Gait-Based Parkinson’s Disease Detection Using Recurrent Neural Networks for Wearable Systems by Carlos Rangel-Cascajosa, Francisco Luna-Perejón, Saturnino Vicente-Diaz, Manuel Domínguez-Morales

“…The ability of Deep Learning algorithms to identify complex features from clinical data has proven to be a promising approach in various medical domains as support tools. …”
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A reproducible approach for the use of aptamer libraries for the identification of Aptamarkers for brain amyloid deposition based on plasma analysis. by Cathal Meehan, Soizic Lecocq, Gregory Penner

“…Eight aptamers were identified as a result of the selection process and screened across 390 plasma samples by qPCR assay. Results were analysed using multiple machine learning algorithms from the Scikit-learn package along with clinical variables including cognitive status, age and sex to create predictive models. …”
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Critical review of OCT in clinical practice for the assessment of oral lesions by Fariba Esperouz, Domenico Ciavarella, Mauro Lorusso, Andrea Santarelli, Lorenzo Lo Muzio, Giuseppina Campisi, Lucio Lo Russo

“…This is further complicated by the introduction and increased trend to adopt artificial intelligence (AI) algorithms in imaging evaluation. Machine learning and deep learning algorithms have shown superior diagnostic sensitivity and accuracy compared to clinician judgment. …”
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Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective stu... by Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen

“…Internal validation employed ROC analysis and calibration curves, while Shapley Additive Explanations (SHAP) values interpreted feature importance in the optimal model.ResultsAmong 2,921 screened patients, 1,272 met inclusion criteria. …”
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Identifying Data-Driven Clinical Subgroups for Cervical Cancer Prevention With Machine Learning: Population-Based, External, and Diagnostic Validation Study by Zhen Lu, Binhua Dong, Hongning Cai, Tian Tian, Junfeng Wang, Leiwen Fu, Bingyi Wang, Weijie Zhang, Shaomei Lin, Xunyuan Tuo, Juntao Wang, Tianjie Yang, Xinxin Huang, Zheng Zheng, Huifeng Xue, Shuxia Xu, Siyang Liu, Pengming Sun, Huachun Zou

“…We trained a supervised machine learning model and developed pathways to classify individuals before evaluating its diagnostic validity and usability on an external cohort. …”
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Bioinformatics analysis of ferroptosis-related biomarkers and potential drug predictions in doxorubicin-induced cardiotoxicity by Jian Yu, Jian Yu, Jiangtao Wang, Xinya Liu, Xinya Liu, Cancan Wang, Cancan Wang, Li Wu, Yuanming Zhang, Yuanming Zhang

“…Utilized LASSO regression, SVM-RFE, and RF algorithms to identify key genes, followed by validation using external datasets (GSE232331, GSE230638) and ROC curve plotting to determine the diagnostic value of key genes. …”
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Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…A series of machine learning algorithms was used to screen two feature genes (ETS1 and IL7R) to establish the diagnostic model, which exhibited satisfactory diagnostic efficiency. …”
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Association between age and lung cancer risk: evidence from lung lobar radiomics by Yuwei Li, Chengting Lin, Lei Cui, Chao Huang, Liting Shi, Shiyang Huang, Yue Yu, Xianglan Zhou, Qian Zhou, Kun Chen, Lei Shi

“…The minimum redundancy maximum relevance algorithm was applied to identify the top 10 age-related radiomic features among 13,137 never smokers. …”
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Bidirectional Relationship Between Hypoalbuminemia and Postoperative Pneumonia in Elderly Hip Fracture Patients: A Retrospective Cohort Study by Wang J, Yu H, Xu X, Guo J

“…After predefined participants selection inclusion and exclusion criteria, 1661 surgically treated HF patients were included and analyzed utilizing multiple statistical models, including univariate logistic regression, Lasso regression, and Boruta algorithm for variable selection, while multivariate logistic regression and propensity score matching (PSM) for assess the bidirectional relationship between hypoalbuminemia and postoperative pneumonia. …”
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Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome by Ge Jin, Xiaomei Fan, Xiaoliang Liang, Honghong Dai, Jun Wang

“…The risk score model constructed based on these biomarkers could effectively predict the survival rate of cervical cancer patients (AUC >0.6 for 1/3/5 years). …”
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Registered report protocol: A scoping review to identify potential predictors as features for developing automated estimation of the probability of being frail in secondary care. by Dirk H van Dalen, Angèle P M Kerckhoffs, Esther de Vries

“…We aim to identify potential predictors that could be used as features for modeling algorithms on the basis of routine hospital EHR data to incorporate in an automated tool for estimating the probability of being frail.…”
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Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway by Lemei Hu, Changqing Zheng, Ying Kong, Zhiqing Luo, Fengzhang Huang, Zhigang Zhu, Quhuan Li, Ming Liang

