Impact of ITH on PRAD patients and feasibility analysis of the positive correlation gene MYLK2 applied to PRAD treatment by Chuanyu Ma, Chuanyu Ma, Guandu Li, Xiaohan Song, Xiaochen Qi, Tao Jiang

“…GO and KEGG pathway enrichment analyses were performed on these 103 positively correlated differentially expressed genes, and the proportion and type of tumour-infiltrating immune cells were assessed by TIMER, CIBERSORT, CIBERSORT-ABS, QUANTISEQ, MCPCOUNTER, XCELL and EPIC algorithms in patients. In addition, we calculated the relevance of immunotherapy and predicted various drugs that might be used for treatment and evaluated the predictive power of survival models under multiple machine learning algorithms through the training set TCGA-PRAD versus the validation set PRAD-FR cohort. …”
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Focusing on scRNA-seq-Derived T Cell-Associated Genes to Identify Prognostic Signature and Immune Microenvironment Status in Low-Grade Glioma by Jiayu Wen, Qiaoyi Huang, Jiuxiu Yao, Wei Wei, Zehui Li, Huiqin Zhang, Surui Chang, Hui Pei, Yu Cao, Hao Li

“…In addition, bulk RNA data of 975 LGG samples were collected for model construction. Algorithms such as TIMER, CIBERSORT, QUANTISEQ, MCPCOUTER, XCELL, and EPIC were used to depict the tumor microenvironment landscape. …”
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CNN-Based Medical Ultrasound Image Quality Assessment by Siyuan Zhang, Yifan Wang, Jiayao Jiang, Jingxian Dong, Weiwei Yi, Wenguang Hou

“…At last, some tests are taken to evaluate the IQA models. They show that the CNN-based IQA is feasible and effective.…”
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Advances in the application of machine learning technology in the field of environmental health by ZHENG Yu, LI Cheng, HU Guiping, JIA Guang

“…However, the application of ML technology in the field of environmental health still faces challenges such as data quality, model interpretability, and interdisciplinary cooperation. …”
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Serum Lipid Biomarkers for the Diagnosis and Monitoring of Neuromyelitis Optica Spectrum Disorder: Towards Improved Clinical Management by Li R, Wang J, Wang J, Xie W, Song P, Zhang J, Xu Y, Tian D, Wu L, Wang C

“…Subsequently, we validated the candidate biomarkers in the retrospective cohort and developed diagnostic models using a random forest algorithm. The association between these lipid biomarkers and disease activity was further evaluated in longitudinal analysis.Results: Our analysis identified a panel of serum lipid-related biomarkers that demonstrated significant differences between NMOSD patients and controls. …”
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Study on classification of aluminum plastic packaging tablets for drugs based on SOM-FDA using XRF spectroscopy(基于SOM-FDA利用XRF对药品铝塑包装片的分类) by 姜红(JIANG Hong), 康瑞雪(KANG Ruixue), 郝小辉(HAO Xiaohui)

“…The established classification model is scientifically accurate and can provide assistance for public security organs in large-scale screening, determining investigation directions, and shortening investigation time.…”
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Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective stu... by Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen

“…Internal validation employed ROC analysis and calibration curves, while Shapley Additive Explanations (SHAP) values interpreted feature importance in the optimal model.ResultsAmong 2,921 screened patients, 1,272 met inclusion criteria. …”
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A reproducible approach for the use of aptamer libraries for the identification of Aptamarkers for brain amyloid deposition based on plasma analysis. by Cathal Meehan, Soizic Lecocq, Gregory Penner

“…Eight aptamers were identified as a result of the selection process and screened across 390 plasma samples by qPCR assay. Results were analysed using multiple machine learning algorithms from the Scikit-learn package along with clinical variables including cognitive status, age and sex to create predictive models. …”
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Utilising AI technique to identify depression risk among doctoral students by Changhong Teng, Chunmei Yang, Qiushi Liu

“…Based on the data from the 2019 Nature Global Doctoral Student Survey, we first screened 13 highly relevant features from a total of 37 features potentially related to the risk of depression among doctoral students by Random Forest algorithm. …”
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Predicting Affinity Through Homology (PATH): Interpretable binding affinity prediction with persistent homology. by Yuxi Long, Bruce R Donald

