Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research by Fan Jiang, Fan Jiang, Fan Jiang, Yanhua Liu, Linsheng Li, Linsheng Li, Ruizi Ni, Ruizi Ni, Yajing An, Yajing An, Yufeng Li, Yufeng Li, Lingxia Zhang, Wenping Gong

“…A Naive Bayes (NB) model incorporating these two markers demonstrated robust diagnostic performance: training set AUC: median = 0.8572 (inter-quartile range 0.8002, 0.8708), validation AUC = 0.5719 (0.51645, 0.7078), and subgroup AUC = 0.8635 (0.8212, 0.8946).ConclusionOur multicohort analysis established an NB-based diagnostic model utilizing S100A12/S100A8, which maintains diagnostic accuracy across diverse geographic, ethnic, and clinical variables (including HIV co-infection), highlighting its potential for clinical translation in LTBI/ATB differentiation.…”
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Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning by Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang

“…Results Six hub genes related to CRs (CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI) were screened out. Immune infiltration analysis revealed that the IVDD group had significantly more M0 macrophages and significantly fewer follicular helper T cells than those of the control group. …”
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AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen by Zhen Gao, Qiyuan Bai, Mingyu Wei, Hao Chen, Yan Yan, Jiahao Mao, Xiangzhi Kong, Yang Yu

“…Conclusions: Using machine-learning algorithms, we built a prediction model of a treatment plan for patients with concomitant DM and CHD by integrating patients' information and screened the best feature set containing 15 features, which provides help and strategies to develop the best treatment plan for patients with concomitant DM and CHD.…”
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Low-cost and scalable machine learning model for identifying children and adolescents with poor oral health using survey data: An empirical study in Portugal. by Susana Lavado, Eduardo Costa, Niclas F Sturm, Johannes S Tafferner, Octávio Rodrigues, Pedro Pita Barros, Leid Zejnilovic

“…Such a model could enable scalable and cost-effective screening and targeted interventions, optimizing limited resources to improve oral health outcomes. …”
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A novel prediction model for the prognosis of non-small cell lung cancer with clinical routine laboratory indicators: a machine learning approach by Yuli Wang, Na Mei, Ziyi Zhou, Yuan Fang, Jiacheng Lin, Fanchen Zhao, Zhihong Fang, Yan Li

“…Finally, critical variables in the optimal model were screened based on the interpretable algorithms to build a decision tree to facilitate clinical application. …”
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The Automatable Activity–Based Approach to Complexity Unit Scoring as a task-specific model approach to monetizing outcomes of pathology artificial intelligence solutions by Stavros Pantelakos, Martha Nifora, Georgios Agrogiannis

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An efficient hybrid Hopfield convolutional neural network for detecting spam bots in Twitter platform by A.V. Santhosh Kumar, N. Suresh Kumar, R. Kanniga Devi

“…The extracted features are then subjected to feature selection, where a meta-heuristic-based optimization algorithm called the Binary Golden Search Optimization algorithm (BGSO) is used. …”
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A Dual-Variable Selection Framework for Enhancing Forest Aboveground Biomass Estimation via Multi-Source Remote Sensing by Dapeng Chen, Hongbin Luo, Zhi Liu, Jie Pan, Yong Wu, Er Wang, Chi Lu, Lei Wang, Weibin Wang, Guanglong Ou

“…The dual-variable selection strategy integrates SHAP with the Pearson correlation coefficient (PC), RF, EN, and Lasso to enhance feature screening robustness and interpretability. The results of the study showed that Lasso-SHAP dual-variate screening was more stable than SHAP univariate screening. …”
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Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity by Shan Jin, Junbin Yin, Wei Li, Ni Mao

“…Multiple machine learning algorithms were applied to screen and verify the diagnostic genes of intersection genes. …”
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Development and validation of an early predictive model for hemiplegic shoulder pain: a comparative study of logistic regression, support vector machine, and random forest by Qiang Wu, Qiang Wu, Fang Zhang, Yuchang Fei, Zhenfen Sima, Shanshan Gong, Qifeng Tong, Qingchuan Jiao, Hao Wu, Jianqiu Gong, Jianqiu Gong

