Assessing the predictive value of time-in-range level for the risk of postoperative infection in patients with type 2 diabetes: a cohort study by Ying Wu, Rui Xv, Qinyun Chen, Ranran Zhang, Min Li, Chen Shao, Guoxi Jin, Guoxi Jin, Xiaolei Hu, Xiaolei Hu

“…LASSO regression and the Boruta algorithm were used to screen out the predictive factors related to postoperative infection in T2DM patients in the training set. …”
Get full text

Development and validation of a machine learning-based prediction model for hepatorenal syndrome in liver cirrhosis patients using MIMIC-IV and eICU databases by Fengwei Yao, Ji Luo, Qian Zhou, Luhua Wang, Zhijun He

“…By integrating the MIMIC-IV database and machine learning algorithms, we developed an effective predictive model for HRS in liver cirrhosis patients, providing a robust tool for early clinical intervention.…”
Get full text

Prospective external validation of the automated PIPRA multivariable prediction model for postoperative delirium on real-world data from a consecutive cohort of non-cardiac surgery... by Mary-Anne Kedda, Kelly A Reeve, Nayeli Schmutz Gelsomino, Michela Venturini, Felix Buddeberg, Martin Zozman, Reto Stocker, Philipp Meier, Marius Möller, Simone Pascale Wildhaber, Benjamin T Dodsworth

“…The study highlighted the model’s applicability across diverse clinical environments, despite differences in patient populations and screening protocols.Conclusions The PIPRA algorithm is a reliable tool for identifying surgical patients at risk of POD, supporting early intervention strategies to improve patient outcomes. …”
Get full text

Categorizing Mental Stress: A Consistency-Focused Benchmarking of ML and DL Models for Multi-Label, Multi-Class Classification via Taxonomy-Driven NLP Techniques by Juswin Sajan John, Boppuru Rudra Prathap, Gyanesh Gupta, Jaivanth Melanaturu

“…Building on existing literature, discussions with psychologists and other mental health practitioners, we developed a taxonomy of 27 distinctive markers spread across 4 label categories; aiming to create a preliminary screening tool leveraging textual data.The core objective is to identify the most suitable model for this complex task, encompassing comprehensive evaluation of various machine learning and deep learning algorithms. we experimented with support vector machines (SVM), random forest (RF) and long short-term memory (LSTM) algorithms incorporating various feature combinations involving Term Frequency-Inverse Document Frequency (TF-IDF) and Latent Dirichlet Allocation (LDA). …”
Get full text

Adaptive strategies for the deployment of rapid diagnostic tests for COVID-19: a modelling study [version 2; peer review: 2 approved, 1 approved with reservations] by Emily Kendall, Lucia Cilloni, Nimalan Arinaminpathy, David Dowdy

“…Concentrating on urban areas in low- and middle-income countries, the aim of this analysis was to estimate the degree to which ‘dynamic’ screening algorithms, that adjust the use of confirmatory polymerase chain reaction (PCR) testing based on epidemiological conditions, could reduce cost without substantially reducing the impact of testing. …”
Get full text

Using Life’s Essential 8 and heavy metal exposure to determine infertility risk in American women: a machine learning prediction model based on the SHAP method by Xiaoqing Gu, Qianbing Li, Xiangfei Wang

“…The association between LE8 and heavy metal exposure and risk of infertility was assessed using logistic regression analysis and six machine learning models (Decision Tree, GBDT, AdaBoost, LGBM, Logistic Regression, Random Forest), and the SHAP algorithm was used to explain the model’s decision process.ResultsOf the six machine learning models, the LGBM model has the best predictive performance, with an AUROC of 0.964 on the test set. …”
Get full text

Deep Learning-Based Detection of Aflatoxin B1 Contamination in Almonds Using Hyperspectral Imaging: A Focus on Optimized 3D Inception–ResNet Model by Md. Ahasan Kabir, Ivan Lee, Sang-Heon Lee

“…A feature selection algorithm was employed to enhance processing efficiency and reduce spectral dimensionality while maintaining high classification accuracy. …”
Get full text

Identification and validation of prognostic genes associated with T-cell exhaustion and macrophage polarization in breast cancer by Fengqiang Cui, Changjiao Yan, Jiang Wu, Yuqing Yang, Jixin Yang, Jialing Luo, Nanlin Li

“…Next, 101 combinations of 10 machine learning algorithms and univariate Cox analysis were utilized to screen for prognostic genes. …”
Get full text

AI-driven innovation in antibody-drug conjugate design by Heather A. Noriega, Xiang Simon Wang

“…This review is organized into six sections: (1) the progression from traditional modeling approaches to AI-driven design of individual ADC components; (2) the application of deep learning (DL) to antibody structure prediction and identification of optimal conjugation sites; (3) the use of AI/ML models for forecasting pharmacokinetic properties and toxicity profiles; (4) emerging generative algorithms for antibody sequence diversification and affinity optimization; (5) case studies demonstrating the integration of computational tools with experimental pipelines, including systems that link in silico predictions to high-throughput validation; and (6) persistent challenges, including data sparsity, model interpretability, validation complexity, and regulatory considerations. …”
Get full text

Construction of a machine learning-based risk prediction model for depression in middle-aged and elderly patients with cardiovascular metabolic diseases in China: a longitudinal st... by Gege Zhang, Sijie Dong, Li Wang

