Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis by Ji Hui Fan, Xiao Min Li

“…Furthermore, three hub mRNAs (BOC, MLST8, and HMGCS2) from the CeRNA network were screened using LASSO algorithms. GSEA analysis revealed that hub mRNAs were implicated in a great deal of immune system responses and inflammatory pathways, including IL-5 production, MAPK signaling pathway, and JAK-STAT signaling pathway. …”
Get full text

Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation by Yuchen Cai, Tianyi Zhou, Xueyao Cai, Wenjun Shi, Hao Sun, Yao Fu

“…Hub genes were further screened and validated by multiple machine learning (ML) algorithms, followed by a comprehensive visualization of single-cell atlas and immune landscape. …”
Get full text

DETERMINATION OF THE BASIC PARAMETERS OF SENSOR DEVICES FOR THE IMPLEMENTATION OF PSYCHONEUROLOGICAL RESEARCH WITH THE INTRODUCTION OF MULTITOUCH TECHNOLOGY by Karina Selivanova, Oleg Avrunin, Nikita Kazimirov

“…The scientific novelty and practical significance of the obtained results is the development of specialized software and algorithmic software for dynamic testing on sensory devices with the ability to video record the movements of the upper extremities in the mode "Rapid". …”
Get full text

Artificial intelligence applications in pediatric ophthalmology: A comprehensive review by Anupama Janardhanan, Meenakshi Ravindran, Allapitchai Fathima, Neelam Pawar

“…Furthermore, it explores existing AI models and their applicability in diagnosing refractive errors and strabismus. …”
Get full text

EDUCATIONAL TRAINING SIMULATOR FOR MONITORING READING TECHNIQUE AND SPEED BASED ON SPEECH-TO-TEXT (STT) METHODS by Olesia Barkovska, Heorhii Ivashchenko, Dmytro Rosinskiy, Daniil Zakharov

“…The results of testing children with dyslalia, meaning the rearrangement of sounds in words when reading, also showed that the Jaro algorithm has a shorter line comparison time for large text arrays (by 7%). …”
Get full text

Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation by Li S, Zhu H, Zhai Q, Hou Y, Yang Y, Lan H, Jiang M, Xuan J

“…These discoveries were further validated in subsequent mouse models. An HFHC-induced NASH mouse model was used to validate the therapeutic effects and potential mechanisms of LQAtta on NASH.Results: From the UHPLC-MS/MS analysis of LQAtta, a total of 1518 chemical components were identified, with 106 of them being absorbed into the bloodstream. …”
Get full text

Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis by Weiwei Chen, Ying Zhu, Sihua Niu, Yan Zhou, Jian Chang, Shujie Gan

“…Finally, a DVT rat model was established to verify the expression of critical circRNAs and hub genes using real-time quantitative PCR.ResultsA total of 421 circRNAs and 1,082 mRNAs were differentially expressed in DVT. …”
Get full text

The performance of artificial intelligence in image-based prediction of hematoma enlargement: a systematic review and meta-analysis by Wenjing Fan, Zhiping Wu, Wangyang Zhao, Luzhu Jia, Shuze Li, Wei Wei, Xin Chen

“…Two reviewers independently screened the retrieved citations and extracted data. …”
Get full text

Is body mass index associated with outcomes of mechanically ventilated adult patients in intensive critical units? A systematic review and meta-analysis. by Yonghua Zhao, Zhiqiang Li, Tao Yang, Meiping Wang, Xiuming Xi

Get full text

Progress on the application of supercomputer brain simulation technology by SUN Zhe

“…This review examines the theoretical principles and technical foundations of supercomputer brain simulation, including distributed parallel algorithms, graphics processing unit (GPU)⁃based acceleration, and multimodal data management. …”
Get full text

