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Identifying Molecular Properties of Ataxin-2 Inhibitors for Spinocerebellar Ataxia Type 2 Utilizing High-Throughput Screening and Machine Learning
Published 2025-05-01“…The molecular descriptor data (MD model) was analyzed separately from the experimentally determined screening data (S model) as well as together (MD-S model). …”
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243
Optimizing protein-ligand docking through machine learning: algorithm selection with AutoDock Vina
Published 2025-07-01“…Abstract Context Understanding protein-ligand interactions is fundamental to drug design, where optimizing docking parameter selection can potentially enhance computational efficiency and resource allocation in virtual screening. While numerous algorithms exist for protein-ligand docking, achieving an optimal balance between accuracy and computational speed remains challenging. …”
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244
Digital innovation in healthcare: quantifying the impact of digital sepsis screening tools on patient outcomes—a multi-site natural experiment
Published 2025-04-01“…We evaluated the impact of sepsis screening tools on in-patient 30-day mortality across four multi-hospital NHS Trusts, each using a different algorithm for early detection of sepsis.Methods Using quasi-experimental methods, we investigated the impact of the screening tools. …”
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245
An Automated Algorithm for Obstructive Sleep Apnea Detection Using a Wireless Abdomen-Worn Sensor
Published 2025-04-01“…Wireless wearable devices have emerged as promising tools for OSA screening and follow-up. This study introduces a novel automated algorithm for detecting OSA using abdominal movement signals and acceleration data collected by a wireless abdomen-worn sensor (Soomirang). …”
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Deep learning-assisted screening and diagnosis of scoliosis: segmentation of bare-back images via an attention-enhanced convolutional neural network
Published 2025-02-01“…We have developed a deep learning-based image segmentation model to enhance the efficiency of scoliosis screening. …”
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247
A novel myocarditis detection combining deep reinforcement learning and an improved differential evolution algorithm
Published 2024-12-01“…To overcome these challenges, the approach proposed incorporates advanced techniques such as convolutional neural networks (CNNs), an improved differential evolution (DE) algorithm for pre‐training, and a reinforcement learning (RL)‐based model for training. …”
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248
In Silico Evaluation of Algorithm-Based Clinical Decision Support Systems: Protocol for a Scoping Review
Published 2025-01-01“…MethodsWe propose a scoping review protocol that follows an enhanced Arksey and O’Malley framework and PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines to investigate the scope and research gaps in the in silico evaluation of algorithm-based CDS models—specifically CDS decision-making end points and objectives, evaluation metrics used, and simulation paradigms used to assess potential impacts. …”
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Surrogate-assisted global and distributed local collaborative optimization algorithm for expensive constrained optimization problems
Published 2025-01-01“…For global surrogate-assisted collaborative evolution phase, the global candidate set is generated through classification collaborative mutation operations to alleviate the pre-screening pressure of the surrogate model. For local surrogate-assisted phase, a distributed central region local exploration is designed to achieve intensively search for promising distributed local areas which are located by affinity propagation clustering and mathematical modeling. …”
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250
One scan, multiple insights: A review of AI-Driven biomarker imaging and composite measure detection in lung cancer screening
Published 2025-03-01“…Through an extensive review of current literature sourced from PubMed, the review highlights advancements in AI-driven biomarker detection, evaluates the potential benefits of a broader diagnostic approach, and addresses challenges related to model standardization and clinical integration. AI-enhanced LDCT screening shows significant promise in augmenting routine screenings, potentially advancing early detection, comprehensive patient assessments, and overall disease management across multiple health conditions.…”
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Designing CITOBOT: A portable device for cervical cancer screening using human-centered design, smart prototyping, and artificial intelligence
Published 2024-12-01“…Additionally, we developed AI algorithms using the Inception V3 network, optimized with Transfer Learning and Fine Tuning, for cervical image classification and offline-operating software that guides the physician through the examination and provides a risk assessment for cervical cancer. …”
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254
Evaluation Algorithm of Ecological Energy-Saving Effect of Green Buildings Based on Gray Correlation Degree
Published 2021-01-01“…The environmental protection attribute and energy-saving level of green buildings cannot be described by the traditional evaluation model. In order to solve the above problems, a new ecological energy-saving effect evaluation algorithm of green buildings based on gray correlation degree is designed. …”
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Ensemble Algorithm Based on Gene Selection, Data Augmentation, and Boosting Approaches for Ovarian Cancer Classification
Published 2024-12-01“…<b>Results:</b> The target genes were screened and combined with data augmentation and ensemble boosting algorithms. …”
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256
Mathematical Background and Algorithms of a Collection of Android Apps for a Google Play Store Page
Published 2025-04-01“…All applications are fundamentally based on mathematical modeling and algorithmic effectiveness, emphasizing computational approaches over implementation specifics.…”
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Evolution of Algorithms and Applications for Unmanned Surface Vehicles in the Context of Small Craft: A Systematic Review
Published 2024-10-01“…In the categories application sector, autonomy level, application area and algorithm type/task, it was identified that most studies are oriented toward the maritime sector, the developments to achieve full autonomy for USVs, the development of designs or algorithms at the modeling and simulation level, and the development and implementation of algorithms for the GNC subsystems. …”
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PhyIndBC: Development of a machine learning tool for screening of potential breast cancer inhibitors from phytochemicalsGitHub
Published 2025-06-01“…Multiple ML techniques viz., k-nearest neighbor (KNN), random forest (RF), support vector machine (SVM), and extreme gradient boosting (XGB) were combined with various molecular fingerprints (MACCS and Morgan2) to develop multiple predictive models. Among these models, the RF algorithm coupled with the MACCS fingerprint emerged as the best performing model. …”
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Automated detection of hard exudates in retinal fundus images for diabetic retinopathy screening using textural-based radon transform and morphology reconstruction
Published 2025-06-01“…Background: Diabetic retinopathy (DR) screening requires accurate detection of hard exudates (HEs) in retinal images. …”
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Identification and Validation of NK Marker Genes in Ovarian Cancer by scRNA-seq Combined with WGCNA Algorithm
Published 2023-01-01“…The LASSO-COX algorithm was employed to build risk models to predict prognosis. …”
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