A computer-driven ventilator liberation protocol in pediatric patients: a single-center pilot randomized controlled trial by Song Chen, Changxue Xiao, Xue Lu, Min Liao, Chengjun Liu, Feng Xu, Jing Li

“…The test group underwent ventilator liberation driven by a computerized algorithm combining protocolized screening, air leak testing, and spontaneous breathing testing. …”
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Analysis of risk factors of acute respiratory failure after radical resection of esophageal cancer by two methods by LEI Xiuwen, ZHU Xiaolei, TIAN Long

“…The combination of the two methods is conducive to the joint screening of risk factors for ARF after radical resection for esophageal cancer, and the three rules are more valuable in guiding clinical intervention." …”
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Cell death-related signature genes: risk-predictive biomarkers and potential therapeutic targets in severe sepsis by Yanan Li, Yuqiu Tan, Zengwen Ma, Zengwen Ma, Weiwei Qian, Weiwei Qian

“…Further combining cell death-related gene screening and four machine learning algorithms (including LASSO-logistic, Gradient Boosting Machine, Random Forest and xGBoost), nine SeALAR-characterized cell death genes (SeDGs) were screened and a risk prediction model based on SeDGs was constructed that demonstrated good prediction performance. …”
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Opening closed doors: using machine learning to explore factors associated with marital sexual violence in a cross-sectional study from India by Anita Raj, Abhishek Singh, Nandita Bhan, Lotus McDougal, Nabamallika Dehingia, Julian McAuley

“…Analyses included iterative thematic analysis (L-1 regularised regression followed by iterative qualitative thematic coding of L-2 regularised regression results) and neural network modelling.Outcome measure Participants reported their experiences of sexual violence perpetrated by their current (or most recent) husband in the previous 12 months. …”
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Improving the accuracy of remotely sensed TSS and turbidity using quality enhanced water reflectance by a statistical resampling technique by Kunwar Abhishek Singh, Dongryeol Ryu, Meenakshi Arora, Manoj Kumar Tiwari, Bhabagrahi Sahoo

“…The statistical resampling approach based on GMM was applied to Sentinel-2 (S2) imagery to produce input to Machine Learning (ML) algorithms to retrieve the TSS and turbidity for target river sections. …”
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Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review by Martins Nweke, Nombeko Mshunqane

“…Predictive and preventative models should target factors with a high causality index and low investigative costs. …”
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Exploring pesticide risk in autism via integrative machine learning and network toxicology by Ling Qi, Jingran Yang, Qiao Niu, Jianan Li

“…Each combination of 1–23 targets was used to construct predictive models using eight different machine learning algorithms. …”
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Machine learning-derived prognostic signature integrating programmed cell death and mitochondrial function in renal clear cell carcinoma: identification of PIF1 as a novel target by Guangyang Cheng, Zhaokai Zhou, Shiqi Li, Fu Peng, Shuai Yang, Chuanchuan Ren

“…Finally, a novel RCC prognostic marker PIF1 was identified in model genes. The knockdown of PIF1 in vitro inhibited the progression of renal carcinoma cells. …”
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Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, a... by Guoqing Liu, Xiangwen Lv, Jiahui Qin, Xingqing Long, Miaomiao Zhu, Chuwen Fu, Jian Xie, Peichun He

“…Hub genes were screened using the least absolute shrinkage and selection operator (LASSO) and random forest (RF) algorithms. …”
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Development and validation of a nomogram for predicting in-hospital mortality in older adult hip fracture patients with atrial fibrillation: a retrospective study by Zhenli Li, Jing He, Tiezhu Yao, Guang Liu, Jing Liu, Ling Guo, Mengjia Li, Mengjia Li, Zhengkun Guan, Zhengkun Guan, Ruolian Gao, Jingtao Ma

“…Logistic regression (LR) and Least Absolute Shrinkage and Selection Operator (LASSO) algorithms were employed to screen features. We further used Extreme Gradient Boosting (XGBoost) based on features selected by LR and LASSO algorithms to assist in identifying the final model-established features. …”
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Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma by Can Xu, Jin Yang, Huan Xiong, Xiaoteng Cui, Yuhao Zhang, Mingjun Gao, Lei He, Qiuyue Fang, Changxi Han, Wei Liu, Yangyang Wang, Jin Zhang, Ying Yuan, Zhaomu Zeng, Ruxiang Xu

“…The Lasso, Cox, and Step machine learning algorithms were used to construct and screen the optimal risk assessment prognostic model. …”
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Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis by Qiang Shen, Lin Fan, Chen Jiang, Dingyi Yao, Xingyu Qian, Fuqiang Tong, Zhengfeng Fan, Zongtao Liu, Nianguo Dong, Chao Zhang, Jiawei Shi

“…Machine learning (ML) algorithms were employed to screen potential biomarkers. …”
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Signatures of Six Autophagy‐Related Genes as Diagnostic Markers of Thyroid‐Associated Ophthalmopathy and Their Correlation With Immune Infiltration by Qintao Ma, Yuanping Hai, Jie Shen

“…The combined six‐gene model also showed good diagnostic efficacy (AUC = 0.948). …”
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Identifying and Validating an Acidosis-Related Signature Associated with Prognosis and Tumor Immune Infiltration Characteristics in Pancreatic Carcinoma by Pingfei Tang, Weiming Qu, Dajun Wu, Shihua Chen, Minji Liu, Weishun Chen, Qiongjia Ai, Haijuan Tang, Hongbing Zhou

“…Univariate Cox regression and the Kaplan–Meier method were applied to screen for prognostic genes. The least absolute shrinkage and selection operator (LASSO) Cox regression was used to establish the optimal model. …”
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Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics by Haiting Ye, Xiang Zhang, Pengyan Li, Mei Wang, Ruolan Liu, Dingping Yang

“…Immune cell infiltration was analyzed using the CIBERSORT algorithm, and potential associations between the hub genes and clinicopathological features were explored based on the Nephroseq database. …”
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Identification and analysis of neutrophil extracellular trap-related genes in periodontitis via bioinformatics and experimental verification by Miao Yu, Zhenqi Ye, Zixin Ye, Yaping Wu, Xiang Wu

“…Then, machine learning algorithms were exploited to screen hub NRGs, and a predictive model was constructed based on these hub NRGs. …”
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SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses by Kaiping Luo, Kaiping Luo, Donghui Xing, Donghui Xing, Xiang He, Yixin Zhai, Yanan Jiang, Hongjie Zhan, Zhigang Zhao

“…A SUMOylation Risk Score (SRS) model was developed using 69 machine learning models across 10 algorithms, with performance evaluated by C-index and AUC. …”
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Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy by Zachary F. Greenberg, Samantha Ali, Andrew Brock, Jinmai Jiang, Thomas D. Schmittgen, Song Han, Steven J. Hughes, Kiley S. Graim, Mei He

“…Through modelling the ATP6V0B cycling threshold, we reported 3 models with AUCs between 0.86 and 0.88, showcasing an enabling and clinically translatable liquid biopsy approach for early detection of pancreatic cancer using circulating EVs. …”
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Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis by Chengze Qiu, Zhiyong Zhang, Haocheng Wang, Na Liu, Ruixin Li, Zhiheng Wei, Benjie Wang, Nan Zhang

“…An artificial neural network model was constructed for the hub genes, and immune analysis was conducted using the ssGSEA algorithm. …”
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Improving synergistic drug combination prediction with signature-based gene expression features in oncology by Mozhgan Mozaffarilegha, Sajjad Gharaghani

“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
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