“…Compared to current binding affinity prediction algorithms, PATH+ shows similar or better accuracy and is more generalizable across orthogonal datasets. …”
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3D Reconstruction of the Human Colon From Capsule Endoscope Video by Pal Anders Floor, Ivar Farup, Marius Pedersen

“…As capsule endoscope images contain distortion and artifacts non-ideal for many 3D reconstruction algorithms, the problem is challenging. However, recent developments of virtual graphics-based models of the human gastrointestinal system, where distortion and artifacts can be enabled or disabled, make it possible to “dissect” the problem. …”
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Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome by Ge Jin, Xiaomei Fan, Xiaoliang Liang, Honghong Dai, Jun Wang

“…The risk score model constructed based on these biomarkers could effectively predict the survival rate of cervical cancer patients (AUC >0.6 for 1/3/5 years). …”
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Neutrophil extracellular traps-related genes contribute to sepsis-associated acute kidney injury by Tang Shaoqun, Yu Xi, Wang Wei, Luo Yaru, Lei Shaoqing, Qiu Zhen, Yang Yanlin, Sun Qian, Xia Zhongyuan

“…Differentially expressed genes were screened by “limma” package in R. Least absolute shrinkage and selection operator algorithm was applied to identify the hub genes. …”
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Application of Elastic networks and Bayesian networks to explore influencing factors associated with arthritis in middle-aged and older adults in the Chinese community by Tao Zhong, Tianlun Li, Jiapei Hu, Jiayi Hu, Li Jin, Yuxuan Xie, Bin Ma, Bin Ma, Dailun Hu

“…First, Elastic networks (ENs) were used to screen for features closely associated with arthritis, and we subsequently incorporated these features into the construction of the BNs model. …”
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Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…A series of machine learning algorithms was used to screen two feature genes (ETS1 and IL7R) to establish the diagnostic model, which exhibited satisfactory diagnostic efficiency. …”
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Real-World Parkinson’s Hand Tremor Detection Using Ensemble Learning Techniques by Sungwook Hur, Jieming Zhang, Moon-Hyun Kim, Tai-Myoung Chung

“…Our method enables more accurate detection of subtle tremor patterns in real-world conditions compared to conventional methods. …”
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Mitochondrial-Localized Protein Transcript Abundance can Predict the Prognosis of Endometrial Carcinoma: A Retrospective Analysis by Weifei Liang, Hong Lin, Donglin Sun, Minghui Tang

“…Moreover, a nomogram was constructed through the combination of the scoring algorithm and the patient’s clinical features. Conclusions: The scoring algorithm based on mitochondrial gene expression can assist clinicians in predicting the postoperative survival rate of patients, allowing them to devise more precise treatment programs.…”
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Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine... by Chenghui Cao, Chenghui Cao, Wenwu Liu, Xin Guo, Shuwei Weng, Yang Chen, Yonghong Luo, Shuai Wang, Botao Zhu, Botao Zhu, Yuxuan Liu, Yuxuan Liu, Daoquan Peng

“…This analysis was followed by a series of in-depth investigations, including protein–protein interaction (PPI), correlation analysis, and functional enrichment analysis, to uncover the molecular interactions and pathways at play. To screen for biomarkers for diagnosis, we applied machine learning algorithm to identify hub genes and constructed a clinical predictive model. …”
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Implementation costs and cost-effectiveness of ultraportable chest X-ray with artificial intelligence in active case finding for tuberculosis in Nigeria. by Tushar Garg, Stephen John, Suraj Abdulkarim, Adamu D Ahmed, Beatrice Kirubi, Md Toufiq Rahman, Emperor Ubochioma, Jacob Creswell

“…We provide implementation cost and cost-effectiveness estimates of different screening algorithms using symptoms, CXR and AI in Nigeria. …”
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AI-based classification of anticancer drugs reveals nucleolar condensation as a predictor of immunogenicity by Giulia Cerrato, Peng Liu, Liwei Zhao, Adriana Petrazzuolo, Juliette Humeau, Sophie Theresa Schmid, Mahmoud Abdellatif, Allan Sauvat, Guido Kroemer

“…Conclusions We developed AI-based algorithms for predicting CON-inducing drugs based on molecular descriptors and their validation using automated micrographs analysis, offering a new approach for screening ICD inducers with minimized adverse effects in cancer therapy.…”
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