Immunoglobulin G N-Glycosylation and Inflammatory Factors: Analysis of Biomarkers for the Diagnosis of Moyamoya Disease by Zan X, Liu C, Wang X, Sun S, Li Z, Zhang W, Sun T, Hao J, Zhang L

“…This research aimed to evaluate the diagnostic efficacy of IgG N-glycosylation for MMD.Methods: Ultra-high-performance liquid chromatography (UPLC) was employed to examine the properties of IgG N-glycans in blood samples from 116 patients with MMD and 126 controls, resulting in the quantitative determination of 24 initial glycan peaks (GP). Through the Lasso algorithm and multivariate logistic regression analysis, we constructed a diagnostic model based on initial glycans and related inflammatory factors to distinguish MMD patients from healthy individuals.Results: After adjusting for potential confounding variables, including age, fasting blood glucose (FBG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), neutrophil count (NEUT), and lymphocyte count (LYM), our study demonstrated significant differences in the characteristics of 6 initial glycans and 16 derived glycans between the MMD cohort and the healthy control group. …”
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Predicting the risk of depression in older adults with disability using machine learning: an analysis based on CHARLS data by Tongtong Jin, Ayitijiang· Halili

“…This study systematically developed machine learning (ML) models to predict depression risk in disabled elderly individuals using longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS), providing a potentially generalizable tool for early screening.MethodsThis study utilized longitudinal data from the CHARLS 2011–2015 cohort. …”
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Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study by Ting Peng, Rujia Miao, Hao Xiong, Yanhui Lin, Duzhen Fan, Jiayi Ren, Jiangang Wang, Yuan Li, Jianwen Chen

“…In the test group, all AUC were also greater than 0.80. The LightGBM model showed the best IR prediction performance with an accuracy of 0.7542, sensitivity of 0.6639, specificity of 0.7642, F1 ConclusionBy leveraging low-cost laboratory indicators and questionnaire data, the LightGBM model effectively predicts IR status in nondiabetic individuals, aiding in large-scale IR screening and diabetes prevention, and it may potentially become an efficient and practical tool for insulin sensitivity assessment in these settings.…”
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Predicting Affinity Through Homology (PATH): Interpretable binding affinity prediction with persistent homology. by Yuxi Long, Bruce R Donald

“…Compared to current binding affinity prediction algorithms, PATH+ shows similar or better accuracy and is more generalizable across orthogonal datasets. …”
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Exploring timely and safe discharge from ICU: a comparative study of machine learning predictions and clinical practices by Chao Ping Wu, Rachel Benish Shirley, Alex Milinovich, Kaiyin Liu, Eduardo Mireles-Cabodevila, Hassan Khouli, Abhijit Duggal, Anirban Bhattacharyya

“…It also highlights ML models can serve as a promising screening tool to enhance ICU discharge, presenting a pathway toward more efficient and reliable critical care decision-making.…”
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A Cell Component-Related Prognostic Signature for Head and Neck Squamous Cell Carcinoma Based on the Tumor Microenvironment by Siyu Li, Yajun Gu, Junguo Wang, Dengbin Ma, Xiaoyun Qian, Xia Gao

“…In this study, we aimed to develop a cell component-related prognostic model based on TME. We screened cell component enrichments from samples in The Cancer Genome Atlas (TCGA) HNSCC cohort using the xCell algorithm. …”
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Predicting cardiotoxicity in drug development: A deep learning approach by Kaifeng Liu, Huizi Cui, Xiangyu Yu, Wannan Li, Weiwei Han

“…This study not only improved the predictive accuracy of cardiotoxicity models but also promoted a more reliable and scientifically interpretable method for drug safety assessment. …”
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Global trends in machine learning applications for single-cell transcriptomics research by Xinyu Liu, Zhen Zhang, Chao Tan, Yinquan Ai, Hao Liu, Yuan Li, Jin Yang, Yongyan Song

“…Research hotspots concentrated on random forest (RF) and deep learning models, showing transition from algorithm development to clinical applications (e.g., tumor immune microenvironment analysis). …”
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Mitochondrial-Localized Protein Transcript Abundance can Predict the Prognosis of Endometrial Carcinoma: A Retrospective Analysis by Weifei Liang, Hong Lin, Donglin Sun, Minghui Tang

“…Moreover, a nomogram was constructed through the combination of the scoring algorithm and the patient’s clinical features. Conclusions: The scoring algorithm based on mitochondrial gene expression can assist clinicians in predicting the postoperative survival rate of patients, allowing them to devise more precise treatment programs.…”
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Implementation costs and cost-effectiveness of ultraportable chest X-ray with artificial intelligence in active case finding for tuberculosis in Nigeria. by Tushar Garg, Stephen John, Suraj Abdulkarim, Adamu D Ahmed, Beatrice Kirubi, Md Toufiq Rahman, Emperor Ubochioma, Jacob Creswell

