Clinical profile and molecular genetic analysis of alport syndrome in children: a single center experience by Aqsa Ahmad, Aqsa Ahmad, Liang Lijun, Zhang Yan, Zhang Yan, Ma Yan, Zhao Shuai, Zhao Shuai, Du Wangnan, Du Wangnan

“…Genetic testing emerged as a critical resource for diagnosing AS. Furthermore, early diagnosis is crucial for implementing an appropriate management plan and assessing the prognosis.…”
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SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels by Gang He, Mei Liu, Tang cong Chen, Li fen Huang, You qiang Ke

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Glucosylceramides containing very long-acyl-chain fatty acid are critical for cotton fiber elongation by influencing brassinosteroid synthesis and signaling by Qiaoling Wang, Xingying Yan, Qi Niu, Hongju Zhang, Huidan Tian, Zheng Chen, Fan Xu, Yu You, Yinghui Gao, Zhiqing Qiao, Ming Luo

“…Cotton fiber is one of the longest plant cells and sphingolipids are closely associated with the development of cotton fiber cells. However, their function in cotton fiber cell development and its action mechanism is unclear. …”
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Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice by Tetsushi Kagawa, Yuhei Yamaguchi, Yasuhiro Kokubu, Genki Sudo, Aoi Ebisawa, Satoko Hattori, Keizo Takao, Kohtarou Konno, Naomi Nakagata, Takafumi Inoue, Masahiko Watanabe, Johji Inazawa, Tsuyoshi Miyakawa, Tetsuya Taga

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Characteristics of chemically induced liver progenitors derived from a pig model of metabolic dysfunction-associated steatotic liver disease. by Masayuki Fukumoto, Daisuke Miyamoto, Akihiko Soyama, Takanobu Hara, Yasuhiro Maruya, Peilin Li, Hajime Matsushima, Kazushige Migita, Takahiro Enjoji, Hanako Tetsuo, Takuro Fujita, Mampei Yamashita, Hajime Imamura, Tomohiko Adachi, Kengo Kanetaka, Takahiro Ochiya, Susumu Eguchi

“…In contrast, markers of functional MH after re-differentiation were only detected in the healthy group. …”
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Assembly and comparative analysis of the complete mitochondrial of Spodiopogon sagittifolius, an endemic and protective species from Yunnan, China by Chao Xu, Wei Bi, Ren-yi Ma, Pin-rong Li, Feng Liu, Zhen-wen Liu

“…Abstract Background Spodiopogon sagittifolius, a C4 plant closely related to cultivated crops, is an edible resource and a Class II nationally protected species in China. …”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

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Stage-specific metabolic allocation: nutrient investment strategies during Lysiphlebia japonica Ashmead development by Tingting Zhou, Ningbo Huangfu, Li Wang, Junyu Luo, Jinjie Cui, Xiangzhen Zhu, Sumei Wan, Xueke Gao

“…Nutrients, particularly lipids and energy-related metabolites, play a critical role in shaping stage-specific growth and survival strategies in parasitic wasps.MethodsTo analyze the allocation patterns of metabolite resources during development of parasitoid wasps, the multi-omics analysis was employed to systematically investigate nutrient dynamics across three growth periods in Lysiphlebia japonica Ashmead, a major parasitoid of cotton aphid (Aphis gossypii Glover).ResultsHere, a total of 753 metabolites were detected by untargeted metabolomics, with numerous nutritionally critical compounds including amino acids, fatty acids and carbohydrates showed stage-specific variations. …”
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INTERACTION BETWEEN DENTO-MAXILLOFACIAL ANOMALIES AND GENERAL-SOMATIC HUMAN CONDITION (LITERATURE REVIEW) by L.V. Smaglyuk, H.V. Voronkova, A.Ye. Karasiunok, A.V. Liakhovska, V.I. Smaglyuk

“…Materials and methods. Literary sources were reviewed on the relationship of malocclusion with the general diseases and the obtained data were analysed. …”
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Optimizing maize germination forecasts with random forest and data fusion techniques by Lili Wu, Yuqing Xing, Kaiwen Yang, Wenqiang Li, Guangyue Ren, Debang Zhang, Huiping Fan

