A Comprehensive Approach to Rustc Optimization Vulnerability Detection in Industrial Control Systems by Kaifeng Xie, Jinjing Wan, Lifeng Chen, Yi Wang

“…This paper proposes a test case generation method based on large language models (LLMs), which utilizes prompt templates and optimization algorithms to generate a code relevant to specific optimization passes, especially for real-time control logic and safety-critical modules unique to the industrial control field. …”
Get full text

Progress on the application of supercomputer brain simulation technology by SUN Zhe

“…This review examines the theoretical principles and technical foundations of supercomputer brain simulation, including distributed parallel algorithms, graphics processing unit (GPU)⁃based acceleration, and multimodal data management. …”
Get full text

Gaussian Process Regression and Machine Learning Methods for Carbon-Based Material Adsorption by Manar Ahmed Hamza, Maha M. Althobaiti, Fahd N. Al-Wesabi, Rana Alabdan, Hany Mahgoub, Anwer Mustafa Hilal, Abdelwahed Motwakel, Mesfer Al Duhayyim

“…., warmth, solution pH) and adsorbent varieties, the created Ml algorithms outperformed classic isotherm models in conditions of generalisation. …”
Get full text

Improving synergistic drug combination prediction with signature-based gene expression features in oncology by Mozhgan Mozaffarilegha, Sajjad Gharaghani

“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
Get full text

Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Multiple analytical algorithms indicated that SLCs were associated with immune cell infiltration and immune checkpoint gene expression. …”
Get full text

Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis by Ma J, Li W, Ma Q, Ding L, Wang Z, Wang R, Huang Y, Ma G, Gao J

“…Jie Ma,1,2,* Wendi Li,3 Qianqian Ma,1 Liying Ding,4 Zhaoyun Wang,1 Rong Wang,1 Yanan Huang,1 Gang Ma,2,* Jun Gao1,* 1Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China; 3Department of Child Rehabilitation Education, Ningxia Rehabilitation Center for the Disabled, Yinchuan, Ningxia, 750002, People’s Republic of China; 4Department of Gynecology, Gynecology Clinic of Li Ying, Wuzhong, Ningxia, 751100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gang Ma, Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China, Email magang2671@163.com Jun Gao, Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China, Email gaojun1605@sina.comIntroduction: This study aimed to identify diagnostic and therapeutic biomarkers related to glucose metabolism in sepsis, as hyperglycemia and blood glucose fluctuations influence sepsis progression.Methods: Datasets from public databases were analyzed using various methods, including differential expression analysis, PPI network screening, machine learning algorithms and Mendelian randomization. …”
Get full text

Long-term risk of de novo malignancy with tumor necrosis factor alpha (TNF) inhibitor immunosuppression: a multicenter, retrospective cohort study by Conor B. Driscoll, Jordan M. Rich, Christopher Yang, Joseph Nicolas, Dylan Isaacson, Philip Silberman, Xinlei Mi, Sai Kaushik Shakar Ramesh Kumar, Hui Zhang, Steven Belknap, William H. Temps, Edward M. Schaeffer, Shilajit D. Kundu

“…There may need to be differential cancer screening algorithms for patients with different inflammatory conditions and TNF-I exposure.…”
Get full text

Integrating health equity in artificial intelligence for public health in Canada: a rapid narrative review by Samantha Ghanem, Marielle Moraleja, Danielle Gravesande, Jennifer Rooney

“…Several health equity considerations for applying AI in public health were identified, including gaps in AI epistemology, algorithmic bias, accessibility of AI technologies, ethical and privacy concerns, unrepresentative training datasets, lack of transparency and interpretability of AI models, and challenges in scaling technical skills.ConclusionWhile AI has the potential to advance public health in Canada, addressing equity is critical to preventing inequities. …”
Get full text

Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1 by Tingting Liu, Tingting Pan, Mingxin Chang, Shaojie Fu, Hongzhao Xu, Hao Wu, Zhonggao Xu, Yanli Cheng

“…Among them, dual specificity phosphatase 1 (DUSP1) was screened as FFG by three machine learning algorithms. …”
Get full text

Identifying neural substrates of competitive interactions and sequence transitions during mechanosensory responses in Drosophila. by Jean-Baptiste Masson, François Laurent, Albert Cardona, Chloé Barré, Nicolas Skatchkovsky, Marta Zlatic, Tihana Jovanic

Get full text

Enrollment and Retention Outcomes from the Veterans Health Administration for a Remote Digital Health Study: Multisite Observational Study by Jaclyn A Pagliaro, Lauren K Wash, Ka Ly, Jenny Mathew, Alison Leibowitz, Ryan Cabrera, Jolie B Wormwood, Varsha G Vimalananda

“…ResultsOf the 7714 who were mailed a study invitation, 560 were screened. Of the screened patients, 203 were enrolled (2.9% enrollment yield) and 166 completed the study (82% retention rate). …”
Get full text

Association between impaired sensitivity to thyroid hormones and sedentary behavior: a cross-sectional study by Hangzhou Yang, Jie Kang, Lingkang Dong, Zihan Lin, Qixian Lin, Bo Wu

