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3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay
Published 2025-10-01“…Cancer stem cells (CSCs), the primary source of therapy resistance in pancreatic ductal adenocarcinoma (PDAC), exist in a dynamic equilibrium through tumor microenvironment (TME)-driven plasticity. …”
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1322
Validation of a 60K SNP chip for caribou (Rangifer tarandus) for use in wildlife forensics, conservation, and management
Published 2024-12-01“…The SNP chip was shown to be robust, highly sensitive, reliable, and accurate at more than 10-fold below the recommended DNA input. Biological source of DNA had minor impact, even with fecal pellets given sufficient amount of host DNA. …”
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1323
Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake
Published 2025-01-01Get full text
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1324
Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad...
Published 2012-09-01“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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1325
Genetic diversity in wild species and cultivars of strawberry for the <i>FanAAMT</i> gene controlling fruit flavor volatiles
Published 2021-07-01“…‘Karmen’, ‘Ostara’, ‘Samson’, ‘Symphony’, ‘Troubadour’ and ‘Vima Tarda’, in which the functional allele of the FanAAMT gene was found. In the remaining studied strawberry genotypes the marker FanAAMT was not detected, which presumably indicates that the FanAAMT gene is absent. cells (R9.4.1).…”
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1326
State immunological reactivity and autonomic regulation in patients with chronic apical periodontitis
Published 2020-04-01“…In this paper we studied 107 people with a diagnosis of «chronic apical periodontitis». The functional state of the autonomic nervous system were detected by electrophoresis dosed adrenaline and carbachol and test dermographism. …”
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1327
Mobile phone encryption as an obstacle in criminal investigation: Review of comparative solutions
Published 2021-01-01“…In detecting criminal offences, the police increasingly rely on electronic evidence. …”
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1328
Conditions for the emergence of circumnutations in plant roots.
Published 2021-01-01“…Here we describe a model capable of replicating root growth behaviors, which we used to analyze the role of circumnuntations, revealing their emergence I) under gravitropic stress, as a combination of signal propagation and sensitivity to the signal carriers; II) as a result of the interplay between gravitropic and thigmotropic responses; and III) as a behavioral strategy to detect and react to resource gradients. The latter function requires the presence of a hypothetical internal oscillator whose parameters are regulated by the perception of environmental resources.…”
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1329
Chromosome-level genome assembly of starry flounder (Platichthys stellatus)
Published 2025-07-01“…Approximately 94.02% of assembled sequences were anchored into 24 pseudochromosomes, and a total of 18 telomeres were detected. Totally 22,835 protein-coding genes and 227.87 Mb repetitive sequences were identified. …”
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1330
Bovine PMN responses to extracellular vesicles released by Besnoitia besnoiti tachyzoites and B. besnoiti-infected host cells
Published 2024-12-01“…Therefore, we tested whether exposure of bovine PMN to EVs from different cellular sources affects classical PMN effector functions and cytokine/chemokine secretion. …”
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1331
A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6
Published 2025-01-01“…We identify eight DSFGs in seven fields at z = 4–6 through the detection of H α or [O iii ] λ 5008 lines, including fainter lines such as H β , [O iii ] λ 4960, [N ii ] λ 6585, and [S ii ] λλ 6718,6733 for six sources. …”
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1332
Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons
Published 2025-07-01“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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1333
Reconstruction of defects in elastic bodies by combination of genetic algorithm and finite element method
Published 2016-06-01“…The inverse problem solution is based on the minimization of the residual functional between the measured input source information and the data calculated during the numerical solution of direct problems with the given parameters of defects. …”
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1334
Rapid parameter estimation for merging massive black hole binaries using continuous normalizing flows
Published 2024-01-01“…The fast and accurate parameter estimation of merging MBHBs is of great significance for the global fitting of all resolvable sources, as well as the astrophysical interpretation of gravitational wave signals. …”
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1335
Identification method of roof rock interface based on response characteristics of drilling parameters
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1336
Epidemic preparedness and response capacity against infectious disease outbreaks in 186 countries, 2018–2022
Published 2024-11-01“…From the 2022 submissions, 116 (62%) countries reported functional (Level 4 or 5) prevention capacity, 162 (87%) had functional detection capacity, 118 (63%) had functional response capacity, 121 (65%) had functional enabling resources and coordination capacity, and 133 (72%) had functional operational readiness against public health events. …”
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1337
Performance of the HAWC Observatory and TeV Gamma-Ray Measurements of the Crab Nebula with Improved Extensive Air Shower Reconstruction Algorithms
Published 2024-01-01“…Thanks to these improvements, HAWC can now detect more sources, including the Galactic center.…”
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1338
Study of Complex Impedance Dispersion Model for Two-Phase Laminar Flow
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1339
JWST/NIRCam Narrowband Survey of Paβ Emitters in the Spiderweb Protocluster at z = 2.16
Published 2024-01-01“…The weight-corrected color–magnitude diagram obtained 57 sources showing narrowband excesses, 41 of which satisfy further color selection criteria for limiting the sample to Pa β emitter candidates at z ∼ 2.16, and 24 of them do not have H α emitter counterparts. …”
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1340
Unravelling the Impact of an Additional Sex Chromosome in an Adult Female
Published 2023-04-01“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
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