Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for thyroid cancer by Peng Zhang, Meizhong Qin, Fen Li, Kunpeng Hu, He Huang, Cuicui Li

“…Abstract Background Thyroid cancer (THCA) exhibits high molecular heterogeneity, posing challenges for precise prognosis and personalized therapy. Most existing models rely on single-omics data and limited algorithms, reducing robustness and clinical value. …”
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To accurately predict lymph node metastasis in patients with mass-forming intrahepatic cholangiocarcinoma by using CT radiomics features of tumor habitat subregions by Pengyu Chen, Zhenwei Yang, Peigang Ning, Hao Yuan, Zuochao Qi, Qingshan Li, Bo Meng, Xianzhou Zhang, Haibo Yu

“…Using information from the arterial and venous phases of multisequence CT images, tumor habitat subregions were delineated through the K-means clustering algorithm. Radiomic features were extracted and screened, and prediction models based on different subregions were constructed and compared with traditional intratumoral models. …”
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Spectral estimation of the aboveground biomass of cotton under water–nitrogen coupling conditions by Shunyu Qiao, Jiaqiang Wang, Fuqing Li, Jing Shi, Chongfa Cai

“…Through correlation analysis between cotton AGB and canopy spectral reflectance, the intersection of feature wavelengths screened by the successive projection algorithm (SPA) and highly significant wavelengths was used as the input vector for modeling. …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…After univariate Cox analysis, prognostic genes were carried out for modeling mitochondria signature (MS) based on 101 combinations of 10 machine learning algorithms. …”
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Predicting radiation pneumonitis in lung cancer using machine learning and multimodal features: a systematic review and meta-analysis of diagnostic accuracy by Zhi Chen, GuangMing Yi, XinYan Li, Bo Yi, XiaoHui Bao, Yin Zhang, XiaoYue Zhang, ZhenZhou Yang, Zhengjun Guo

“…By selecting multiple machine learning algorithm frameworks and competing for the best combination model based on research goals, the reliability and accuracy of the radiation pneumonitis prediction model can be greatly improved. …”
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Remote clinical decision support tool for Parkinson’s disease assessment using a novel approach that combines AI and clinical knowledge by Harel Rom, Ori Peleg, Yovel Rom, Anat Mirelman, Gaddi Blumrosen, Inbal Maidan

“…Conclusions Our results demonstrate the feasibility of using advanced AI in a clinical decision support tool for PD diagnosis, suggesting a novel approach for home-based screening to identify PD patients. This method represents a significant innovation, transforming clinical knowledge into practical algorithms that can serve as effective screening tools. …”
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Identification and Evaluation of Lipocalin-2 in Sepsis-Associated Encephalopathy via Machine Learning Approaches by Hu J, Chen Z, Wang J, Xu A, Sun J, Xiao W, Yang M

“…Subsequently, neuroinflammation-related genes were obtained to construct a neuroinflammation-related signature. The AddModuleScore algorithm was used to calculate neuroinflammation scores for each cell subpopulation, whereas the CellCall algorithm was used to assess the crosstalk between neutrophils and other cell subpopulations. …”
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Emergency scheduling strategy of integrated electricity-gas energy system considering wind-power fluctuation in typhoon disaster by JIN Haixiang, BIAN Xiaoyan, HUANG Ruanming, ZHOU Qibin, XU Ling

“…The adaptive-alternating direction method of multipliers (AT-ADMM) algorithm is adopted to solve the model. An example is given to verify the effectiveness of the proposed method.…”
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Bioinformatics analysis of potential targets influencing the prognosis of OSCC by ZOU Xian, SONG Tao

“…The Timer website was used to analyze the relationship between hub genes and immune cell infiltration and immune checkpoints. Based on Lasso-Cox algorithm, a prognostic risk model of related genes was constructed. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…Abnormal liver functional tests were revealed in 30,6% of industrial city inhabitants — in 1461 of 4768 cases (232 patients were excluded from the study due to partial data loss), significantly more frequently in men in comparison to women, i.e. 49,7 and 25,5% respectively (p<0,001). …”
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Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. by Katherine R Bull, Andrew J Rimmer, Owen M Siggs, Lisa A Miosge, Carla M Roots, Anselm Enders, Edward M Bertram, Tanya L Crockford, Belinda Whittle, Paul K Potter, Michelle M Simon, Ann-Marie Mallon, Steve D M Brown, Bruce Beutler, Christopher C Goodnow, Gerton Lunter, Richard J Cornall

