LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION by V. Sarancha, K. Vitale, S. Oreskovic, V. Sulyma

“…Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.…”
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Oligosaccharide production using β-galactosidase from Lactobacillus bulgaricus and Kluyveromyces lactis in sweetened reconstituted nonfat dry milk by Giselle K.P. Guron, Arland T. Hotchkiss, Jr., Brittany H. Bodnar, Andrew Harron, John A. Renye, Jr., Michael J. McAnulty

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Genetic Factors for the Natural Elimination of Hepatitis C Virus by N. V. Vlasenko, T. A. Loscutova, K. O. Mironov, A. S. Esman, E. A. Dunaeva, T. A. Semenenko, D. B. Dubodelov, M. I. Korabelnikova, Z. B. Ponezheva, V. V. Makashova, K. G. Omarova, A. V. Sacuk, G. G. Solopova, S. N. Kuzin, V. G. Akimkin

“…Additionally, the significance of polymorphisms at the intragenic and intergenic levels was assessed using modern bioinformatic resources in the field of functional genomics.Results. …”
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Survey on Backdoor Attacks on Deep Learning: Current Trends, Categorization, Applications, Research Challenges, and Future Prospects by Muhammad Abdullah Hanif, Nandish Chattopadhyay, Bassem Ouni, Muhammad Shafique

“…On the one hand, the availability of MLaaS (or third-party resources) alleviates this issue. On the other hand, it opens up avenues for a new set of vulnerabilities, where an adversary (someone from a third party) can infect the model with malicious functionality that is triggered only with specific input patterns. …”
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Exploration of the interaction between antimicrobial peptides and gamma radiation for biosensor development. by Fabiane Modenese Garbim, Marcela Rabelo De Lima, Giulianna Santos Pereira, João Nilton Conceição Bandeira, Álvaro José Mendes-Boareto, Fernando Manuel Araújo-Moreira, N.F.G. Serrano

“…The total extract (TE) containing the AMPs was irradiated in a Gamacell 220 irradiator with a Co-60 source at the Radiation Technology Center (CTR) of IPEN, subjected to doses of 0.5, 1.0, 4.0, and 10.0 Gy under controlled conditions. …”
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Dietary Jerusalem artichoke polysaccharide supplementation alters the growth performance, ruminal microbes and metabolites, muscle fatty acid and amino acid profiles in fattening l... by Cuihua Guo, Dongmei Ma, Chongyu Zhang, Yunpeng Wang, Farman Ullah, Xiaojun Wang, Yunkyoung Lee, Guiguo Zhang

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circPTN Promotes the Progression of Non-Small Cell Lung Cancer through Upregulation of E2F2 by Sponging miR-432-5p by Jiayuan Su, Jinrong Zhou, Yachan Feng, Haojie Zhang, Xinyu Zhang, Xiaorong Zhao, Yong Li, Xueling Guo

“…The molecular targets of cicrPTN were predicted using starBase online resources, which was validated by RNA immunoprecipitation (RIP) and dual-luciferase reporter assay. …”
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Genome-wide identification and expression pattern analysis of NAC family in Taxus yunnanensis and the TyuNAC30 role in paclitaxel production by Jiangtao Fan, Yong Wang, Mengke Dou, Qiuhong Hu, Qing Li, Shengmei Gan, Mingwei Jing, Gang Wang, Xiong Huang

“…Taxus yunnanensis, a well-known medicinal plant, is the natural source of the anticancer diterpene paclitaxel. Despite the biological importance of NAC transcription factors, no comprehensive genome-wide study of the NAC gene family has been conducted in T. yunnanensis. …”
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Prediction of Genes Related to Positive Selection Using Whole-Genome Resequencing in Three Commercial Pig Breeds by HyoYoung Kim, Kelsey Caetano-Anolles, Minseok Seo, Young-jun Kwon, Seoae Cho, Kangseok Seo, Heebal Kim

