Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…Interventions Participants were block randomised by a computer algorithm (stratified by severity and centre) to one of three trial arms: (1) usual care, (2) usual care + internet intervention and (3) usual care + internet intervention + telephone support. …”
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Psychometric properties of the German version of the Traumatic Grief Inventory-Self Report Plus (TGI-SR+) by Julia Treml, Viktoria Schmidt, Elmar Braehler, Matthias Morfeld, Anette Kersting

“…Despite the same name, both versions of PGD differ in symptom count, content, and diagnostic algorithm. A single instrument to screen for both PGD diagnoses is critical for bereavement research and care. …”
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Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach by Huali Jiang, Weijie Chen, Benfa Chen, Tao Feng, Heng Li, Dan Li, Shanhua Wang, Weijie Li

“…Machine learning algorithms (Support Vector Machine (SVM), Random Forest (RF) and Least Absolute Shrinkage and Selection Operator (LASSO)) were applied to identify hub genes. …”
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Leveraging Artificial Intelligence and Data Science for Integration of Social Determinants of Health in Emergency Medicine: Scoping Review by Ethan E Abbott, Donald Apakama, Lynne D Richardson, Lili Chan, Girish N Nadkarni

“…With a significant focus on the ED and notable NLP model performance, there is an imperative to standardize SDOH data collection, refine algorithms for diverse patient groups, and champion interdisciplinary synergies. …”
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MSGEGA: Multiscale Gaussian Enhancement and Global-Aware Network for Infrared Small Target Detection by Yuyang Xi, Liuwei Zhang, Ying Jiang, Feng Qian, Fanjiao Tan, Qingyu Hou

“…Specifically, the proposed method demonstrates significant advantages on the screened dataset, achieving an AUC of 0.992. At a detection rate of 0.871, it maintains a false alarm rate of 0.9<italic>e</italic>-5, outperforming all comparison algorithms. …”
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In silico assessment of biocompatibility and toxicity: molecular docking and dynamics simulation of PMMA-based dental materials for interim prosthetic restorations by Ravinder S. Saini, Rayan Ibrahim H. Binduhayyim, Vishwanath Gurumurthy, Abdulkhaliq Ali F. Alshadidi, Shashit Shetty Bavabeedu, Rajesh Vyas, Doni Dermawan, Punnoth Poonkuzhi Naseef, Seyed Ali Mosaddad, Artak Heboyan

“…The LigandScout was utilized for pharmacophore modeling, which employs a shape-based screening approach to identify potential ligand binding sites on protein targets. …”
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On the construction of a large-scale database of AI-assisted annotating lung ventilation-perfusion scintigraphy for pulmonary embolism (VQ4PEDB) by Amir Jabbarpour, Eric Moulton, Eric Moulton, Sanaz Kaviani, Sanaz Kaviani, Siraj Ghassel, Wanzhen Zeng, Wanzhen Zeng, Ramin Akbarian, Ramin Akbarian, Anne Couture, Aubert Roy, Richard Liu, Yousif A. Lucinian, Nuha Hejji, Nuha Hejji, Sukainah AlSulaiman, Sukainah AlSulaiman, Farnaz Shirazi, Farnaz Shirazi, Eugene Leung, Eugene Leung, Sierra Bonsall, Samir Arfin, Bruce G. Gray, Ran Klein, Ran Klein, Ran Klein, Ran Klein

“…The annotated data was then ingested into Deep Lake, a SQL-based database, for AI model training. Quality assurance involved manual inspections and algorithmic validation.ResultsA query of The Ottawa Hospital's data warehouse followed by initial data screening yielded 2,137 V/Q studies with 2,238 successfully retrieved as DICOM studies. …”
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Detecting and Explaining Postpartum Depression in Real-Time with Generative Artificial Intelligence by Silvia García-Méndez, Francisco de Arriba-Pérez

“…Moreover, it addresses the black box problem since the predictions are described to the end users thanks to the combination of LLMS with interpretable ML models (i.e. tree-based algorithms) using feature importance and natural language. …”
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Multidimensional Evaluation Framework and Classification Strategy for Low-Carbon Technologies in Office Buildings by Hongjiang Liu, Yuan Song, Yawei Du, Tao Feng, Zhihou Yang

