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Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation
Published 2025-03-01“…These discoveries were further validated in subsequent mouse models. An HFHC-induced NASH mouse model was used to validate the therapeutic effects and potential mechanisms of LQAtta on NASH.Results: From the UHPLC-MS/MS analysis of LQAtta, a total of 1518 chemical components were identified, with 106 of them being absorbed into the bloodstream. …”
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1222
Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis
Published 2025-06-01“…Finally, a DVT rat model was established to verify the expression of critical circRNAs and hub genes using real-time quantitative PCR.ResultsA total of 421 circRNAs and 1,082 mRNAs were differentially expressed in DVT. …”
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1223
The performance of artificial intelligence in image-based prediction of hematoma enlargement: a systematic review and meta-analysis
Published 2025-12-01“…Two reviewers independently screened the retrieved citations and extracted data. …”
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1224
人工智能融合临床与多组学数据在卒中防治及医药研发中的应用与挑战Applications and Challenges of Integrating Artificial Intelligence with Clinical and Multi-omics Data in Stroke Prevention, Treatment, and Pharmaceut...
Published 2025-06-01“…By integrating and analyzing clinical and multi-omics data, AI technology enhances the identification of high-risk populations, optimizes early diagnosis and risk assessment, enables precise subtyping of stroke, facilitates the screening of potential drug targets, and constructs prognostic prediction models. …”
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1225
Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
Published 2025-02-01“…We integrated the genes screened by three machine learning models (LASSO, SVM, and Random Forest), and CXCR4 was identified as a key gene with potential therapeutic value in DFUs. …”
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1226
Identification and mechanism analysis of biomarkers related to butyrate metabolism in COVID-19 patients
Published 2025-12-01“…Six machine learning algorithms were employed to determine the best model for identifying biomarkers, and receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic value of the biomarkers in COVID-19. …”
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1227
Use of artificial intelligence to support prehospital traumatic injury care: A scoping review
Published 2024-10-01“…Conclusions A small but growing body of literature described AI models based on prehospital features that may support decisions made by dispatchers, Emergency Medical Services clinicians, and trauma teams in early traumatic injury care.…”
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1228
Design, Fabrication, and Application of Large-Area Flexible Pressure and Strain Sensor Arrays: A Review
Published 2025-03-01“…The rapid development of flexible sensor technology has made flexible sensor arrays a key research area in various applications due to their exceptional flexibility, wearability, and large-area-sensing capabilities. …”
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1229
Exploring the predictive values of CRP and lymphocytes in coronary artery disease based on a machine learning and Mendelian randomization
Published 2024-09-01“…Techniques employed included propensity score matching (PSM), logistic regression, lasso regression, and random forest algorithms (RF). Risk factors were assessed, and the sensitivity and specificity of the models were evaluated using receiver operating characteristic (ROC) curves. …”
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1230
Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study
Published 2025-07-01“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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1231
Estimation of the water content of needles under stress by Erannis jacobsoni Djak. via Sentinel-2 satellite remote sensing
Published 2025-04-01“…Multiple vegetation indices are screened via recursive feature elimination cross validation (RFECV), and then support vector regression (SVR) and back-propagation neural network (BP) models are used to predict the leaf weight content fresh (LWCF) and leaf weight content dry (LWCD) of needles over a large area. …”
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1232
Locating and quantifying CH<sub>4</sub> sources within a wastewater treatment plant based on mobile measurements
Published 2025-04-01“…We utilized a multi-source Gaussian plume model combined with a genetic algorithm inversion framework, designed to locate major sources within the plant and quantify the corresponding <span class="inline-formula">CH<sub>4</sub></span> emission fluxes. …”
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1233
Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation
Published 2025-06-01“…Among the best-performing models with the least sensor data requirement, the ML algorithm predicted depressive symptoms with an accuracy of 80.6% (F1-score=0.76), high global MS symptom burden with an accuracy of 77.3% (F1-score=0.78), severe fatigue with an accuracy of 73.8% (F1-score=0.74), and poor sleep quality with an accuracy of 72.0% (F1-score=0.70). …”
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1234
Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques
Published 2025-03-01“…The utilization of the receiver operating characteristic curve in conjunction with the nomogram model served to authenticate the discriminatory strength and efficacy of the key genes. …”
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1235
Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases.
Published 2018-01-01Get full text
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1236
Epidemiology and Association Rules Analysis for Pulmonary Tuberculosis Cases with Extrapulmonary Tuberculosis from Age and Gender Perspective: A Large-Scale Retrospective Multicent...
Published 2023-01-01“…The multivariable logistic regression models demonstrated that odds ratios of concurrent PTB-EPTB cases varied by gender and age group. …”
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INTERNATIONAL FORUM “OLD AND NEW MEDIA: ALONG THE PATH TOWARDS A NEW AESTHETICS” / МЕЖДУНАРОДНЫЙ ФОРУМ «СТАРЫЕ И НОВЫЕ МЕДИА: ПУТИ К НОВОЙ ЭСТЕТИКЕ»...
Published 2019-06-01“…Along with the formulation of the enumerated questions, the presentations of the participants of the conference concretized the conclusions about the influence of new media on the cognitive capabilities of man, his means of action, “new plasticity” and a new way of living. Notice was made of alarming tendencies of transforming consciousness into that of “gamers,” reacting in correlations with certain algorithms, and a transference from discourse and substantiations towards reactions and evaluations. …”
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1238
Project quality, regulation quality
Published 2024-06-01“…These tools legitimise choices where conformity to the standard acts as a screen for the assumption of precise responsibilities. …”
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1239
Identification of biomarkers associated with inflammatory response in Parkinson's disease by bioinformatics and machine learning.
Published 2025-01-01“…LASSO, SVM-RFE and Random Forest algorithms were used to screen biomarker genes. Then, ROC curves were drawn and PD risk predicting models were constructed on the basis of the biomarker genes. …”
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Identifying potential three key targets gene for septic shock in children using bioinformatics and machine learning methods
Published 2025-06-01“…Three kinds of machine learning models were established, and the candidate genes were screened by intersection to obtain the core genes with diagnostic value. …”
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