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Evaluation of meningitis surveillance system in rural area, Rwanda by Solange Nyinawabeza, Jean Claude Niyoyita, Emmanuel Nshimiyimana, Jerome Ndayisenga, Angela Umutoni, Caroline Stamatakis

“…Data collected from clinical registers and eIDSR were used to assess core functions of the meningitis surveillance system including accuracy in detection of cases, laboratory confirmation of cases, and availability of evaluation reports. …”
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Genome-Wide Association Study of Immune Indices in Yaks by Daoning Yu, Xiaoming Ma, Chun Huang, Tong Wang, Mengfan Zhang, Fen Feng, Xiaoyun Wu, Yongfu La, Xian Guo, Ping Yan, Derong Zhang, Chunnian Liang

“…The yak is a vital livestock resource on the Qinghai–Tibet Plateau, renowned for its strong disease resistance and high-quality meat. …”
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Identifying Disinformation on the Extended Impacts of COVID-19: Methodological Investigation Using a Fuzzy Ranking Ensemble of Natural Language Processing Models by Jian-An Chen, Wu-Chun Chung, Che-Lun Hung, Chun-Ying Wu

“…MethodsA comprehensive dataset comprising 566 genuine and 2361 fake samples was curated from reliable open sources and processed using advanced techniques. The dataset was randomly split using the scikit-learn package to facilitate both training and evaluation. …”
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A New [PMo₁₂O₄₀]³⁻-Based Ni^II Compound: Electrochemical and Photocatalytic Properties for Water Pollutant Removal by Guoqing Lin, Shufeng Liu, Dai Shi, Ying Yang, Fangle Yu, Tong Lu, Xiao-Yang Yu, Yuguang Zhao

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Fatty acid composition and antioxidant capacity of defatted, non-defatted and oils extracts of Quercus ilex fruit from Algeria by Hadjira Guenane, Boulanouar Bakchiche, Ramazan Erenler, Ilyas Yildiz, Omar M. Khalaf, Amal M. Saad, Mosad A. Ghareeb

“…Background The nutritional value and health-promoting properties cause the fruits (acorns) of Quercus ilex to have great potential for use in the food industry as functional ingredients and antioxidants source. Objective In this study, the amount of total phenolic compounds, flavonoids in different extracts (defatted, non-defatted) and composition of fatty acids in the fruits oils of Quercus ilex were investigated. …”
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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

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Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis by Dayan Hu, Jieliang Jian, Jinpeng Zhang, Xiaojun Xu, Shu Wang, Cuiping Gong, Yuanqin Zhang, Pengcan Zhu, Zhimin Gu, Wenzhi Guan

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Optimizing extraction of microbial DNA from urine: Advancing urinary microbiome research in bladder cancer by Chuang-Ming Zheng, Ho Won Kang, Seongmin Moon, Young Joon Byun, Won Tae Kim, Yung Hyun Choi, Sung-Kwon Moon, Xuan-Mei Piao, Seok Joong Yun

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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin by Liping Wang, Shufang Wang, Jing Li, Xingnan Zhang

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Overexpression of ST8Sia1 inhibits tumor progression by TGF-β1 signaling in rectal adenocarcinoma and promotes the tumoricidal effects of CD8+ T cells by granzyme B and perforin by Chang Zhang, Yeli Wang, Yao Yu, Yanchao Pang, Xiao Xiao, Leilei Hao

“…Background Rectal adenocarcinoma (READ) involves the dysregulated expression of alpha 2,8-Sialyltransferase1 (ST8Sia1) although its role during READ’s progression is unclear.Methods The mRNA level of ST8Sia1 was analyzed based on The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Tumor Immune Estimation Resource (TIMER) 2.0. Furthermore, the prognostic and significance of ST8Sia1 in READ was assessed through Kaplan-Meier curve, univariate, multivariate Cox regression, and receiver operating characteristic (ROC) methods. …”
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Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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