“…The Least Absolute Shrinkage and Selection Operator (LASSO) regression and the Boruta algorithm were employed to screen out confounding factors closely associated with sedentary time and the parametric thyroid feedback quantile-based index (PTFQI). …”
Get full text

Relationship between stress hyperglycemia ratio and the incidence of atrial fibrillation in patients after coronary artery bypass grafting: a retrospective study based on the MIMIC... by Runjia Liu, Jiatong Li, Jing Zeng, Yuxuan Tao, Dong Chen, Haixia Li

“…We employed logistic regression models, restricted cubic splines (RCS), threshold effect analysis, ubgroup analysis, Boruta algorithm, lasso algorithm, and receiver operating characteristics (ROC) to analyze the relationship between SHR and POAF incidence comprehensively. …”
Get full text

PRKDC regulates cGAMP to enhance immune response in lung cancer treatment by Zhanghao Huang, Zhanghao Huang, Zhanghao Huang, Runqi Huang, Runqi Huang, Runqi Huang, Jun Zhu, Jun Zhu, Youlang Zhou, Youlang Zhou, Jiahai Shi, Jiahai Shi

“…This study aimed to investigate the antitumor effects of 2’,3’-cGAMP in LUAD.MethodHerein, patients with LUAD were screened for prognostic biomarkers, which were then assessed for sensitivity to immunotherapy and chemotherapy utilizing the “TIDE” algorithm and CellMiner database. …”
Get full text

Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Lea... by Xiao S, Ding Y, Du C, Lv Y, Yang S, Zheng Q, Wang Z, Zheng Q, Huang M, Xiao Q, Ren Z, Bi G, Yang J

“…Subsequently, the hub genes were identified by Lasso and Cytoscape with three machine-learning algorithms (MCC, Degree and MCODE). In addition, hub genes were validated with ROC, single-cell sequence and IHC in hyperoxia mice. …”
Get full text

Association between the development of sepsis and the triglyceride-glucose index in acute pancreatitis patients: a retrospective investigation utilizing the MIMIC-IV database by Lin Xu, Xuejing Li, Na Zhang, Chunmei Guo, Pan Wang, Min Gao, Yanhui Zhang, Lixin Zhao

“…Utilizing the formula ln[(triglycerides mg/dl) × (glucose mg/dl)/2], the TyG index was calculated. The Boruta algorithm and Xgboost model were used for feature selection in order to pinpoint the important variables affecting results. …”
Get full text

Integrating Artificial Intelligence and Microfluidics Technology for Psoriasis Therapy: A Comprehensive Review for Research and Clinical Applications by Ibrahim Shaw, Yimer Seid Ali, Changhong Nie, Kexin Zhang, Chuanpin Chen, Yin Xiao

“…Integrating artificial intelligence (AI) with microfluidics promises to overcome these barriers by leveraging AI algorithms to automate device design, streamline experimentation, and enhance diagnostic and therapeutic outcomes. …”
Get full text

Big data transfer service architecture for cloud data centers: problems, methods, applications, and future trends by Muhammad Umar Majigi, Ismaila Idris, Shafi’i Muhammad Abdulhamid, Richard A. Ikuesan

“…Key issues identified in the context of big data transfer services for cloud data centers include storage, big data transfer, service transfer architecture, data processing, bandwidth, and security, all of which demand extensive research. After thoroughly screening selected peer-reviewed articles, the primary open issues are: incorporating a data placement module in the data transfer service, providing end-to-end safeguards for packet delivery, improving data transfer time and speed, minimizing costs and implementation overhead, ensuring secure data transfer between servers in the cloud, demonstrating effective big data transfer architectures, considering topology-specific extensions to reduce the busty nature of data centers, and enhancing data transfer services using machine learning algorithms during upload and download operations. …”
Get full text

Graph neural processes for molecules: an evaluation on docking scores and strategies to improve generalization by Miguel García-Ortegón, Srijit Seal, Carl Rasmussen, Andreas Bender, Sergio Bacallado

“…We evaluate their performance on regression and optimization molecular tasks using docking scores, finding them to outperform classical single-task and transfer-learning models. We examine the issue of generalization to divergent test tasks, which is a general concern of meta-learning algorithms in science, and propose strategies to alleviate it.…”
Get full text

Biophysical and nutritional combination treatment for myosteatosis in patients with sarcopenia: a study protocol for single-blinded randomised controlled trial by Maoyi Tian, Ling Qin, Simon Kwoon Ho Chow, Wing Hoi Cheung, A A Welch, Can Cui, Parco M Siu, Meng Chen Michelle Li, Yu Kin Cheng, Ronald Man Yeung Wong, Timothy CY Kwok, Minghui Yang, Clinton Rubin, Sheung Wai Law

“…The findings of this study will demonstrate the effect of combination treatment as an alternative for managing sarcopenia.Methods and analysis In this single-blinded randomised controlled trial, subjects will be screened based on the Asian Working Group for Sarcopenia (AWGS) 2019 definition. 200 subjects who are aged 65 or above and identified sarcopenic according to the AWGS algorithm will be recruited. …”
Get full text