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1081
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1082
Identification and analysis of neutrophil extracellular trap-related genes in periodontitis via bioinformatics and experimental verification
Published 2025-08-01“…Then, machine learning algorithms were exploited to screen hub NRGs, and a predictive model was constructed based on these hub NRGs. …”
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1083
Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target
Published 2025-08-01“…Using differential expression analysis and machine learning algorithms, 12 potential hub genes were successfully screened. …”
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1084
Prevalence and associated factors of mammography uptake among the women aged 45 years and above: policy implications from the longitudinal ageing study in India wave I survey
Published 2025-03-01“…A low proportion of Indian female population in reproductive age group (30–49 years) underwent breast cancer screening. The national operational framework includes mammography as one of the investigation modalities under the algorithm for early detection and management of breast cancer. …”
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1085
SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses
Published 2025-08-01“…A SUMOylation Risk Score (SRS) model was developed using 69 machine learning models across 10 algorithms, with performance evaluated by C-index and AUC. …”
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1086
High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs
Published 2025-05-01“…Background Despite the increasing use of non-invasive respiratory support in paediatric intensive care units, there are no large randomised controlled trials comparing two commonly used non-invasive respiratory support modes, continuous positive airway pressure and high-flow nasal cannula therapy. …”
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1087
The application of artificial intelligence in upper gastrointestinal cancers
Published 2025-04-01“…Finally, the current limitations and challenges faced in the field of upper gastrointestinal cancers were summarized, and explorations were conducted on the selection of AI algorithms in various scenarios, the popularization of early screening, the clinical applications of AI, and large multimodal models.…”
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1088
PRKDC regulates cGAMP to enhance immune response in lung cancer treatment
Published 2024-11-01“…This study aimed to investigate the antitumor effects of 2’,3’-cGAMP in LUAD.MethodHerein, patients with LUAD were screened for prognostic biomarkers, which were then assessed for sensitivity to immunotherapy and chemotherapy utilizing the “TIDE” algorithm and CellMiner database. …”
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1089
Maximizing YOLOv2 efficiency: A study on multiclass detection of indoor objects
Published 2025-06-01“…The objective of the present study is to present a systematic approach for optimizing the key hyperparameters of YOLOv2 model for multiclass object detection, specifically targeting seven classes of indoor objects: chair, fire extinguisher, printer, screen, trash bin, exit, and clock. …”
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1090
Association between the development of sepsis and the triglyceride-glucose index in acute pancreatitis patients: a retrospective investigation utilizing the MIMIC-IV database
Published 2025-02-01“…Utilizing the formula ln[(triglycerides mg/dl) × (glucose mg/dl)/2], the TyG index was calculated. The Boruta algorithm and Xgboost model were used for feature selection in order to pinpoint the important variables affecting results. …”
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1091
Personalized prediction of negative affect in individuals with serious mental illness followed using long-term multimodal mobile phenotyping
Published 2025-05-01“…A range of statistical approaches, including a novel personalized ensemble machine learning algorithm, were compared in their ability to predict states of heightened negative affect. …”
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1092
Research on the Evaluation of the Node Cities of China Railway Express Based on Machine Learning
Published 2025-06-01“…The Random Forest model outperformed comparative algorithms with 99.5% prediction accuracy (8.33% higher than conventional classification models), particularly in handling multi-dimensional interactions between urban development factors. …”
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1093
Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes.
Published 2024-01-01“…According to the five machine algorithms, 4 features (S100A2, GNGT1, NEUROD4, FCN2) were screened and used to create a PD diagnostic model. …”
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1094
Unveiling the ageing-related genes in diagnosing osteoarthritis with metabolic syndrome by integrated bioinformatics analysis and machine learning
Published 2025-12-01“…The limma package was used to identify differentially expressed genes (DEGs), and weighted gene coexpression network analysis (WGCNA) screened gene modules, and machine learning algorithms, such as random forest (RF), support vector machine (SVM), generalised linear model (GLM), and extreme gradient boosting (XGB), were employed. …”
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1095
Biophysical and nutritional combination treatment for myosteatosis in patients with sarcopenia: a study protocol for single-blinded randomised controlled trial
Published 2024-01-01“…The findings of this study will demonstrate the effect of combination treatment as an alternative for managing sarcopenia.Methods and analysis In this single-blinded randomised controlled trial, subjects will be screened based on the Asian Working Group for Sarcopenia (AWGS) 2019 definition. 200 subjects who are aged 65 or above and identified sarcopenic according to the AWGS algorithm will be recruited. …”
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1096
Kun–Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile
Published 2025-08-01“…We aim to develop multimodal risk prediction models by integrating genomics and artificial intelligence algorithms. …”
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1097
Identification of hub genes for the diagnosis associated with heart failure using multiple cell death patterns
Published 2025-08-01“…Bioinformatics and machine learning algorithms were utilized to screen the HF key genes and PCD‐related HF hub genes, and an HF diagnostic model was constructed on this. …”
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1098
New insights into biomarkers and risk stratification to predict hepatocellular cancer
Published 2025-04-01“…Through human studies compiled with animal models and mechanistic insight in pathways such as the TGF-β pathway, the biological progression from chronic liver disease to cirrhosis and HCC can be delineated. …”
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1099
ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer
Published 2025-01-01“…Utilizing three distinct machine learning algorithms, we identified three signature genes-PBX1, IGHM, and CXCL13-that exhibited significant diagnostic value within the diagnostic model. …”
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1100
Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study
Published 2025-08-01“…A machine learning study developed a parallel Convolutional Neural Network algorithm with 96.4% recall and 99.1% precision for study screening. …”
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