Oxidative Stress Markers and C-Reactive Protein Are Related to Severity of Heart Failure in Patients with Dilated Cardiomyopathy by Celina Wojciechowska, Ewa Romuk, Andrzej Tomasik, Bronisława Skrzep-Poloczek, Ewa Nowalany-Kozielska, Ewa Birkner, Wojciech Jacheć

“…Increased MnSOD activity indicates the mitochondrial source of ROS in patients with advanced heart failure.…”
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Enhancing Medium-Chain Fatty Acid Delivery Through Bigel Technology by Manuela Machado, Eduardo M. Costa, Sara Silva, Sérgio C. Sousa, Ana Maria Gomes, Manuela Pintado

“…This study presents the development and characterization of medium-chain fatty acid (MCFA)-loaded bigels, using coconut oil as the MCFA source. The bigels exhibited high oil binding capacity, ranging from 87% to 98%, effectively retaining MCFAs within the matrix, with lauric acid (C12) being the main component detected within the bigels at 178.32 ± 0.10 mg/g. …”
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Application of microscopic smartphone attachment for remote preoperative lab testing by Kefan Song, Kefan Song, Alexander T. Adams, Alexander T. Adams

“…This device is designed to assist both healthcare providers in resource-limited settings and patients by offering a low-cost, portable diagnostic tool that enables both in-clinic and at-home testing.MethodsThe system was tested for adaptability and compatibility by transitioning from its original Android platform to an iOS platform. …”
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Exploring the Medicinal Potential of <i>Taraxacum Kok-Saghyz</i> (<i>TKS</i>) Using Widely Targeted Metabolomics by Michele Tan, Jeffrey Shih-Chieh Chu, Daniel Robin Swiger

“…This study presents the first comprehensive metabolic profile of <i>TKS</i>, highlighting its potential value beyond rubber production. The detection of numerous therapeutic secondary metabolites supports its promise as a pharmaceutical and nutraceutical resource. …”
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Effects of Covid-19 Pandemic on School Dropout in Selected Primry Schools in Nyarusiza Sub-County Kisoro District. by Sibo, Dusabe Chris Jackson

“…Innovative approaches could be used such as applications of artificial intelligence in high-risk/high-traffic sites to enhance COVID-19 detection efficiency while protecting medical staff and the general public from cross-infections The government should establish a physical and automated platform for coordination and resource mobilization for support to the poor pupils and the most vulnerable groups affected by COVID-19-related lockdown.…”
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Joint Survey Processing. III. Compact Oddballs in the COSMOS Field—Little Red Dots and Transients by Yu-Heng Lin, Andreas L. Faisst, Ranga-Ram Chary, Anton M. Koekemoer, Joseph Masiero, Daniel Masters, Vihang Mehta, Harry I. Teplitz, Gregory L. Walth, John R. Weaver

“…We present the Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) G800L grism spectroscopy observation of the faint active galactic nuclei (AGN) candidates in the Cosmic Evolution Survey field at redshift of 6 selected by the point-source morphology and the photometry drop-off at 8000 Å. …”
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Effect of PM2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens by Lianlian Zhao, Xiaolin Ding, Li Zhou, Chenchen Song, Taisheng Kang, Yanfeng Xu, Yunpeng Liu, Yunlin Han, Wenjie Zhao, Boxiang Zhang, Dan Xu, Jianguo Guo

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Understanding Mantle Edge Pigmentation Through Comprehensive Transcriptomic Profiling of the Chilean Oyster (<i>Ostrea chilensis</i>) by Camila Godoy-Diaz, Katalina Llanos-Azócar, Gonzalo J. Ruiz-Tagle, Jorge E. Toro, Pablo A. Oyarzún, Juan A. Valdés

“…A total of 935,620,583 paired-end reads were de novo assembled, 50,908 transcripts produced, and a reference transcriptome created with 37.92% GC content and an N50 of 1929 bp. Functional annotation showed a total of 51,315 GO terms, with 21,322 annotations on Biological Process, 14,578 annotations on Molecular Functions, and 15,415 annotations on Cellular Component. …”
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Research note: Harnessing the potential of chicken blastodermal cells as a new frontier in poultry science and biotechnology – Establishment of embryonic stem cells and their diffe... by Małgorzata Duda, Patrycja Maciak, Grzegorz Tylko, Kamil Wartalski, Monika Trzcińska, Marek Romek, Marcin Samiec