Gaussian Process Regression and Machine Learning Methods for Carbon-Based Material Adsorption by Manar Ahmed Hamza, Maha M. Althobaiti, Fahd N. Al-Wesabi, Rana Alabdan, Hany Mahgoub, Anwer Mustafa Hilal, Abdelwahed Motwakel, Mesfer Al Duhayyim

“…., warmth, solution pH) and adsorbent varieties, the created Ml algorithms outperformed classic isotherm models in conditions of generalisation. …”
Get full text

A beginner’s approach to deep learning applied to VS and MD techniques by Stijn D’Hondt, José Oramas, Hans De Winter

“…Abstract It has become impossible to imagine the fields of biochemistry and medicinal chemistry without computational chemistry and molecular modelling techniques. In many steps of the drug development process in silico methods have become indispensable. …”
Get full text

Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association with risk of de... by Giuseppe Barisano, Michael Iv, Jeiran Choupan, Melanie Hayden-Gephart, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Michael Donohue, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles DeCarli, Bret Borowski, Jeff Gunter, Matt Senjem, Prashanthi Vemuri, David Jones, Kejal Kantarci, Chad Ward, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chet Mathis, Susan Landau, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Virginia Lee, Magdalena Korecka, Michal Figurski, Karen Crawford, Scott Neu, Tatiana M. Foroud, Steven Potkin, Li Shen, Faber Kelley, Sungeun Kim, Kwangsik Nho, Zaven Kachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph Quinn, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Judith L. Heidebrink, Joanne L. Lord, Ronald Petersen, Sara S. Mason, Colleen S. Albers, David Knopman, Kris Johnson, Rachelle S. Doody, Javier Villanueva Meyer, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, Beau Ances, John C. Morris, Maria Carroll, Sue Leon, Erin Householder, Mark A. Mintun, Stacy Schneider, Angela Oliver, Daniel Marson, Randall Griffith, David Clark, David Geld-macher, John Brockington, Erik Roberson, Hillel Grossman, Effie Mitsis, Leyla deToledo-Morrell, Raj C. Shah, Ranjan Duara, Daniel Varon, Maria T. Greig, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Daniel D’Agostino, Stephanie Kielb, James E. Galvin, Dana M. Pogorelec, Brittany Cerbone, Christina A. Michel, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, Terence Z. Wong, Steven E. Arnold, Jason H. Karlawish, David Wolk, Charles D. Smith, Greg Jicha, Peter Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad, Oscar L. Lopez, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc Adams Ortiz, Kyle Womack, Dana Mathews, Mary Quiceno, Ramon Diaz Arrastia, Richard King, Myron Weiner, Kristen Martin Cook, Michael DeVous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S. Anderson, Russell H. Swerdlow, Liana Apostolova, Kathleen Tingus, Ellen Woo, Daniel H.S. Silverman, Po H. Lu, George Bartzokis, Neill R. Graff Radford, Francine Parfitt, Tracy Kendall, Heather Johnson, Martin R. Farlow, AnnMarie Hake, Brandy R. Matthews, Scott Herring, Cynthia Hunt, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra Black, Bojana Stefanovic, Curtis Caldwell, Ging-Yuek Robin Hsiung, Howard Feldman, Benita Mudge, Michele Assaly, Andrew Kertesz, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek Marsel Mesulam, Kristine Lipowski, Chuang Kuo Wu, Nancy Johnson, Carl Sadowsky, Walter Martinez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Jerome Yesavage, Joy L. Taylor, Barton Lane, Allyson Rosen, Jared Tinklenberg, Marwan N. Sabbagh, Christine M. Belden, Sandra A. Jacobson, Sherye A. Sirrel, Neil Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Joanne Allard, Alan Lerner, Paula Ogrocki, Leon Hudson, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T.Y. Lee, Rob Bartha, Sterling Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven G. Potkin, Adrian Preda, Dana Nguyen, Pierre Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Douglas W. Scharre, Maria Kataki, Anahita Adeli, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Robert B. Santulli, Tamar J. Kitzmiller, Eben S. Schwartz, Kaycee M. Sink, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Kenneth Spicer, David Bachman, Elizabeth Finger, Stephen Pasternak, Irina Rachinsky, John Rogers, Andrew Kertesz, Dick Drost, Nunzio Pomara, Raymundo Hernando, Antero Sarrael, Susan K. Schultz, Laura L. Boles Ponto, Hyungsub Shim, Karen Elizabeth Smith, Norman Relkin, Gloria Chaing, Lisa Raudin, Amanda Smith, Kristin Fargher, Balebail Ashok Raj

