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20401
Strategic optimization of engine performance and emissions with bio-hydrogenated diesel and biodiesel: A RVEA-GRNNs framework
Published 2024-12-01“…The Generalized Regression Neural Networks model demonstrated high accuracy in predicting engine performance and emissions, with coefficient of determination (R2) values exceeding 0.98 and mean absolute percentage errors below 5 %. …”
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20402
Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity
Published 2025-01-01“…Here we use SolubiS and dTANGO, computational algorithm-based methods, to predict mutations within the IL2 structure to improve protein production yield in muteins with altered cellular selectivity, to generate combined muteins with elevated therapeutic potential. …”
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20403
Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression
Published 2025-06-01“…Particularly, IL32high Treg imparted an essential effect on tumor evasion and predicted a worsened prognosis of TNBC patients. Furthermore, MCI model enabled to notify the inferior prognosis and immunotherapy resistance in TNBC. …”
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20404
A cloud-metaheuristic-based framework for stochastic optimization of a hybrid wind/hydrogen based-Fuel cell system in distribution network considering uncertainty
Published 2025-08-01“…An improved Fire Hawks Optimization (IFHO) algorithm is utilized in solving the optimization problem by determining the optimal installation locations and sizes of HRES components. …”
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20405
Preliminary evaluation of ShallowHRD performance compared to HRDetect in familial breast cancer tumors
Published 2025-08-01“…Abstract Determining the Homologous Recombination Deficiency (HRD)-status of a malignant tumor is central in predicting patient response to specific treatments. …”
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20406
Serum Lipid Biomarkers for the Diagnosis and Monitoring of Neuromyelitis Optica Spectrum Disorder: Towards Improved Clinical Management
Published 2025-03-01“…Additionally, a combination of these lipid biomarkers was found to predict relapse with the AUC of 0.861. A user-friendly smartphone application was developed to facilitate the straightforward “input-index, output-answer” screening process, enhancing both clinical decision-making and patient care.Conclusion: The diagnostic model based on the serum lipid-related indexes (TC, TG, LDL, HDL, ApoA1, and ApoB) may be the useful tool for NMOSD in diagnosis and monitoring of disease stage, thereby improving the treatment outcome for patients. …”
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20407
Experimental Study on Compressive Capacity Behavior of Helical Anchors in Aeolian Sand and Optimization of Design Methods
Published 2025-07-01“…The compressive capacity of helical anchors constitutes a pivotal performance parameter in geotechnical design. To precisely predict the compressive bearing behavior of helical anchors in aeolian sand, this study integrates in situ testing with finite element numerical analysis to systematically elucidate the non-linear evolution of its load-bearing mechanisms. …”
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20408
Immunotyping of thyroid cancer for clinical outcomes and implications
Published 2025-05-01“…Furthermore, the prognostic model’s utility in predicting immunotherapy response was analyzed. The potential therapeutic drugs were obtained. …”
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20409
Simplification of the diagnostic approach and treatment of Hepatitis C Virus.
Published 2025-04-01“…Fibrosis was calculated using the APRI algorithm, finding 53/130 with >1.5 and 60/130 with >3.25, which predicted F3-4. …”
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20410
Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medici...
Published 2025-07-01“…The model quality was evaluated by 7-fold cross-validation, and the model validity was evaluated based on R²Y (interpretability of categorical variable Y) and Q² (predictability of the model), and the permutation test was used for further verification. …”
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20411
Novel computational One-Health analysis of fibrinogen-binding protein A in Streptococcus agalactiae Isolated from fish and human cases
Published 2025-05-01“…Three-dimensional structures were predicted through ColabFold and validated using Ramachandran plots. …”
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20412
Klasifikasi Kinerja Akademik Siswa Menggunakan Neighbor Weighted K-Nearest Neighbor dengan Seleksi Fitur Information Gain
Published 2022-06-01“…Neighbor Weighted K-Nearest Neighbor algorithm with Information Gain method will be applied to this study to help predict student performance. …”
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20413
Development of policy research-evidence organizer and public health-policy evaluation tool (prophet): a computing paradigm for promoting evidence-informed policymaking in Nigeria
Published 2024-12-01“…It strategically evaluates and assess level of evidence content, and predict implementation prospects of health policy documents.…”
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20414
Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: a cross-sectional study
Published 2025-07-01“…Loneliness was assessed using the Three-Item Loneliness Scale. Factors predicting mental health problems with a K6 score ≥ 5 were explored using the Mann–Whitney U test, Fisher’s exact probability test, and classification and regression tree (CART) analysis. …”
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20415
Identification and Validation of Key Genes Related to Lipophagy in Osteoporosis
Published 2025-07-01“…In addition, we constructed a nomogram to predict the incidence of OP patients. Subsequently, multiple bioinformatics tools were used to reveal the associations between key genes and OP. …”
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20416
Comparative estimation of the effectiveness of the Khorana, Vienna CATS, and TiC-Onco scores and the vWF/ADAMTS13 ratio in identifying a high risk of thrombotic complications in pa...
Published 2025-05-01“…The Khorana, Vienna CATS, and TiC-Onco scores demonstrate moderate accuracy in predicting thrombosis in cancer patients, partly due to their inability to consider the individual characteristics of endothelial dysfunction and/or overestimation of the impact of “silent” genetic mutations. …”
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20417
Post-hoc Evaluation of Sample Size in a Regional Digital Soil Mapping Project
Published 2025-03-01“…Furthermore, the comparison of the optimal maps to the reference maps showed little difference in the global statistics (concordance correlation coefficient and root mean square error) and spatial trends of the data, confirming that the optimal sample size was sufficient for creating predictions of similar accuracy to the full calibration dataset. …”
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20418
Reinforcement learning-based vehicle travel path reconstruction from sparse automatic licence plate recognition data
Published 2025-04-01“…Finally, the Q-learning algorithm is utilized to reconstruct vehicle travel paths between adjacent ALPR sensors based on the comprehensive reward function. …”
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20419
An Update on Hepatorenal Syndrome
Published 2017-03-01“…HRS is associated with poor prognosis and represents the end-stage of a sequence of reductions in renal perfusion induced by progressively severe hepatic injury. …”
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20420
Development of an accessible system to enhance driving instruction for individuals with hearing impairments
Published 2025-04-01“…The project’s approach introduces innovative methodologies compared to those used in other countries, contributing to educational and inclusive advancement through technology. …”
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