State immunological reactivity and autonomic regulation in patients with chronic apical periodontitis

“…In this paper we studied 107 people with a diagnosis of «chronic apical periodontitis». The functional state of the autonomic nervous system were detected by electrophoresis dosed adrenaline and carbachol and test dermographism. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Key outcomes that determine overall resource use are medical management (treatments and consultation time) and referral rates. …”
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Landscape of extracellular small RNA and identification of biomarkers in multiple human cancers by Shoubin Zhan, Ye Xu, Botao Li, Peng Ge, Chunwu Zhang, Shengkai Zhou, Tingting Yang, Gaoli Liang, Ling Ji, Xiangbin Kong, Ping Yang, Xi Chen, Chen-Yu Zhang, Han Shen, Xu Luo, Zhen Zhou, Yanbo Wang

“…Summary: Extracellular RNAs (exRNAs) in biofluids, sourced from diverse tissues, exhibit various biological functions and diagnostic potential. …”
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Genomics and integrative clinical data machine learning scoring model to ascertain likely Lynch syndrome patients by Ramadhani Chambuso, Takudzwa Nyasha Musarurwa, Alessandro Pietro Aldera, Armin Deffur, Hayli Geffen, Douglas Perkins, Raj Ramesar

“…Annovar, Intervar, Variant Effect Predictor (VEP), and OncoKB software tools were used to functionally annotate and interpret somatic variants detected. …”
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The Effect of Heat Stress on the Performance and Genetic Parameters of Milk Production, Reproduction, and Somatic Cell Scores in Iranian Holstein Cows by Reza Seyedsharifi, Fatemeh Ala Noshahr, Jamal Seif Davati, Nemat Hedayat Evrigh

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Reconstruction of defects in elastic bodies by combination of genetic algorithm and finite element method by Arkady N Solovyev, Mikhail Y. Shevtsov

“…The inverse problem solution is based on the minimization of the residual functional between the measured input source information and the data calculated during the numerical solution of direct problems with the given parameters of defects. …”
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Synthesis and Production of Sweet-Tasting Protein in E. coli and Purification by Amylose Resin by F. Mansouri

“…However, the extraction of brazzein from its natural source is expensive and not applicable. In this study we used recombinant DNA technology to provide an alternative option for cheaper mass production of brazzein. …”
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Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis by Zilin Hua, Nan Zhou, Zijing Zhou, Zewei Fu, Ruiyun Guo, Herman Yao Akogo, Jiayin Yang, Meixuan Yu, Yujie Jiang, Siyi Lan, Haixia Chang, Jun Ma, Huixian Cui

“…Subgroup analyses indicated that stem cell source, stem cell derivative types and Aβ detection method were not primary drivers of heterogeneity. …”
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Phenolic Content, Antioxidant Activity and Quality Characteristics of Hulled Wheats Originating from Türkiye by Fatma Ruveyda Alkan, Buket Çetiner, Hüseyin Akşit, Samed Şimşek

“…These findings demonstrate notable diversity among hulled wheats regarding the evaluated traits and suggest their potential as valuable genetic resources for wheat breeding programs.…”
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Proteomic analysis of Buffalo milk somatic cells reveals metabolomic and immunological transitions during early lactation by Priyanka M. Kittur, Lija Satheesan, Narasimha Tanuj Gunturu, Yallappa M. Somagond, A. P. Madhusoodan, Ravi Kumar Gandham, Rani Alex, Ajay Kumar Dang

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Lipidomic Profiling of Edible Japanese Sea Urchins by LC–MS by Sahana Amai, Kisara Yuki, Siddabasave Gowda B. Gowda, Divyavani Gowda, Shu-Ping Hui

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Monitoring a New England Cottontail Reintroduction with Noninvasive Genetic Sampling by Melissa L. Bauer, Brett Ferry, Heidi Holman, Adrienne I. Kovach

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Inference of a plume conduit beneath the Réunion Island from 3D migration of Ps conversions from the mantle transition zone by B. Padma Rao, M. Ravi Kumar

“…These maiden results shed-light on the high-temperature anomalies in the mid-mantle, probably sourced from the Réunion plume and provide evidence for the Majorite-garnet phase transformation at 660 km discontinuity. …”
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High host specificity of alphacoronaviruses in Nearctic, insectivorous bats by Jonathon D. Kotwa, Arkadeb Bhuinya, Winfield Yim, Giulia Gallo, Pahul Singh, Qiang Liu, Anil Kumar, Emily Chien, Aaron Hou, Hsien-Yao Chee, Juliette Blais-Savoie, Lily Yip, Valerie Von Zuben, K. Aidan Wouters, Vikram Misra, Oliver Lung, Dalan Bailey, Finlay Maguire, Arinjay Banerjee, Samira Mubareka, Christina M. Davy

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Identification of WRKY gene family and analysis of drought stress expression in Poncirus polyandra by ZHANG Shanshan, RUAN Sunmei, YANG Wenzhong

“…This study provides new information for analysing the function of WRKY gene and its regulatory mechanism in response to drought stress in P. polyandra, and supplies excellent genetic resources for breeding drought-tolerant citrus varieties.…”
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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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Environmental Levels and Degradation Behavior of Pharmaceuticals and Personal Care Products (PPCPs) in the Water Environment by Zhaohe ZHANG, Dian CHEN, Wei ZHAO, Guoli YUAN, Jun LI, Xingchun JIAO

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PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm by Naeem Shirmohammady, Habib Izadkhah, Ayaz Isazadeh

“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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