“…We provide implementation cost and cost-effectiveness estimates of different screening algorithms using symptoms, CXR and AI in Nigeria. …”
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An incremental data-driven approach for carbon emission prediction and optimization of heat treatment processes by Qian Yi, Xin Wu, Junkang Zhuo, Congbo Li, Chuanjiang Li, Huajun Cao

“…Using life cycle assessment (LCA) theory, carbon emission sources are accurately analyzed and quantified, and a full life cycle carbon emission model is established. The key process parameters affecting part performance and carbon emission were screened through mechanism analysis, and the incremental data were fused by the Elasticity Weight Consolidation (EWC) algorithm to establish an EWC-BPNN heat treatment carbon emission prediction model. …”
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Combinations of multimodal neuroimaging biomarkers and cognitive test scores to identify patients with cognitive impairment by Yuriko Nakaoku, Soshiro Ogata, Kiyotaka Nemoto, Chikage Kakuta, Eri Kiyoshige, Kanako Teramoto, Kiyomasa Nakatsuka, Gantsetseg Ganbaatar, Masafumi Ihara, Kunihiro Nishimura

“…Finally, MCI identification models were developed using a penalized logistic regression model with an elastic net algorithm.ResultsAmong the 148 participants (mean age, 78.6 ± 5.2 years), 44.6% were identified as having MCI. …”
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Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation. by Katherine I Morley, Joshua Wallace, Spiros C Denaxas, Ross J Hunter, Riyaz S Patel, Pablo Perel, Anoop D Shah, Adam D Timmis, Richard J Schilling, Harry Hemingway

“…<h4>Results</h4>The phenotype algorithm incorporated 286 codes: 201 Read, 63 BNF, 18 ICD-10, and four OPCS-4. …”
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Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech by Julianna Olah, Win Lee Edwin Wong, Atta-ul Raheem Rana Chaudhry, Omar Mena, Sunny X. Tang

“…Linguistic and paralinguistic features were extracted and ensemble learning algorithms (e.g., XGBoost) were used to train models. …”
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Predicting diabetic peripheral neuropathy through advanced plantar pressure analysis: a machine learning approach by Mehewish Musheer Sheikh, Mamatha Balachandra, Narendra V. G., Arun G. Maiya

“…An automated image processing algorithm segmented plantar pressure images into forefoot and hindfoot regions for precise pressure distribution measurement. …”
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An Automatic Measurement Method of Test Beam Response Based on Spliced Images by Dong Liang, Jing Liu, Lida Wang, Chenjing Liu, Jia Liu

“…Next, the spliced image is obtained through the PCA-SIFT method with a screening mechanism. The cracks’ information is acquired by the dual network model. …”
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Application of Data Mining Technology on Surveillance Report Data of HIV/AIDS High-Risk Group in Urumqi from 2009 to 2015 by Dandan Tang, Man Zhang, Jiabo Xu, Xueliang Zhang, Fang Yang, Huling Li, Li Feng, Kai Wang, Yujian Zheng

“…The goal of this study was to use four data mining algorithms to establish the identification model of HIV infection and compare their predictive performance. …”
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Optimization of the Canopy Three-Dimensional Reconstruction Method for Intercropped Soybeans and Early Yield Prediction by Xiuni Li, Menggen Chen, Shuyuan He, Xiangyao Xu, Panxia Shao, Yahan Su, Lingxiao He, Jia Qiao, Mei Xu, Yao Zhao, Wenyu Yang, Wouter H. Maes, Weiguo Liu

“…Point cloud preprocessing was refined through the application of secondary transformation matrices, color thresholding, statistical filtering, and scaling. Key algorithms—including the convex hull algorithm, voxel method, and 3D α-shape algorithm—were optimized using MATLAB, enabling the extraction of multi-dimensional canopy parameters. …”
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Cross-validation of the safe supplement screener (S3) predicting consistent third-party-tested nutritional supplement use in NCAA Division I athletes by Kinta D. Schott, Avaani Bhalla, Emma Armstrong, Ryan G. N. Seltzer, Floris C. Wardenaar

“…IntroductionThis cross-sectional study aimed to cross-validate an earlier developed algorithm-based screener and explore additional potential predictors for whether athletes will use third-party-tested (TPT) supplements.MethodsTo justify the initial model behind the supplement safety screener (S3) algorithm which predicts whether athletes will use TPT supplements, a cross-validation was performed using this independent dataset based on responses of a large group of collegiate NCAA DI athletes. …”
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Effectiveness of mindfulness-based therapy, stress reduction in hypertension and prehypertension: a systematic review by D. I. Nozdrachev, M. N. Solovieva, K. A. Zamyatin

“…The systematic review was prepared according to the PRISMA algorithm with minor modifications. The search algorithm included articles in Russian and English, indexed in the Pubmed/MEDLINE and Cochrane Library databases. …”
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