE): a protocol for an exploratory study by Frederic Dutheil, Dahlia Tharwat, Marion Trousselard, Mélanie Balès, Anne-Laure Sutter-Dallay, Dominique Fromage, Elisabeth Spitz, Dominique Dallay, Thierry Harvey, Eric Welter, Frédéric Coatleven, Lydie Cherier, Frédérique Teissèdre, Jean-Luc Pouly, Anaïs M Duffaud

“…This psychological resource is linked to protective and resilient psychic functioning. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Advanced Microgrid Protection Utilizing Zero Sequence Components With Hard-Ware-in-the-Loop Testing by Zahra Ghanem, Feras Alasali, Naser El-Naily, Hassen Loukil, Haytham Y. Mustafa, Saad M. Saad, Abdelaziz Salah Saidi, William Holderbaum

“…Secondly, the study demonstrates the use of Configurable Function Blocks (CFCs) in digital relays to dynamically adjust relay settings based on zero sequence current detection. …”
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