TAL-SRX: an intelligent typing evaluation method for KASP primers based on multi-model fusion by Xiaojing Chen, Xiaojing Chen, Jingchao Fan, Jingchao Fan, Shen Yan, Longyu Huang, Longyu Huang, Longyu Huang, Guomin Zhou, Guomin Zhou, Jianhua Zhang, Jianhua Zhang

“…To address the above problems, we proposed a typing evaluation method for KASP primers by integrating deep learning and traditional machine learning algorithms, called TAL-SRX. First, three algorithms are used to optimize the performance of each model in the Stacking framework respectively, and five-fold cross-validation is used to enhance stability. …”
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An mRNA Vaccine for Herpes Zoster and Its Efficacy Evaluation in Naïve/Primed Murine Models by Linglei Jiang, Wenshuo Zhou, Fei Liu, Wenhui Li, Yan Xu, Zhenwei Liang, Man Cao, Li Hou, Pengxuan Liu, Feifei Wu, Aijun Shen, Zhiyuan Zhang, Xiaodi Zhang, Haibo Zhao, Xinping Pan, Tengjie Wu, William Jia, Yuntao Zhang

“…<b>Methods:</b> Various mRNA constructs were designed based on intracellular organelle-targeting strategies and AI algorithm-guided high-throughput automation platform screening and were then synthesized by in vitro transcription and encapsulated with four-component lipid nanoparticles (LNPs). …”
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Fuzzy-Based Fusion Model for β-Thalassemia Carriers Prediction Using Machine Learning Technique by Muhammad Ibrahim, Sagheer Abbas, Areej Fatima, Taher M. Ghazal, Muhammad Saleem, Meshal Alharbi, Fahad Mazaed Alotaibi, Muhammad Adnan Khan, Muhammad Waqas, Nouh Elmitwally

“…An efficient method of beta thalassemia is prenatal screening after couples have received counselling. …”
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An XGBoost-SHAP Model for Energy Demand Prediction With Boruta&#x2013;Lasso Feature Selection by Yiwen Wang, Weibin Cheng, Yuting Jin, Jifei Li, Yantian Yang, Shaobing Hu

“…This study proposes an interpretable ML framework for energy demand prediction based on the Boruta-Lasso two-stage feature selection model, extreme gradient boosting (XGBoost) regression model, grid search optimization algorithm, and Shapley additive explanations (SHAP) algorithm. …”
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Advancing Precision Medicine for Hypertensive Nephropathy: A Novel Prognostic Model Incorporating Pathological Indicators by Yunlong Qin, Jin Zhao, Yan Xing, Zixian Yu, Panpan Liu, Yuwei Wang, Anjing Wang, Yueqing Hui, Wei Zhao, Mei Han, Meng Liu, Xiaoxuan Ning, Shiren Sun

“…RSF and Cox regression were used to establish a renal prognosis prediction model based on the factors screened by the RSF algorithm. …”
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Ultrasound-based machine learning model to predict the risk of endometrial cancer among postmenopausal women by Yi-Xin Li, Yu Lu, Zhe-Ming Song, Yu-Ting Shen, Wen Lu, Min Ren

“…Radiomics features were extracted using Pyradiomics, and deep learning features were derived from convolutional neural network (CNN). Three models were developed: (1) R model: radiomics-based machine learning (ML) algorithms; (2) CNN model: image-based CNN algorithms; (3) DLR model: a hybrid model combining radiomics and deep learning features with ML algorithms. …”
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Development and application of an early prediction model for risk of bloodstream infection based on real-world study by Xiefei Hu, Shenshen Zhi, Yang Li, Yuming Cheng, Haiping Fan, Haorong Li, Zihao Meng, Jiaxin Xie, Shu Tang, Wei Li

“…This model is made publicly available as an online webpage tool for clinical use. …”
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An Updated Systematic Review on Asthma Exacerbation Risk Prediction Models Between 2017 and 2023: Risk of Bias and Applicability by Liu A, Zhang Y, Yadav CP, Chen W

“…We then applied the Prediction Risk of Bias Assessment tool (PROBAST) to assess the risk of bias and applicability of the included models.Results: Of 415 studies screened, 10 met eligibility criteria, comprising 41 prediction models. …”
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Development of an Efficient and Generalized MTSCAM Model to Predict Liquid Chromatography Retention Times of Organic Compounds by Mengdie Fan, Chenhui Sang, Hua Li, Yue Wei, Bin Zhang, Yang Xing, Jing Zhang, Jie Yin, Wei An, Bing Shao

