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The cardiac phospho-proteome during pressure overload in mice
Published 2025-08-01“…Our analysis highlights significant changes in hypertrophic signalling, metabolic remodelling, contractile function, and the stress response pathways. We present proteomic data from the main cardiac cell types (endothelial cells, fibroblasts and cardiomyocytes) to reveal the cellular localisation of the detected phospho-proteins, offering insights into temporal and site-specific phosphorylation events, facilitating the potential discovery of novel therapeutic targets and biomarkers. …”
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1622
Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains
Published 2025-06-01“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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1623
Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray
Published 2025-01-01“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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1624
Current status of transcriptome sequencing technology in ruminants
Published 2025-06-01“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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1625
Multimodal Therapeutic Effects of Neural Precursor Cells Derived from Human-Induced Pluripotent Stem Cells through Episomal Plasmid-Based Reprogramming in a Rodent Model of Ischemi...
Published 2020-01-01“…Stem cell therapy is a promising option for treating functional deficits in the stroke-damaged brain. Induced pluripotent stem cells (iPSCs) are attractive sources for cell therapy as they can be efficiently differentiated into neural lineages. …”
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1626
Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh
Published 2024-11-01“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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1627
New Insights on Quality, Safety, Nutritional, and Nutraceutical Properties of Honeydew Honeys from Italy
Published 2025-01-01“…This contribution aims to provide a comprehensive characterization of the physico-chemical, palynological, functional, and food safety properties of a large sampling of honeydew honeys collected throughout Italy. …”
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1628
Origami-Inspired Biosensors: Exploring Diverse Applications and Techniques for Shape-Changing Sensor Platforms
Published 2024-12-01“…Paper and biological substrates like DNA have been integrated with origami techniques to develop biosensors with enhanced functionality. The incorporation of aptamer origami into both paper and DNA biosensors further increases sensitivity and specificity for target detection. …”
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1629
Methodology for the identification of bioactive and marker peptides in the organs of cattle and pigs
Published 2022-07-01“…This category of these food-products is intended for personal ized nutrition of various age groups in the population, taking into account fortification of the food with nutraceuticals and with functional and metabolically active ingredients obtained from animal and vegetable source. …”
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1630
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1631
THE EVALUATION OF CURRENT RESEARCH ON THE STRENGTH OF DENTAL RESTORATIVE COMPOSITE MATERIALS
Published 2022-06-01“… The aim of the study: to analyze the sources of scientific and metric information on the state of research on the strength of dental composites for tooth restoration. …”
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1632
Assessing the Impact of Covid19-Pandemic on the Household Income in Kamuganguzi Sub-County Kabale District.
Published 2024“…Additionally, the government should establish a physical and automated platform for coordination and resource mobilization to support poor students and the most vulnerable groups affected by COVID-19-related lockdowns.…”
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1633
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1634
Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria
Published 2020-01-01“…The electronic medical record (EMR) is a source of clinical information that could identify high-risk populations for LCS, including a diagnosis of COPD; however, an unsubstantiated COPD diagnosis in the EMR may lead to inappropriate LCS referrals. …”
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1635
Performance of the National Tuberculosis Control Program in the post conflict Liberia.
Published 2018-01-01“…For the performance of tuberculosis laboratory testing, all the 107 functional tuberculosis microscopy centers in Liberia were included. …”
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1636
Diagnosing skin neglected tropical diseases with the aid of digital health tools: A scoping review.
Published 2024-10-01“…Recent developments in digital health have given rise to approaches that could increase access to diagnosis in resource-poor areas affected by skin NTDs. This scoping review provides an overview of current digital health approaches that aim to aid in the diagnosis of skin NTDs and provides an insight into the diverse functionalities of current digital health tools, their feasibility, usability, and the current gaps in research around these digital health approaches. …”
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1637
Single-cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes
Published 2024-12-01“…The AOS comprising the peripheral sensory vomeronasal organ has evolved elaborate molecular and cellular mechanisms to detect chemo signals. To gain insight into the cell types, developmental gene expression patterns, and functional differences amongst neurons, we performed single-cell transcriptomics of the mouse vomeronasal sensory epithelium. …”
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1638
Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples
Published 2025-03-01“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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1639
Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (<i>Hippophae rhamnoides</i> L.) Pomace: Chemical Composition and Biological Activities
Published 2025-05-01“…Sea buckthorn pomace (SBP) is a rich source of flavonoid compounds with potential healthy properties. …”
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1640
Characterize the Complete Mitogenome of Semiaquilegia guangxiensis and Assess the Efficiency of the Mitochondrial Genes in Ranunculales Phylogeny
Published 2025-04-01“…Moreover, a large number of repetitive mitogenome sequences and chloroplast‐sourced sequences transferred to the mitogenome were detected. …”
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