“…By constructing an in vitro CTSG overexpression model in VSMCs, we found that CTSG upregulated the expression of MMP2 and MMP9 while downregulating the expression of collagen I and collagen III. …”
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Machine learning approach effectively discriminates between Parkinson’s disease and progressive supranuclear palsy: Multi-level indices of rs-fMRI by Weiling Cheng, Xiao Liang, Wei Zeng, Jiali Guo, Zhibiao Yin, Jiankun Dai, Daojun Hong, Fuqing Zhou, Fangjun Li, Xin Fang

“…Various rs-fMRI indices were extracted, followed by a comprehensive feature screening for each index. We constructed fifteen distinct combinations of indices and selected four machine learning algorithms for model development. …”
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EDITORIAL: ARTIFICIAL INTELLIGENCE AND ITS TRANSFORMATIVE IMPACT ON SCIENTIFIC PUBLISHING by Abubakar Munir

“…The most significant impact that AI has made on publishing is speeding up the peer review process. …”
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Lesion classification and diabetic retinopathy grading by integrating softmax and pooling operators into vision transformer by Chong Liu, Weiguang Wang, Jian Lian, Wanzhen Jiao

“…Therefore, plenty of automated screening technique have been developed to address this task.MethodsAmong these techniques, the deep learning models have demonstrated promising outcomes in various types of machine vision tasks. …”
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Development and validation of a nomogram for predicting in-hospital mortality in older adult hip fracture patients with atrial fibrillation: a retrospective study by Zhenli Li, Jing He, Tiezhu Yao, Guang Liu, Jing Liu, Ling Guo, Mengjia Li, Mengjia Li, Zhengkun Guan, Zhengkun Guan, Ruolian Gao, Jingtao Ma

“…Logistic regression (LR) and Least Absolute Shrinkage and Selection Operator (LASSO) algorithms were employed to screen features. We further used Extreme Gradient Boosting (XGBoost) based on features selected by LR and LASSO algorithms to assist in identifying the final model-established features. …”
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Single-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma by Yan Liao, Junkai Chen, Hao Yao, Ting Zheng, Jian Tu, Weidong Chen, ZeHao Guo, Yutong Zou, Lili Wen, Xianbiao Xie

“…Multiple analytical algorithms indicated that SLCs were associated with immune cell infiltration and immune checkpoint gene expression. …”
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Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis by Ma J, Li W, Ma Q, Ding L, Wang Z, Wang R, Huang Y, Ma G, Gao J

“…Jie Ma,1,2,* Wendi Li,3 Qianqian Ma,1 Liying Ding,4 Zhaoyun Wang,1 Rong Wang,1 Yanan Huang,1 Gang Ma,2,* Jun Gao1,* 1Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China; 3Department of Child Rehabilitation Education, Ningxia Rehabilitation Center for the Disabled, Yinchuan, Ningxia, 750002, People’s Republic of China; 4Department of Gynecology, Gynecology Clinic of Li Ying, Wuzhong, Ningxia, 751100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gang Ma, Department of Anesthesia and Perioperative Medicine, General Hospital of Ningxia Medical University, The First Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750004, People’s Republic of China, Email magang2671@163.com Jun Gao, Department of Anesthesia and Perioperative Medicine, First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University, Yinchuan, Ningxia, 750001, People’s Republic of China, Email gaojun1605@sina.comIntroduction: This study aimed to identify diagnostic and therapeutic biomarkers related to glucose metabolism in sepsis, as hyperglycemia and blood glucose fluctuations influence sepsis progression.Methods: Datasets from public databases were analyzed using various methods, including differential expression analysis, PPI network screening, machine learning algorithms and Mendelian randomization. …”
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Long-term risk of de novo malignancy with tumor necrosis factor alpha (TNF) inhibitor immunosuppression: a multicenter, retrospective cohort study by Conor B. Driscoll, Jordan M. Rich, Christopher Yang, Joseph Nicolas, Dylan Isaacson, Philip Silberman, Xinlei Mi, Sai Kaushik Shakar Ramesh Kumar, Hui Zhang, Steven Belknap, William H. Temps, Edward M. Schaeffer, Shilajit D. Kundu

“…There may need to be differential cancer screening algorithms for patients with different inflammatory conditions and TNF-I exposure.…”
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Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1 by Tingting Liu, Tingting Pan, Mingxin Chang, Shaojie Fu, Hongzhao Xu, Hao Wu, Zhonggao Xu, Yanli Cheng

“…Among them, dual specificity phosphatase 1 (DUSP1) was screened as FFG by three machine learning algorithms. …”
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