“…The results demonstrate that this model achieves an R2 of 0.98 and an average prediction error of 23 s, outperforming currently published models. …”
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Risk Prediction of Liver Injury in Pediatric Tuberculosis Treatment: Development of an Automated Machine Learning Model by Zeng Y, Lu H, Li S, Shi QZ, Liu L, Gong YQ, Yan P

“…After the features were screened by univariate risk factor analysis, AutoML technology was used to establish predictive models. …”
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Development of a deep learning model for automated detection of calcium pyrophosphate deposition in hand radiographs by Thomas Hügle, Elisabeth Rosoux, Guillaume Fahrni, Deborah Markham, Tobias Manigold, Fabio Becce

“…The algorithm could be used to screen larger OA or RA databases or electronic medical records for CPPD cases. …”
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Identification of the Optimal Model for the Prediction of Diabetic Retinopathy in Chinese Rural Population: Handan Eye Study by Shanshan Jin, Xu Zhang, Hanruo Liu, Jie Hao, Kai Cao, Caixia Lin, Mayinuer Yusufu, Na Hu, Ailian Hu, Ningli Wang

“…To identify an optimal model for diabetic retinopathy (DR) prediction in Chinese rural population by establishing and comparing different algorithms based on the data from Handan Eye Study (HES). …”
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Detection of Hepatocellular Carcinoma Using Optimized miRNA Combinations and Interpretable Machine Learning Models by Zhengwu Long, Lisheng Zhang

“…Early screening to improve the survival rate of hepatocellular carcinoma (HCC) patients remains a critical clinical challenge. …”
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Development and validation of a risk prediction model for depression in patients with chronic obstructive pulmonary disease by Tong Feng, PeiPei Li, Ran Duan, Zhi Jin

“…Objective This study aimed to develop a machine learning-based model to predict depression risk in COPD patients, utilizing interpretable features from clinical and demographic data to support early intervention. …”
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Airfoil Optimization Design of Vertical-Axis Wind Turbine Based on Kriging Surrogate Model and MIGA by Quan Wang, Zhaogang Zhang

“…In response to this challenge, this study constructed a collaborative optimization framework based on the Kriging surrogate model and the multi-island genetic algorithm (MIGA). …”
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Artificial Intelligence and Machine Learning Models for Predicting Drug-Induced Kidney Injury in Small Molecules by Mohan Rao, Vahid Nassiri, Sanjay Srivastava, Amy Yang, Satjit Brar, Eric McDuffie, Clifford Sachs

“…Machine learning (ML) models were developed using four algorithms: Ridge Logistic Regression (RLR), Support Vector Machine (SVM), Random Forest (RF), and Neural Network (NN). …”
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A warning model for predicting patient admissions to the intensive care unit (ICU) following surgery by Li Li, Hongye He, Linjun Xiang, Yongxiang Wang

“…LASSO regression and random forest algorithms were used to screen clinical variables related to postoperative ICU admission. …”
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Machine learning-based prognostic prediction model of pneumonia-associated acute respiratory distress syndrome by Jing Lv, Juan Chen, Meijun Liu, Xue Dai, Wang Deng

“…The AUC value, AP value, accuracy, sensitivity, specificity, Brier score, and F 1 score were used to evaluate the performance of the models and pick the optimal model. Finally, the SHAP feature importance map was drawn to explain the optimal model.Results10 key variables, namely LAR, Lac, pH, age, PO2/FiO2, ALB, BMI, TP, PT, DBIL were screened using the filtration method. …”
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Deep Learning Classification of Systemic Sclerosis Skin Using the MobileNetV2 Model by Metin Akay, Yong Du, Cheryl L. Sershen, Minghua Wu, Ting Y. Chen, Shervin Assassi, Chandra Mohan, Yasemin M. Akay

“…We also utilized the MobileNetV2 model to analyze an additional dataset of images and classified them as normal, early (mid and moderate) SSc or late (severe) SSc skin images. …”
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A deep learning model to predict Ki-67 positivity in oral squamous cell carcinoma by Francesco Martino, Gennaro Ilardi, Silvia Varricchio, Daniela Russo, Rosa Maria Di Crescenzo, Stefania Staibano, Francesco Merolla

“…Aside from classification, detection, and segmentation models, predictive models are gaining traction since they can impact diagnostic processes and laboratory activity, lowering consumable usage and turnaround time. …”
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