“…Forward genetics screens with N-ethyl-N-nitrosourea (ENU) provide a powerful way to illuminate gene function and generate mouse models of human disease; however, the identification of causative mutations remains a limiting step. …”
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Leveraging automated time-lapse microscopy coupled with deep learning to automate colony forming assay by Anusha Klett, Anusha Klett, Dennis Raith, Dennis Raith, Paula Silvestrini, Paula Silvestrini, Paula Silvestrini, Matías Stingl, Jonas Bermeitinger, Avani Sapre, Avani Sapre, Avani Sapre, Martin Condor, Roman Melachrinos, Mira Kusterer, Alexandra Brand, Guido Pisani, Guido Pisani, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Marie Follo, Marie Follo, Jesús Duque-Afonso, Roland Mertelsmann, Roland Mertelsmann

“…Brightfield images were used to train a YOLOv8 object detection network, achieving a mAP50 score of 86% for identifying single cells, clusters, and colonies, and 97% accuracy for Z-stack colony identification with a multi-object tracking algorithm. The detection model accurately identified the majority of objects in the dataset.ResultsThis AI-assisted CFA was successfully applied for density optimization, enabling the determination of seeding densities that maximize plating efficiency (PE), and for IC50 determination, offering an efficient, less labor-intensive method for testing drug concentrations. …”
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Adaptive Feature Selection of Unbalanced Data for Skiing Teaching by Tao Feng

“…If the features are not selected, the model may overly rely on the features of common actions and ignore the features of difficult actions. …”
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Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery by Ting Yan, Ting Su, Miaomiao Zhu, Qiyuan Qing, Binjie Huang, Jun Liu, Tenghui Ma

“…Subsequently, we performed Gene Ontology (GO) analysis and Kyoto encyclopedia of genes and genomes (KEGG) analyses, followed by immune infiltration analysis using the single-sample gene-set enrichment analysis (ssGSEA) and CIBERSORT algorithms. By constructing a multivariate Cox prognostic model using Kaplan–Meier curves and least absolute shrinkage and selection operator (LASSO) regression analysis, we assessed the model’s prognostic capability. …”
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Dynamic SOFA component scores-based deep learning for short to long-term mortality prediction in sepsis survivors by Juan Wei, Feihong Lin, Tian Jin, Qian Yao, Sheng Wang, Di Feng, Xin Lv, Wen He

“…We sought to feed common clinical available data to a deep learning algorithm for predicting short to long-term mortality in sepsis survivors. …”
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Research Progress and Prospect of Green Infrastructure with Public Health Promotion Function by Tongyu LI, Junyi LIXU, Binxia XUE, Yan (USA) SONG

“…To manage the multidimensionality of GI research, cluster analysis is performed using a Word2Vec model combined with a K-means algorithm to integrate different GI forms into a coherent classification system.ResultsThe results show that GI can be clearly divided into different categories, such as urban green spaces and parks, high-interaction spaces, trees in built-up areas, water management and biofiltration systems, community and residential greening, green roofs and facades, linear green networks, and broader macro-GI strategies. …”
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A study on early diagnosis for fracture non-union prediction using deep learning and bone morphometric parameters by Hui Yu, Qiyue Mu, Zhi Wang, Yu Guo, Jing Zhao, Guangpu Wang, Qingsong Wang, Xianghong Meng, Xiaoman Dong, Shuo Wang, Jinglai Sun

“…This study aims to create a fracture micro-CT image dataset, design a deep learning algorithm for fracture segmentation, and develop an early diagnosis model for fracture non-union.MethodsUsing fracture animal models, micro-CT images from 12 rats at various healing stages (days 1, 7, 14, 21, 28, and 35) were analyzed. …”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…A high IoU value in medical imaging analysis reflects the model’s ability to accurately delineate object boundaries.ConclusionDeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. …”
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Prevention of Cardiometabolic Syndrome in Children and Adolescents Using Machine Learning and Noninvasive Factors: The CASPIAN-V Study by Hamid Reza Marateb, Mahsa Mansourian, Amirhossein Koochekian, Mehdi Shirzadi, Shadi Zamani, Marjan Mansourian, Miquel Angel Mañanas, Roya Kelishadi

“…We applied the XGBoost algorithm to analyze key noninvasive variables, including self-rated health, sunlight exposure, screen time, consanguinity, healthy and unhealthy dietary habits, discretionary salt and sugar consumption, birthweight, and birth order, father and mother education, oral hygiene behavior, and family history of dyslipidemia, obesity, hypertension, and diabetes using five-fold cross-validation. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. …”
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