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Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective stu...
Published 2025-07-01“…Internal validation employed ROC analysis and calibration curves, while Shapley Additive Explanations (SHAP) values interpreted feature importance in the optimal model.ResultsAmong 2,921 screened patients, 1,272 met inclusion criteria. …”
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1322
人工智能融合临床与多组学数据在卒中防治及医药研发中的应用与挑战Applications and Challenges of Integrating Artificial Intelligence with Clinical and Multi-omics Data in Stroke Prevention, Treatment, and Pharmaceut...
Published 2025-06-01“…By integrating and analyzing clinical and multi-omics data, AI technology enhances the identification of high-risk populations, optimizes early diagnosis and risk assessment, enables precise subtyping of stroke, facilitates the screening of potential drug targets, and constructs prognostic prediction models. …”
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1323
Development and validation of a nomogram for predicting in-hospital mortality in older adult hip fracture patients with atrial fibrillation: a retrospective study
Published 2025-07-01“…Logistic regression (LR) and Least Absolute Shrinkage and Selection Operator (LASSO) algorithms were employed to screen features. We further used Extreme Gradient Boosting (XGBoost) based on features selected by LR and LASSO algorithms to assist in identifying the final model-established features. …”
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1324
Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
Published 2025-02-01“…We integrated the genes screened by three machine learning models (LASSO, SVM, and Random Forest), and CXCR4 was identified as a key gene with potential therapeutic value in DFUs. …”
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1325
Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target
Published 2025-08-01“…Using differential expression analysis and machine learning algorithms, 12 potential hub genes were successfully screened. …”
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1326
Harnessing AI and Quantum Computing for Revolutionizing Drug Discovery and Approval Processes: Case Example for Collagen Toxicity
Published 2025-07-01“…In this context, “in silico” describes scientific studies performed using computer algorithms, simulations, or digital models to analyze biological, chemical, or physical processes without the need for laboratory (in vitro) or live (in vivo) experiments. …”
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1327
Identification and analysis of neutrophil extracellular trap-related genes in periodontitis via bioinformatics and experimental verification
Published 2025-08-01“…Then, machine learning algorithms were exploited to screen hub NRGs, and a predictive model was constructed based on these hub NRGs. …”
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1328
Design, Fabrication, and Application of Large-Area Flexible Pressure and Strain Sensor Arrays: A Review
Published 2025-03-01“…The rapid development of flexible sensor technology has made flexible sensor arrays a key research area in various applications due to their exceptional flexibility, wearability, and large-area-sensing capabilities. …”
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1329
Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome
Published 2025-07-01“…The risk score model constructed based on these biomarkers could effectively predict the survival rate of cervical cancer patients (AUC >0.6 for 1/3/5 years). …”
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1330
Research on the Evaluation of the Node Cities of China Railway Express Based on Machine Learning
Published 2025-06-01“…The Random Forest model outperformed comparative algorithms with 99.5% prediction accuracy (8.33% higher than conventional classification models), particularly in handling multi-dimensional interactions between urban development factors. …”
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1331
Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes.
Published 2024-01-01“…According to the five machine algorithms, 4 features (S100A2, GNGT1, NEUROD4, FCN2) were screened and used to create a PD diagnostic model. …”
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1332
Maximizing YOLOv2 efficiency: A study on multiclass detection of indoor objects
Published 2025-06-01“…The objective of the present study is to present a systematic approach for optimizing the key hyperparameters of YOLOv2 model for multiclass object detection, specifically targeting seven classes of indoor objects: chair, fire extinguisher, printer, screen, trash bin, exit, and clock. …”
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1333
Use of artificial intelligence to support prehospital traumatic injury care: A scoping review
Published 2024-10-01“…Conclusions A small but growing body of literature described AI models based on prehospital features that may support decisions made by dispatchers, Emergency Medical Services clinicians, and trauma teams in early traumatic injury care.…”
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1334
SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses
Published 2025-08-01“…A SUMOylation Risk Score (SRS) model was developed using 69 machine learning models across 10 algorithms, with performance evaluated by C-index and AUC. …”
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1335
Estimation of the water content of needles under stress by Erannis jacobsoni Djak. via Sentinel-2 satellite remote sensing
Published 2025-04-01“…Multiple vegetation indices are screened via recursive feature elimination cross validation (RFECV), and then support vector regression (SVR) and back-propagation neural network (BP) models are used to predict the leaf weight content fresh (LWCF) and leaf weight content dry (LWCD) of needles over a large area. …”
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1336
Exploring the predictive values of CRP and lymphocytes in coronary artery disease based on a machine learning and Mendelian randomization
Published 2024-09-01“…Techniques employed included propensity score matching (PSM), logistic regression, lasso regression, and random forest algorithms (RF). Risk factors were assessed, and the sensitivity and specificity of the models were evaluated using receiver operating characteristic (ROC) curves. …”
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1337
Identification of hub genes for the diagnosis associated with heart failure using multiple cell death patterns
Published 2025-08-01“…Bioinformatics and machine learning algorithms were utilized to screen the HF key genes and PCD‐related HF hub genes, and an HF diagnostic model was constructed on this. …”
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1338
Unveiling the ageing-related genes in diagnosing osteoarthritis with metabolic syndrome by integrated bioinformatics analysis and machine learning
Published 2025-12-01“…The limma package was used to identify differentially expressed genes (DEGs), and weighted gene coexpression network analysis (WGCNA) screened gene modules, and machine learning algorithms, such as random forest (RF), support vector machine (SVM), generalised linear model (GLM), and extreme gradient boosting (XGB), were employed. …”
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1339
Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study
Published 2025-07-01“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer
Published 2025-01-01“…Utilizing three distinct machine learning algorithms, we identified three signature genes-PBX1, IGHM, and CXCL13-that exhibited significant diagnostic value within the diagnostic model. …”
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