“…These findings highlight the potential of B-ESCs as a valuable source for propagating SC-LCs, with implications for regenerative medicine and neural/glial tissue engineering applications. …”
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Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry by Yash Mehta, Dhavalkumar Patel, Iqra Pervaiz, Ulrich Bickel, Abraham Jacob Al-Ahmad

“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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Mitigating malicious denial of wallet attack using attribute reduction with deep learning approach for serverless computing on next generation applications by Amal K. Alkhalifa, Mohammed Aljebreen, Rakan Alanazi, Nazir Ahmad, Sultan Alahmari, Othman Alrusaini, Ali Alqazzaz, Hassan Alkhiri

“…Abstract Denial of Wallet (DoW) attacks are one kind of cyberattack whose goal is to develop and expand the financial sources of a group by causing extreme costs in their serverless computing or cloud environments. …”
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Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study by Tinkara Srnovršnik, Bojana Pinter, Milena Horvat, Janja Snoj Tratnik, Ingrid Falnoga, Darja Mazej, Ivan Verdenik, Irma Virant-Klun

“…This case–control study aimed to determine levels of essential TEs (manganese (Mn), copper (Cu), zinc (Zn), selenium (Se), molybdenum (Mo)) and non-essential TEs (arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb)) in urine, whole blood, and serum to investigate a possible association with kidney and liver function, endocrine and metabolic parameters, and environmental and lifestyle sources of potential exposure and provide possible recommendations. …”
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Potential physiological mechanisms behind variation in rainbow trout (Oncorhynchus mykiss) to biosynthesize EPA and DHA when reared on plant oil replacement feeds by Ken Overturf, Jason Abernathy, Dietmar Kültz, Jacob Bledsoe, Shawn Narum, Thomas Welker

“…The omega-3 fatty acids, docosahexaenoic acid (DHA; 22:6n-3) and eicosapentaenoic acid (EPA; 20:5n-3), are of primary concern as they provide significant health benefits such as reducing inflammation and improving heart and health function. However, the DHA; 22:6n-3 and EPA; 20:5n-3 available for aquaculture feeds is primarily provided by fish oil which is already limited in availability and expensive, and dietary lipids are consistently being replaced with oil sourced from plants. …”
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Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat by Fahad Ali Kazmi, Ülo Mander, Ramita Khanongnuch, Maarja Öpik, Reti Ranniku, Kaido Soosaar, Mohit Masta, Salla A. M. Tenhovirta, Kuno Kasak, Claudine Ah-Peng, Mikk Espenberg

“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
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CoreTIA: a modular, statistically robust transduction inhibition assay for AAV neutralization by Beatrix Kovács, Beatrix Kovács, Beatrix Kovács, Fanni Somogyi, Fanni Somogyi, Viktória Szabó, Zoltán Zsolt Nagy, István Hernádi, Ferenc Mátyás, Wim Vanduffel, Zsuzsanna Szemlaky, Balázs Rózsa, Balázs Rózsa, István Ulbert, István Ulbert, István Ulbert, István Ulbert, Dániel Hillier, Dániel Hillier, Dániel Hillier

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Development of a Novel KCNN4-Related ceRNA Network and Prognostic Model for Renal Clear Cell Carcinoma by Hengtao Bu, Qiang Song, Jiexiu Zhang, Yuang Wei, Bianjiang Liu

“…Finally, quantitative real-time polymerase chain reaction and western blot were conducted for KCNN4 expression detection in cell lines and clinical samples. Small interfering RNA was employed to knock down KCNN4, and corresponding functional experiments were conducted on ccRCC cells as well. …”
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Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases by He Lu, Yaohui Jiang, Rui Luo, Dexing Zhou, Feihu Zheng, Liran Shi, He Zhang, Yong Wang, Xiaodong Xu, Renfang Zou, Yujing Zhou, Shuai Ren, Xiaocheng Wang, Haiqiang Sang

“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
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Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…We recover magnetic field strengths for inflated HJs by applying well-known scaling laws for fast rotators. When strong heat sources are applied mostly in the outer envelope and outside the dynamo region, as realistic ohmic models predict, convection in the dynamo region often breaks down. …”
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Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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