“…The method includes four core components: (1) establishing three archetypal models—low-rise (H ≤ 24 m), mid-rise (24 m < H ≤ 50 m), and high-rise (50 m < H ≤ 100 m) office buildings—based on 99 office buildings in Beijing; (2) classifying 19 key technologies into three clusters—Envelope Structure Optimization, Equipment Efficiency Enhancement, and Renewable Energy Utilization—using bibliometric analysis and policy norm screening; (3) developing a four-dimensional evaluation framework encompassing Carbon Reduction Degree (CRD), Economic Viability Degree (EVD), Technical Applicability Degree (TAD), and Carbon Intensity Degree (CID); and (4) conducting a comprehensive quantitative evaluation using the AHP-entropy-TOPSIS algorithm. …”
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Community-based COVID-19 active case finding and rapid response in the Democratic Republic of the Congo: Improving case detection and response. by John Otokoye Otshudiema, Gervais Léon Tengomo Folefack, Justus M Nsio, Cathy H Kakema, Luigino Minikulu, Aimé Bafuana, Joel B Kosianza, Antoine K Mfumu, Edith Nkwembe, Yannick Munyeku-Bazitama, Sheila Makiala-Mandanda, Noé Guinko, Gisèle Mbuyi, Jean-Marie K Tshilumbu, Guy N Saidi, Moreau-Serge Umba-di-Masiala, Amos K Ebondo, Jean-Jacques Mutonj, Serge Kalombo, Jad Kabeya, Taty K Mawanda, Faustin N Bile, Gaby K Kasereka, Placide Mbala-Kingebeni, Steve Ahuka-Mundeke, Humphrey Cyprian Karamagi, Karl Njuwa Fai, Amédée Prosper Djiguimde

“…This pilot study was modeled on the DRC's National COVID-19 Response Plan and the COVID-19 Ag-RDT screening algorithm defined by the World Health Organization (WHO), with case findings implemented in 259 health areas, 39 health zones, and 9 provinces. …”
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A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database by Fei Wang, Xihao Wang, Zhigang Feng, Jun Li, Hailiang Xu, Hengming Lu, Lianqu Wang, Zhihui Li

“…Potential risk factors were initially screened applying the eXtreme Gradient Boosting (XGBoost) and Random Forest (RF) machine learning algorithms. …”
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Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma. by Xinmei Wang, Kwang Joo Kwak, Zhaogang Yang, Aili Zhang, Xiaoli Zhang, Rachael Sullivan, Dan Lin, Robert L Lee, Carlos Castro, Kalpana Ghoshal, Carl Schmidt, L James Lee

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DEPDC1B, CDCA2, APOBEC3B, and TYMS are potential hub genes and therapeutic targets for diagnosing dialysis patients with heart failure by Wenwu Tang, Wenwu Tang, Zhixin Wang, Xinzhu Yuan, Liping Chen, Haiyang Guo, Zhirui Qi, Ying Zhang, Xisheng Xie

“…In addition, we further explored potential mechanism and function of hub genes in HF of patients with MHD through GSEA, immune cell infiltration analysis, drug analysis and establishment of molecular regulatory network.ResultsTotally 23 candidate genes were screened out by overlapping 673 differentially expressed genes (DEGs) and 147 key module genes, of which four hub genes (DEPDC1B, CDCA2, APOBEC3B and TYMS) were obtained by two machine learning algorithms. …”
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Exploration of biomarkers for predicting the prognosis of patients with diffuse large B-cell lymphoma by machine-learning analysis by Shifen Wang, Hong Tao, Xingyun Zhao, Siwen Wu, Chunwei Yang, Yuanfei Shi, Zhenshu Xu, Dawei Cui

“…Moreover, four hub genes (CXCL9, CCL18, C1QA and CTSC) were significantly screened from the three datasets using RF algorithms. …”
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Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis by Ji Hui Fan, Xiao Min Li

“…Furthermore, three hub mRNAs (BOC, MLST8, and HMGCS2) from the CeRNA network were screened using LASSO algorithms. GSEA analysis revealed that hub mRNAs were implicated in a great deal of immune system responses and inflammatory pathways, including IL-5 production, MAPK signaling pathway, and JAK-STAT signaling pathway. …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Several electronic health record (EHR) algorithms have been developed to improve identification of patients with FH. …”
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Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation by Yuchen Cai, Tianyi Zhou, Xueyao Cai, Wenjun Shi, Hao Sun, Yao Fu

“…Hub genes were further screened and validated by multiple machine learning (ML) algorithms, followed by a comprehensive visualization of single-cell atlas and immune landscape. …”
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Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation by Li S, Zhu H, Zhai Q, Hou Y, Yang Y, Lan H, Jiang M, Xuan J

“…These discoveries were further validated in subsequent mouse models. An HFHC-induced NASH mouse model was used to validate the therapeutic effects and potential mechanisms of LQAtta on NASH.Results: From the UHPLC-MS/MS analysis of LQAtta, a total of 1518 chemical components were identified, with 106 of them being absorbed into the bloodstream. …”
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Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis by Weiwei Chen, Ying Zhu, Sihua Niu, Yan Zhou, Jian Chang, Shujie Gan

“…Finally, a DVT rat model was established to verify the expression of critical circRNAs and hub genes using real-time quantitative PCR.ResultsA total of 421 circRNAs and 1,082 mRNAs were differentially expressed in DVT. …”
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The performance of artificial intelligence in image-based prediction of hematoma enlargement: a systematic review and meta-analysis by Wenjing Fan, Zhiping Wu, Wangyang Zhao, Luzhu Jia, Shuze Li, Wei Wei, Xin Chen

“…Two reviewers independently screened the retrieved citations and extracted data. …”
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