A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data by Fengchun Ren, Xiao Zhao, Qin Yang, Huaqiang Liao, Yudong Zhang, Xuemei Liu

“…Ultimately, a user-friendly webserver was deployed for the predictive model and is freely accessed at http://bio-medical.online/admxp/.DiscussionThe associated webserver enables accessible risk screening and underpins precision prevention strategies in aging populations.…”
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Empowering Healthcare: TinyML for Precise Lung Disease Classification by Youssef Abadade, Nabil Benamar, Miloud Bagaa, Habiba Chaoui

“…These findings highlight the potential of TinyML to provide accessible, reliable, and real-time diagnostic tools, particularly in remote and underserved areas, demonstrating the transformative impact of integrating advanced AI algorithms into portable medical devices. This advancement facilitates the prospect of automated respiratory health screening using lung sounds.…”
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Few-Shot Intelligent Anti-Jamming Access with Fast Convergence: A GAN-Enhanced Deep Reinforcement Learning Approach by Tianxiao Wang, Yingtao Niu, Zhanyang Zhou

“…The method constructs a Generative Adversarial Network (GAN) to learn the time–frequency distribution characteristics of short-period jamming and to generate high-fidelity mixed samples. Furthermore, it screens qualified samples using the Pearson correlation coefficient to form a sample set, which is input into the DQN network model for pre-training to expand the experience replay buffer, effectively improving the convergence speed and decision accuracy of DQN. …”
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Recent Trends and Advances in Utilizing Digital Image Processing for Crop Nitrogen Management by Bhashitha Konara, Manokararajah Krishnapillai, Lakshman Galagedara

“…In addition, image data using more variables as model inputs, including agriculture sensors and meteorological data, have increased prediction accuracy. …”
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Adaptive Feature Selection of Unbalanced Data for Skiing Teaching by Tao Feng

“…If the features are not selected, the model may overly rely on the features of common actions and ignore the features of difficult actions. …”
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Machine Learning and Interpretability Study for Predicting 30-Day Unplanned Readmission Risk of Schizophrenia: A Retrospective Study by Tan Y, Chen G, Wang S, Zhan X, Cheng R, Qiao L, Zhang Z, Liu Y

“…Models were constructed after screening variables using the multiple linear regression and feature importance methods. …”
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Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy by Wuyuan Liao, Wuyuan Liao, Wuyuan Liao, Xinwei Zhou, Xinwei Zhou, Hansen Lin, Hansen Lin, Zihao Feng, Zihao Feng, Xinyan Chen, Yuhang Chen, Yuhang Chen, Minyu Chen, Minyu Chen, Mingjie Lin, Mingjie Lin, Gaosheng Yao, Gaosheng Yao, Jinwei Chen, Jinwei Chen, Haoqian Feng, Haoqian Feng, Yinghan Wang, Yinghan Wang, Zhiping Tan, Zhiping Tan, Youyan Tan, Jun Lu, Jun Lu, Pengju Li, Pengju Li, Jinhuan Wei, Jinhuan Wei, Li Luo, Li Luo, Liangmin Fu, Liangmin Fu, Liangmin Fu

“…By incorporating the interaction between TMB and the TME, our model provides a more accurate prediction of patient prognosis and treatment response across multiple cancer types. …”
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Sialyltransferase-related genes as predictive factors for therapeutic response and prognosis in cervical cancer by Jia Shao, Can Zhang, Yaonan Tang, Aiqin He, Xiangyan Cheng

“…Cox regression analysis and “glmnet” R package were applied to establish the relevant risk model. “MCPcounter” R package, ESTIMATE algorithm and TIMER online tools were used to depict the tumor immune microenvironment in CC. …”
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Exploring the role of repetitive negative thinking in the transdiagnostic context of depression and anxiety in children by Kuiliang Li, Lei Ren, Xiao Li, Chang Liu, Xuejiao Tan, Ming Ji, Xi Luo

“…Network analysis revealed that RNT’s core features exhibited the highest bridge betweenness and bridge expected influence, indicating a critical mediating role in the co-occurrence of symptoms. The random forest model showed optimal predictive performance (AUC = 0.90, recall = 0.95), supporting its applicability for early screening. …”
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Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer by Aiqin Zhao, Sufang Zhou, Xiaoyi Yang, Haiying Lu, Dan Zou, Xuan Zhang, Li Liu

“…To analyze the percentage of invading immune cells, the algorithms CIBERSORT, ESTIMATE, and xCell were used. …”
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PDP1 related ferroptosis risk signature indicates distinct immune microenvironment and prognosis of breast cancer patients by Yufeng Wang, Huifen Dang, Gongjian Zhu, Yingxia Tian

“…LASSO Cox regression was utilized to screen genes to build a RiskScore model, and survival analysis were performed to investigate the reliability in BC prognosis. …”
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Joint analysis of single-cell RNA sequencing and bulk transcriptome reveals the heterogeneity of the urea cycle of astrocytes in glioblastoma by Minfeng Tong, Qi Tu, Lude Wang, Huahui Chen, Xing Wan, Zhijian Xu