“…LASSO regression was used to screen for risk factors, and three machine learning algorithms—logistic regression (LR), random forest (RF), and XGBoost—were employed to build predictive models. …”
Get full text

Development of a postoperative recurrence prediction model for stage Ⅰ non-small cell lung cancer patients using multimodal data based on machine learning by ZHANG Di, WU Yi, XU Yu

“…A combined model was further constructed by integrating both feature sets, and model performance was compared to identify the optimal predictive model.Results‍　‍This study screened the features from non-contrast CT images and ultimately selected 7 radiomic features for constructing radiomic model. …”
Get full text

Translational medicine research on the role of key gene network modulation mediated by procyanidin B2 in the precise diagnosis and treatment of multiple sclerosis by Jian Liu, Meng Pu, Di Guo, Ying Xiao, Jin-zhu Yin, Dong Ma, Cun-gen Ma, Qing Wang

“…Eight machine learning algorithms were employed to screen key genes, and nomograms and ROC curves were constructed to assess the value of the screened biomarker genes in MS diagnosis. …”
Get full text

Construction of a Prediction Model for Sleep Quality in Embryo Repeated Implantation Failure Patients Undergoing Assisted Reproductive Technology Based on Machine Learning: A Singl... by Zhao Y, Xu C, Qin N, Bai L, Wang X, Wang K

“…Use Lasso regression to screen variables and construct a risk prediction model using six machine learning algorithms. …”
Get full text

Predicting onset of myopic refractive error in children using machine learning on routine pediatric eye examinations only by Yonina Ron, Tchelet Ron, Naomi Fridman, Anat Goldstein

“…This study develops machine learning (ML) models to predict future myopia development. These models utilize easily accessible, non-invasive data gathered during standard eye clinic visits, deliberately excluding more complex measurements such as axial length or corneal curvature. …”
Get full text

Open-Circuit Fault Diagnosis Method of Energy Storage Converter Based on MFCC Feature Set by Bin YU, Xingrong SONG, Ting ZHOU, Linbo LUO, Hui LI, Liang CHE

“…Secondly, a fault state diagnosis model based on the Bayesian optimization algorithm (BOA) and one-dimensional convolutional neural network (CNN-1D) is constructed with a low-dimensional fault feature set as an input. …”
Get full text

Multi-model machine learning framework for lung cancer risk prediction: A comparative analysis of nine classifiers with hybrid and ensemble approaches using behavioral and hematolo... by Vinod Kumar, Chander prabha, Deepali Gupta, Sapna Juneja, Swati Kumari, Ali Nauman

“…The present study investigates 34 demographic, behavioral, and hematological risk factors based on a sample of 2,000 patient data records. A multi-model machine learning approach compares nine algorithms: KNN, AdaBoost (AB), logistic regression (LR), random forest (RF), SVM, naive Bayes (NB), decision tree (DT), gradient boosting (GB), and stochastic gradient descent (SGD). …”
Get full text

Evaluating Leaf Water Potential of Maize Through Multi-Cultivar Dehydration Experiments and Segmentation Thresholding by Shuanghui Zhao, Yanqun Zhang, Pancen Feng, Xinlong Hu, Yan Mo, Hao Li, Jiusheng Li

“…In this study, leaf dehydration experiments of three maize cultivars were applied to provide a dataset covering a wide range of <i>Ψ_leaf</i> variations, which is often challenging to obtain in field trials. The analysis screened published VIs highly correlated with <i>Ψ_leaf</i> and constructed a model for <i>Ψ_leaf</i> estimation based on three algorithms—partial least squares regression (PLSR), random forest (RF), and multiple linear stepwise regression (MLR)—for each cultivar and all three cultivars. …”
Get full text

Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer by Yanliang Chen, Chan Zhou, Xiaoqiao Zhang, Min Chen, Meifang Wang, Lisha Zhang, Yanhui Chen, Litao Huang, Junjun Sun, Dandan Wang, Yong Chen

“…The least absolute shrinkage and selection operator (LASSO) regression and random survival forest (RSF) were used to screen for prognostically relevant RRRGs. Multivariate Cox regression was used to construct a risk score model. …”
Get full text

Machine vision-based detection of key traits in shiitake mushroom caps by Jiuxiao Zhao, Jiuxiao Zhao, Wengang Zheng, Wengang Zheng, Yibo Wei, Yibo Wei, Qian Zhao, Qian Zhao, Jing Dong, Jing Dong, Xin Zhang, Xin Zhang, Mingfei Wang, Mingfei Wang

“…Finally,M3 group using GWO_SVM algorithm achieved optimal performance among six mainstream machine learning models tested with an R²value of 0.97 and RMSE only at 0.038 when comparing predicted values with true values. …”
Get full text

HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…Multiple structure-based artificial intelligence (AI) binary classifiers for predicting hERG inhibitors were developed, employing, as descriptors, protein–ligand extended connectivity (PLEC) fingerprints fed into random forest, extreme gradient boosting, and deep neural network (DNN) algorithms. Our best-performing model, a stacking ensemble classifier with a DNN meta-learner, achieved state-of-the-art classification performance, accurately identifying 86% of molecules having half-maximal inhibitory concentrations (IC50s) not exceeding 20 µM in our challenging test set, including 94% of hERG blockers whose IC50s were not greater than 1 µM. …”
Get full text