“…ObjectiveIn this study, we aim to identify the predictive variables for hemiplegic shoulder pain (HSP) through machine learning algorithms, select the optimal model and predict the occurrence of HSP.MethodsData of 332 stroke patients admitted to a tertiary hospital in Zhejiang Province from January 2022 to January 2023 were collected. …”
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Machine Learning-Assisted NIR Spectroscopy for Dynamic Monitoring of Leaf Potassium in Korla Fragrant Pear by Mingyang Yu, Weifan Fan, Junkai Zeng, Yang Li, Lanfei Wang, Hao Wang, Feng Han, Jianping Bao

“…By measuring leaf potassium content at the fruit setting, expansion, and maturity stages (decreasing from 1.60% at fruit setting to 1.14% at maturity), this study reveals its dynamic change pattern and establishes a high-precision prediction model by combining near-infrared spectroscopy (NIRS) with machine learning algorithms. …”
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Exploring patterns in pediatric type 1 diabetes care and the impact of socioeconomic status by Christopher Nussbaum, Anna Novelli, Amelie Flothow, Leonie Sundmacher

“…Higher socioeconomic status is associated with care that more closely adheres to clinical guidelines.…”
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Comparative analysis of machine learning models for malaria detection using validated synthetic data: a cost-sensitive approach with clinical domain knowledge integration by Gudi V. Chandra Sekhar, Chekol Alemu

“…Machine learning offers promising solutions for automated detection, but systematic algorithm comparison using clinically validated data remains limited. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…A discriminative diagnostic model was developed using a multivariate logistic regression algorithm. …”
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Plasma proteomics-based risk scores for psoriasis prediction: a novel approach to early diagnosis by Siyu Wei, Zehong Yue, Chen Sun, Yuping Zou, Haiyan Chen, Junxian Tao, Jing Xu, Yuan Xu, Ning Wang, Yan Guo, Qinduo Ren, Chang Wang, Songlin Lu, Ye Ma, Yu Dong, Chen Zhang, Hongmei Sun, Guoping Tang, Fanwu Kong, Wenhua Lv, Zhenwei Shang, Mingming Zhang, Yongshuai Jiang, Hongchao Lyu

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Molecular characterization and prognostic modeling associated with M2-like tumor-associated macrophages in breast cancer: revealing the immunosuppressive role of DLG3 by Ziqiang Wang, Jing Zhang, Huili Chen, Xinyu Zhang, Kai Zhang, Feiyue Zhang, Yiluo Xie, Hongyu Ma, Linfeng Pan, Qiang Zhang, Min Lu, Hongtao Wang, Chaoqun Lian

“…Consensus clustering analysis identified three molecular subtypes with distinct clinical features, and we explored potential differences in genomic mutations, pathway enrichment, and immune infiltration in patients between subtypes. Machine learning algorithms were used to screen key genes and construct M2-like macrophage-associated prognostic models. …”
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Construction of an oligometastatic prediction model for nasopharyngeal carcinoma patients based on pathomics features and dynamic multi-swarm particle swarm optimization support ve... by Yunfei Li, Dongni Zhang, Yiren Wang, Yiren Wang, Yiheng Hu, Zhongjian Wen, Zhongjian Wen, Cheng Yang, Ping Zhou, Wen-Hui Cheng

“…A demo of the DMS-PSO-SVM modeling algorithm code used in this study can be found on Github (https://github.com/Edward-E-S-Wang/DMS-PSO-SVM).…”
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The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma by Fuqing Chen, Yifan Cai, Xiangmei Chen, Changzhou Chen, Qinliang Fang, Jianming Liu, Yibin Zhang, Jianyin Zhou

“…SVM algorithm was used to classify HCC patients based on HSCRGs. …”
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Non-Invasive Detection of Breast Cancer by Low-Coverage Whole-Genome Sequencing from Plasma by Li Peng, Ru Yao, Sihang Gao, Yang Qu, Li Qu, Jingbo Zhang, Yidong Zhou

“…Our approach adopted principal component analysis and a generalized linear model algorithm to distinguish between breast cancer and normal samples. …”
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Multimodal data integration with machine learning for predicting PARP inhibitor efficacy and prognosis in ovarian cancer by Xi’an Xiong, Li Cai, Li Cai, Zhen Yang, Zhongping Cao, Nayiyuan Wu, Nayiyuan Wu, Qianxi Ni

“…Patient-specific efficacy and prognosis prediction models were then constructed using various machine learning algorithms.ResultsTotal bile acids (TBAs) and CA-199 present as an independent risk factor in Cox multivariate analysis for primary and recurrent ovarian cancer patients respectively (P < 0.05). …”
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