“…For bulk RNA-seq, univariate Cox and LASSO analyses were undertaken to screen prognostic genes, while multivariate Cox regression analysis was applied to set up a prognostic model. …”
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Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. by Katherine R Bull, Andrew J Rimmer, Owen M Siggs, Lisa A Miosge, Carla M Roots, Anselm Enders, Edward M Bertram, Tanya L Crockford, Belinda Whittle, Paul K Potter, Michelle M Simon, Ann-Marie Mallon, Steve D M Brown, Bruce Beutler, Christopher C Goodnow, Gerton Lunter, Richard J Cornall

“…Forward genetics screens with N-ethyl-N-nitrosourea (ENU) provide a powerful way to illuminate gene function and generate mouse models of human disease; however, the identification of causative mutations remains a limiting step. …”
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Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus by Fangyu Li, Rui Li, Hongjun Deng

“…The LASSO algorithm and ROC curve identified Retinol Dehydrogenase 10 (RDH10) as the best diagnostic gene for MASLD and T2DM. …”
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Prospective Validation and Usability Evaluation of a Mobile Diagnostic App for Obstructive Sleep Apnea by Pedro Amorim, Daniela Ferreira-Santos, Marta Drummond, Pedro Pereira Rodrigues

“…Current guidelines recommend the development of clinical prediction algorithms in screening prior to PSG. A recent intuitive and user-friendly tool (OSABayes), based on a Bayesian network model using six clinical variables, has been proposed to quantify the probability of OSA. …”
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Inflammation-related 5-hydroxymethylation signatures as markers for clinical presentations of coronary artery disease by Jing Xu, Hangyu Chen, Jingang Yang, Yanmin Yang, Yuan Wu, Jun Zhang, Jiansong Yuan, Tianjie Wang, Tao Tian, Jia Li, Xueyan Zhao, Xiaojin Gao, Jie Lu, Lin Li, Lei Zhang, Xuehui Li, Long Chen, Chuan He, Chaoran Dong, Jian Lin, Weixian Yang, Yuejin Yang

“…Using machine learning algorithms, we identified inflammation-related 5hmC modifications associated with disease severity and constructed a classification model based on key hydroxymethylated markers. …”
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Machine Learning–Based Prediction of Early Complications Following Surgery for Intestinal Obstruction: Multicenter Retrospective Study by Pinjie Huang, Jirong Yang, Dizhou Zhao, Taojia Ran, Yuheng Luo, Dong Yang, Xueqin Zheng, Shaoli Zhou, Chaojin Chen

“…ConclusionsWe have developed and validated a generalizable random forest model to predict postoperative early complications in patients undergoing intestinal obstruction surgery, enabling clinicians to screen high-risk patients and implement early individualized interventions. …”
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Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization by Riyadh M. Alzahrani, Mohamed Yacin Sikkandar, S. Sabarunisha Begum, Ahmed Farag Salem Babetat, Maryam Alhashim, Abdulrahman Alduraywish, N. B. Prakash, Eddie Y. K. Ng

“…An Enhanced Particle Swarm Optimization (EPSO) algorithm is integrated to automatically fine-tune CNN hyperparameters, thereby minimizing manual effort and enhancing computational efficiency. …”
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Golden eagle optimized CONV-LSTM and non-negativity-constrained autoencoder to support spatial and temporal features in cancer drug response prediction by Wesam Ibrahim Hajim, Suhaila Zainudin, Kauthar Mohd Daud, Khattab Alheeti

“…Advanced machine learning (ML) and deep learning (DL) methods have recently been utilized in Drug Response Prediction (DRP), and these models use the details from genomic profiles, such as extensive drug screening data and cell line data, to predict the response of drugs. …”
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Leveraging automated time-lapse microscopy coupled with deep learning to automate colony forming assay by Anusha Klett, Anusha Klett, Dennis Raith, Dennis Raith, Paula Silvestrini, Paula Silvestrini, Paula Silvestrini, Matías Stingl, Jonas Bermeitinger, Avani Sapre, Avani Sapre, Avani Sapre, Martin Condor, Roman Melachrinos, Mira Kusterer, Alexandra Brand, Guido Pisani, Guido Pisani, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Marie Follo, Marie Follo, Jesús Duque-Afonso, Roland Mertelsmann, Roland Mertelsmann

“…Brightfield images were used to train a YOLOv8 object detection network, achieving a mAP50 score of 86% for identifying single cells, clusters, and colonies, and 97% accuracy for Z-stack colony identification with a multi-object tracking algorithm. The detection model accurately identified the majority of objects in the dataset.ResultsThis AI-assisted CFA was successfully applied for density optimization, enabling the determination of seeding densities that maximize plating efficiency (PE), and for IC50 determination, offering an efficient, less labor-intensive method for testing drug concentrations. …”
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