“…This study selected the Zheng Dan-958 maize variety to predict germination rates using multi-source information fusion and a random forest (RF) algorithm. …”
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Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep by XinKun Wang, Wei Li, QiaoYan Huang, HuiPing Sun, LeXiao Zhu, RuoHuai Gu, Feng Xing

“…We identified 290 selected regions and 332 genes across the Hotan sheep genome by using two widely adopted selective scanning detection methods (FST statistics and Piratio). Functional annotation and enrichment analysis of these genes identified 13 genes associated with the lambing rate, which were enriched in pathways such as the transforming growth factor-β signaling pathway (BMPR2, ID2, SMAD7, THBS1, and RBX1), renal cell carcinoma (PAK1, ELOC), inositol phosphate metabolism (PLCZ), non-homologous terminal junction (RAD50), ABC transporters (ABCC4), and the NET pathway (H2B, H4, and H2A). …”
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Genome-wide association study identifies candidate SNP markers and genes associated with low nitrogen tolerance in Brassica napus by Jingdong Chen, Jingdong Chen, Lingli Xie, Xianfei Hou, Rui Yang, Jin Liu, Xigang Dai, Tianyuan Xue, Shuai Yin, Benbo Xu, Xuekun Zhang, Changli Zeng, Jinsong Xu

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Spatial Appraisal of Seasonal Water Yield of the Sokoto-Rima Basin by Shakirudeen Odunuga, Mayowa Fasona, Saheed Adekunle Raji

“…Understanding the dynamics of water yield as relates to water balance is vital for the functioning of ecosystems as well as model-based computation of their respective ecosystem services. …”
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Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours by Tobias Åkerström, Branislav Klimàcek, Matilda Annebäck, Olov Norlén, Peter Stålberg

“…Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. …”
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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…The innovation of the SEAttention module lies in replacing the original activation function with the Mish activation function, which can dynamically adjust the weights of different channels to enhance performance. …”
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Short-Term Fertilization with the Nitrogen-Fixing Bacterium (NFB) <i>Kosakonia radicincitans</i> GXGL-4A Agent Can Modify the Transcriptome Expression Profiling of Cucumber (<i>Cuc... by Baoyun Feng, Erxing Wang, Yating Zhang, Lurong Xu, Yanwen Xue, Yunpeng Chen

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Diverse ancestral representation improves genetic intolerance metrics by Alexander L. Han, Chloe F. Sands, Dorota Matelska, Jessica C. Butts, Vida Ravanmehr, Fengyuan Hu, Esmeralda Villavicencio Gonzalez, Nicholas Katsanis, Carlos D. Bustamante, Quanli Wang, Slavé Petrovski, Dimitrios Vitsios, Ryan S. Dhindsa

“…These findings highlight the need for enhanced population representation in genomic resources to fully realize the potential of precision medicine and drug discovery. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Mid-infrared Ensemble Variability of Broad-line and Narrow-line Seyfert 1 Galaxies by Zhipeng Hu, Lisheng Mao

“…The MIR variability of the combined sample is positively correlated with black hole mass and the FWHM of the H β emission line at long rest-frame time lags. (4) The long-term MIR variability of the combined sample may be mainly driven by the Eddington ratio. (5) For BLSy1 galaxies, the MIR variability of radio-detected sources is greater than that of radio-undetected sources, whereas for NLSy1 galaxies, the opposite is true.…”
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From the WHO framework to integrated senior health and wellness hub program: an implementation journey by Xiaoting Huang, Xiaoting Huang, Hao Yi Tan, Hao Yi Tan, Hao Yi Tan, Pei Ling Er, Amber Wong, Si Qi Lim, Joshua Kuan Tan, Wan Qi Yee, Xiaohui Xin, Lian Leng Low

“…IntroductionAs global populations age, ensuring older adults maintain functional ability and wellbeing is a critical public health priority. …”
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