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Application of CRISPR-Cas System in Human Papillomavirus Detection Using Biosensor Devices and Point-of-Care Technologies
Published 2025-01-01“…Therefore, the development of rapid, high-throughput, and sensitive HPV detection platforms is important, especially in regions with limited access to advanced medical resources. …”
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503
YOLO-LSM: A Lightweight UAV Target Detection Algorithm Based on Shallow and Multiscale Information Learning
Published 2025-05-01“…To address challenges such as large-scale variations, high density of small targets, and the large number of parameters in deep learning-based target detection models, which limit their deployment on UAV platforms with fixed performance and limited computational resources, a lightweight UAV target detection algorithm, YOLO-LSM, is proposed. …”
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Proteolysis and volatile compounds in Mediterranean buffalo milk blue cheese: Quality determinants and functional peptides
Published 2025-06-01“…This study explores the proteolytic changes and volatile organic compound (VOC) profiles occurring during the ripening of Mediterranean buffalo milk blue cheese.The main objective was to characterize bioactive peptides, casein phosphopeptides, and volatile compounds and to assess their potential implications for functional food development.Peptide profiling was conducted using nanoLC-ESI-MS/MS and MALDI-TOF-MS, while VOCs were analyzed via headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME)-GC-MS.β-casein emerged as the predominant source of bioactive peptides, including sequences with predicted ACE-inhibitory, antimicrobial, and antioxidant activities. …”
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Fermented Buffalo Milk with Conjugated Linoleic Acid-Producing Bacteria: Strain Selection and Functional Applications
Published 2025-05-01“…Buffalo milk is a rich source of precursor fatty acids for bioactive compounds and provides an optimal environment for bacterial growth. …”
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The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis
Published 2025-04-01“…BackgroundWhile numerous previous studies have indicated that nicotine intake results in gray matter and functional brain abnormalities in tobacco use disorder (TUD), the majority of results could not be replicated or even reversed. …”
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SDKU-Net: A Novel Architecture with Dynamic Kernels and Optimizer Switching for Enhanced Shadow Detection in Remote Sensing
Published 2025-02-01“…To address these issues, this study proposes the Supervised Dynamic Kernel U-Net (SDKU-Net), a novel architecture designed to enhance shadow detection in complex remote sensing scenarios. SDKU-Net integrates dynamic kernel adjustment, a combined loss function incorporating Focal and Tversky Loss, and optimizer switching to effectively tackle class imbalance and improve segmentation quality. …”
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Comparative study on bivariate statistical characteristics of drought in Shandong using SPI and SPEI
Published 2025-04-01“…A comparison of the return period using the bivariate copula function indicated that minor differences existed for the same drought event in the same meteorological station of SPI and SPEI. …”
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Aqueous extracts of Portulaca oleracea L. alleviate atopic dermatitis by restoring skin barrier function
Published 2025-06-01Get full text
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Three‐Dimensional Habitat Structure Drives Avian Functional and Trait Diversity Across North America
Published 2025-04-01Get full text
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Functional kombucha production from fusions of black tea and Indian gooseberry (Phyllanthus emblica L.)
Published 2024-12-01Get full text
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Deep Defense Against Mal-Doc: Utilizing Transformer and SeqGAN for Detecting and Classifying Document Type Malware
Published 2025-03-01“…The proposed model will solve this gap by detecting and classifying document-type malware families using script codes, including tags, to write documents and script languages to execute malicious functions. …”
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DMM-YOLO: A high efficiency soil fauna detection model based on an adaptive dynamic shuffle mechanism
Published 2025-08-01“…Abstract Soil fauna play a critical role in maintaining ecosystem functions and assessing environmental health, making accurate and efficient detection essential. …”
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Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases
Published 2025-06-01“…Herein, we report a simple method of functionalization of poly(methyl methacrylate) (PMMA) with polylysine to be used as the microfluidic microplate substrate for enhanced ELISA, enabling rapid, ultrasensitive, and multiplexed detection of infectious diseases. …”
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Plasmonic optical fiber biosensors for ultra-low detection of respiratory syncytial virus via point-of-care tests
Published 2025-06-01“…Hence, the results establish the POF-based RSV biosensor as a sensitive, cost-effective, ultra-fast, capable of being connected to the Internet, and a scalable alternative to traditional RSV detection methods, offering a promising tool for improving diagnostic capabilities in clinical and resource-limited settings.…”
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Waterbody Detection and Reservoir Water Level Prediction Using Bayesian Mixture Models with Sentinel-1 GRD Data
Published 2025-03-01“…For future research, higher-resolution data or complementary algorithms may further enhance detection accuracy for smaller and more complex water features, contributing to more refined water resource management strategies.…”
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Edge enhancement of potential field data using the enhanced gradient (EG) filter
Published 2024-08-01“…The EG is tested on two dimensional (2D) and three dimensional (3D) synthetic magnetic models with sources buried at different depths and variable properties. …”
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Innovative machine learning-based prediction of early airway hyperresponsiveness using baseline pulmonary function parameters
Published 2025-08-01“…BackgroundThe Bronchial Provocation Test (BPT) is the gold standard for diagnosing airway hyperresponsiveness (AHR) in suspected asthma patients but is time-consuming and resource-intensive. This study explores the potential of baseline pulmonary function parameters, particularly small airway indices, in predicting AHR and develops a machine learning-based model to improve screening efficiency and reduce unnecessary BPT referrals.MethodsThis retrospective study analyzed baseline pulmonary function data and BPT results from Henan Provincial People’s Hospital (May to September 2024). …”
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