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Cystic Fibrosis Newborn Screening: A Systematic Review-Driven Consensus Guideline from the United States Cystic Fibrosis Foundation
Published 2025-04-01“…Systematic reviews were used to develop seven recommendations for newborn screening program practices to improve timeliness, sensitivity, and equity in diagnosing infants with CF: (1) The CF Foundation recommends the use of a floating immunoreactive trypsinogen (IRT) cutoff over a fixed IRT cutoff; (2) The CF Foundation recommends using a very high IRT referral strategy in CF newborn screening programs whose variant panel does not include all CF-causing variants in CFTR2 or does not have a variant panel that achieves at least 95% sensitivity in all ancestral groups within the state; (3) The CF Foundation recommends that CF newborn screening algorithms should not limit <i>CFTR</i> variant detection to the F508del variant or variants included in the American College of Medical Genetics-23 panel; (4) The CF Foundation recommends that CF newborn screening programs screen for all CF-causing <i>CFTR</i> variants in CFTR2; (5) The CF Foundation recommends conducting <i>CFTR</i> variant screening twice weekly or more frequently as resources allow; (6) The CF Foundation recommends the inclusion of a <i>CFTR</i> sequencing tier following IRT and <i>CFTR</i> variant panel testing to improve the specificity and positive predictive value of CF newborn screening; (7) The CF Foundation recommends that both the primary care provider and the CF specialist be notified of abnormal newborn screening results. …”
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122
Ensemble Algorithm Based on Gene Selection, Data Augmentation, and Boosting Approaches for Ovarian Cancer Classification
Published 2024-12-01“…<b>Results:</b> The target genes were screened and combined with data augmentation and ensemble boosting algorithms. …”
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123
Developing an Algorithm for Detecting Suspicious Trades in Tehran Stock Exchange Based on Spoof Trading Model
Published 2023-03-01“…More specifically, this paper studies manipulated stocks by looking at market microstructure (intraday transactions) and aims to introduce an algorithm for detecting suspicious trades so that regulators can detect them beforehand. …”
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124
Improved adaptive FPGA dark channel prior dehazing algorithm for edge applications in agricultural scenarios
Published 2025-12-01“…Through field data acquisition and a self-developed adaptive mechanism, the system achieves adaptive processing across varying fog densities while mitigating the screen flickering inherent to adaptive systems. Based on the sky brightness distribution, a more effective sky-region segmentation strategy was designed to address overexposure in the sky region of dehazed images. …”
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125
Aggregation of cardiovascular risk factors in a cohort of 40-year-olds participating in a population-based health screening program in Sweden
Published 2024-11-01“…SCORE2 was calculated according to the algorithm provided by the SCORE2 working group and ESC (European Society of Cardiology) Cardiovascular Risk Collaboration. …”
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Multimodal Approach (MRI and Ultrasonography) to the Diagnosis of Fetal Congenital Heart Diseases
Published 2024-11-01“…In 85.7% of the fetuses, the findings of different imaging techniques fully coincided with the autopsy findings.Conclusions: In this cohort of pregnant women, the second screening should include more examinations to verify the diagnosis of CHD. …”
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128
MFPSP: Identification of fungal species-specific phosphorylation site using offspring competition-based genetic algorithm.
Published 2024-11-01“…The comparison results shown that MFPSP achieves a more advanced and balanced performance to several state-of-the-art available toolkits. …”
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129
Identification and Validation of NK Marker Genes in Ovarian Cancer by scRNA-seq Combined with WGCNA Algorithm
Published 2023-01-01“…The WGCNA algorithm screens NK cell marker genes based on bulk RNA transcriptome patterns. …”
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130
A Radio Frequency Interference Screening Framework—From Quick-Look Detection Using Statistics-Assisted Network to Raw Echo Tracing
Published 2024-11-01“…We take the data of Sentinel-1 terrain observation with progressive scan (TOPS) mode as an example. By combining the statistics-assisted network with the sliding-window algorithm and the error-tolerant training strategy, it is possible to accurately detect and locate RFI in the quick looks of an SLC product. …”
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131
Precision Measurement and Feature Selection in Medical Diagnostics using Hybrid Genetic Algorithm and Support Vector Machine
Published 2025-07-01“…This study contributes to the development of more accurate and efficient breast cancer screening tools to help healthcare providers make informed diagnostic decisions.…”
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Data transmission algorithm for mobile wireless sensor network based on power loss equalization control mechanism
Published 2018-11-01“…In order to solve the problem of synchronization addressing and the inadequacy of power interaction among nodes in the current mobile wireless sensor network,a new data transmission algorithm for mobile wireless sensor network was proposed.Firstly,the broadcast mechanism was adopted to realize synchronous control packet transmission and reduce the pressure caused by the synchronization flow to the addressing process.Then regional node flow valve control mechanism was used,and data traffic between sink nodes and regional node links were recorded and got by interception,flow link equalization was further adopted to promote traffic equalization.in the further step.Finally,the limited bandwidth based on wheel number-sink link jitter screening mode could be identified,and the transmission failure due to limited bandwidth was reduced.Simulation results show that compared with the bandwidth of the root zone node and widely used in limiting transmission algorithm,node link stability encoding algorithm and hierarchical encoding algorithm,the data transmission bandwidth can be improved,the packet loss rate can be reduced,and the practical needs can be better met.…”
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134
An Integrated Fault Diagnosis Method for Rotating Machinery Based on Improved Multivariate Multiscale Amplitude-Aware Permutation Entropy and Uniform Phase Empirical Mode Decomposi...
Published 2021-01-01“…This algorithm is combined with the Uniform Phase Empirical Mode Decomposition (UPEMD) method and the t-distributed Stochastic Neighbor Embedding (t-SNE) method, forming a new time-frequency multiscale feature extraction method. …”
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135
A recurrent neural network and parallel hidden Markov model algorithm to segment and detect heart murmurs in phonocardiograms.
Published 2024-11-01“…These properties make the algorithm a promising tool for screening of abnormal heart murmurs.…”
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136
Development and Internal Validation of a Machine Learning-Based Colorectal Cancer Risk Prediction Model
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137
SARS-CoV-2 Prediction Strategy Based on Classification Algorithms from a Full Blood Examination
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138
Predicting Early-Onset Colorectal Cancer in Individuals Below Screening Age Using Machine Learning and Real-World Data: Case Control Study
Published 2025-06-01“…Accurate early prediction and a thorough understanding of the risk factors for early-onset colorectal cancer (EOCRC) are vital for effective prevention and treatment, particularly for patients below the recommended screening age. ObjectiveOur study aims to predict EOCRC using machine learning (ML) and structured electronic health record data for individuals under the screening age of 45 years, with the aim of exploring potential risk and protective factors that could support early diagnosis. …”
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139
Feature Selection based on Genetic Algorithm for Classification of Mammogram Using K-means, k-NN and Euclidean Distance
Published 2023-02-01“…., the classifications was done on the bases of the features selected using genetic algorithm. Attempts have also been made to study the performance of each feature selected by Genetic Algorithm (GA) in classification. …”
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Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell
Published 2024-05-01“…Experimental studies of tumor cell cultures were carried out using the MTT testwith aquacobalamin and HECСA on cell lines of immortalized (telomerized) fibroblasts (Fb-hTERT), lung carcinoma (A549), and breast duct cancer (BT-474).Results. Chemoreactome screening of the effects of molecules on tumor cells made it possible to obtain estimates of cell growth IC50 for 470 tumor cell lines. …”
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