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HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors
Published 2025-07-01“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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1522
Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma.
Published 2014-01-01“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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1523
Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection.
Published 2016-01-01“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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1524
Bird response to intercropping switchgrass within a loblolly pine plantation
Published 2017-12-01“…ABSTRACT Global interest in alternative, renewable energy sources has led to the development of novel land‐use practices and techniques aimed at maximizing energy production while also minimizing environmental, economic, and societal costs. …”
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1525
The engineering toolbox of Parageobacillus thermoglucosidasius
Published 2025-07-01“…The focus of this review is to provide an organised summary of the currently available resources to facilitate the use of this organism. The article offers a comprehensive overview of regulatory parts used for the construction of genetic circuits and plasmids, including promoters, ribosome binding sites, terminators, antibiotic resistance genes, reporter genes, and other genetic elements of interest. …”
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Sunlight Noise Mitigation in FMCW LiDAR Using FADOF
Published 2024-01-01“…Additionally, the system achieves a detection range of at least 17 meters under direct sunlight conditions. …”
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1528
Comparison of Two System Identification Approaches for a Four-Wheel Differential Robot Based on Velocity Command Execution
Published 2025-06-01“…These results demonstrate the relationship between model complexity and accuracy and suggest that the motor-specific model is more appropriate for applications requiring precise mapping or localization, such as SLAM, while the simplified model may be suitable for simpler use cases with lower computational requirements, such as embedded systems with limited resources. This paper provides a practical evaluation of the accuracy and computational performance of two modeling approaches, highlighting the implications of model selection for the design of navigation tasks.…”
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1529
Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review
Published 2025-05-01“…The main literature searches were then conducted using six databases: Applied Social Sciences Index and Abstracts (ProQuest), Cumulative Index to Nursing and Allied Health Literature (EBSCO), MEDLINE (Ovid), PsycInfo (Ovid), EMBASE (Ovid) and Web of Science Core Collection (Emerging Sources Citation Index). The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. …”
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1530
PATH PLANNING AND OBSTACLE AVOIDANCE METHODS FOR AUTONOMOUS MOBILE ROBOTS
Published 2024-12-01“…The modification of the classical artificial potential field method using the Gaussian function to describe repulsive forces is an example of optimizing the method for systems with constrained resources. …”
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1531
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Neural Correlates of Changes in a Visual Search Task due to Cognitive Training in Seniors
Published 2012-01-01“…This study aimed to elucidate the underlying neural sources of near transfer after a multidomain cognitive training in older participants in a visual search task. …”
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1534
Crop pangenomes
Published 2021-03-01“…The published genomes of agricultural plants proved to be a valuable tool for studing gene functions and for marker-assisted and genomic selection. …”
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1535
Conceptual Development of Urban Super-blocks Model in Urban Planning Based on Content Analysis Method
Published 2024-09-01“…Based on the analysis and synthesis of the findings, 101 open codes have been identified regarding the unique characteristics of urban superblocks, which have been classified into 31 core codes. Axial codes in six selected codes are classified including background conditions (superblock and mini-block environment), causal conditions (field of urban action, land use and urban morphology, urban function, urban complexity, biodiversity and urban green, metabolic efficiency , social unity, human-centered street, complete streets, healthy streets and sustainable streets), mediating conditions (good urban governance and mixed use), central category (biological and physiological needs, security needs, belonging needs, respect needs, cognitive needs, aesthetic needs and self-fulfillment needs), strategies (green space redesign, space reassignment and restrictions and active transportation) and consequences (environmental improvement, traffic reduction, air pollution reduction, social cohesion, health promotion, economic). …”
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1536
A new fluorescent probe based on BODIPY for testing NO2 released from propellants
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1537
Optimal band selection and transfer in drone-based hyperspectral images for plant-level vegetable crops identification using statistical-swarm intelligence (SSI) hybrid algorithms
Published 2025-05-01“…Hyperspectral imagery from drones are excellent sources of high-resolution plant-level data that helps in efficient crop identification for smart agriculture practices. …”
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1538
Simultaneous removal and optical determination of mercury ions by constructing fluorescent recombinant T. thermophila SB210 strains
Published 2025-06-01“…Removing and monitoring Hg2+ ions in the pollution sources based on microorganisms have the advantages of low cost and convenience. …”
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1539
Validation of the inadequate delivery of oxygen index in an adult cardiovascular intensive care unitCentral MessagePerspective
Published 2024-12-01“…Conclusions: The IDO2 index is capable of detecting SvO2 ≤50% with good discriminatory function in non-MCS CVICU patients in a variety of monitoring situations. …”
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1540
ACO-NM hybrid optimization calculation method for transit time of oxygen activation logging in CO2 injection profile
Published 2025-08-01“…Compared with the measured oxygen activation spectrum peak, the Gaussian function exhibited a high degree of morphological similarity. …”
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