“…Methods: We developed a robust algorithm to automatically assess PVS count and size on clinical MRI, and investigated 1) their relationship with dementia risk and brain atrophy in participants without dementia, 2) their longitudinal evolution, and 3) their potential use as a screening tool in simulated clinical trials. …”
Get full text

Integrated single-cell and transcriptome sequencing data reveal the value of IL1RAP in gastric cancer microenvironment and prognosis by Weifeng Yang, Xiaohua Wu, Jian Wang, Wenquan Ou, Xing Huang

“…Three machine learning algorithms identified distinct sets of prognostic genes in gastric cancer patients. …”
Get full text

Integrating health equity in artificial intelligence for public health in Canada: a rapid narrative review by Samantha Ghanem, Marielle Moraleja, Danielle Gravesande, Jennifer Rooney

“…Several health equity considerations for applying AI in public health were identified, including gaps in AI epistemology, algorithmic bias, accessibility of AI technologies, ethical and privacy concerns, unrepresentative training datasets, lack of transparency and interpretability of AI models, and challenges in scaling technical skills.ConclusionWhile AI has the potential to advance public health in Canada, addressing equity is critical to preventing inequities. …”
Get full text

A Comprehensive Approach to Rustc Optimization Vulnerability Detection in Industrial Control Systems by Kaifeng Xie, Jinjing Wan, Lifeng Chen, Yi Wang

“…This paper proposes a test case generation method based on large language models (LLMs), which utilizes prompt templates and optimization algorithms to generate a code relevant to specific optimization passes, especially for real-time control logic and safety-critical modules unique to the industrial control field. …”
Get full text

Identification and mechanism analysis of biomarkers related to butyrate metabolism in COVID-19 patients by Wenchao Zhou, Hui Li, Juan Zhang, Changsheng Liu, Dan Liu, Xupeng Chen, Jing Ouyang, Tian Zeng, Shuang Peng, Fan Ouyang, Yunzhu Long, Yukun Li

“…Six machine learning algorithms were employed to determine the best model for identifying biomarkers, and receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic value of the biomarkers in COVID-19. …”
Get full text

Artificial Intelligence: A Review of Objective Grading and Quantification of Posterior Capsular Opacification by Saurabh Kushwaha, Rajat Chaudhary, Uma Devi

“…Here, we systematically reviewed several PCO imaging modalities, various existing AI algorithms, steps in building AI models and matrix evaluation in AI diagnosis of PCO. …”
Get full text

Leveraging advanced technologies for early detection and diagnosis of oral cancer: Warning alarm by Saantosh Saravanan, N. Aravindha Babu, Lakshmi T, Mukesh Kumar Dharmalingam Jothinathan

“…Specialized algorithms such as the Recombination-Based Improved Population Optimization Parallel Covariance Matrix Adaptation Evolution Strategy (RB-IPOP CMA-ES) allow for better accuracy of deep learning models, as this enhances the performance of developing models for early diagnosis of oral cancer. …”
Get full text

Advancements in Machine Learning (ML): Transforming the Future of Blood Cancer Detection and Outcome Prediction by Wiebke Rösler, Michael Roiss, Corinne Widmer

“…Recent studies demonstrate that ML algorithms can rapidly predict hematologic malignancies and patient outcomes, matching or exceeding the accuracy of experienced hematologists. …”
Get full text