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1081
Integrating equity, diversity, and inclusion throughout the lifecycle of artificial intelligence for healthcare: a scoping review.
Published 2025-07-01“…Previous research has shown that AI models improve when socio-demographic factors such as gender and race are considered. …”
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1082
Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke
Published 2025-08-01“…Functional enrichment, gene set enrichment analysis (GSEA), and protein–protein interaction (PPI) analyses were performed. Hub genes were screened using LASSO, RandomForest, and SVM-RFE algorithms. …”
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1083
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…The 10 MI-related hub MitoDEGs were then obtained by eight different algorithms. Immunoassays showed a significant increase in monocyte macrophage and T cell infiltration. …”
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1084
Integrative machine learning and molecular simulation approaches identify GSK3β inhibitors for neurodegenerative disease therapy
Published 2025-07-01“…Among all models, the Random Forest (RF) algorithm had the best prediction accuracy, with a value of 0.6832 on the test set and 0.7432 on the training set, and was employed to screen the target library of 11,032 phytochemicals. …”
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1085
Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking ap...
Published 2025-07-01“…As a result, the material–liquid ratio was significantly reduced from 100 g/mL to 32 g/mL, and the extraction efficiency was 1.332%, which was close to the predicted value of 1.346% in the response surface method, indicating that the algorithm model had a good fit. Next, a total of 738 compounds, including 161 terpenoids, 144 phenolic acids, 51 alkaloids, 24 flavonoids, 34 saccharides, 32 lignans and coumarins, 45 amino acids and derivatives, 23 organic acids, 134 lipids, 22 nucleotides and derivatives, and 59 other ingredients, were characterized from Scrophulariae Radix based on the accurate precursor and product ions, retention time, standards, fragmentation patterns, and previous publications. …”
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1086
Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.)
Published 2025-01-01“…Additionally, the least absolute shrinkage and selection operator (LASSO) regression algorithm in machine learning was used to screen transcription factors such as bHLH, WRKY, and MYB that influenced the expression of TaAkPHY genes. …”
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1087
The two ends of the spectrum: comparing chronic schizophrenia and premorbid latent schizotypy by actigraphy
Published 2025-05-01“…By applying model-explaining tools to the well-performing models, we could conclude the movement patterns and characteristics of the groups. …”
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1088
Deciphering the role of cuproptosis in the development of intimal hyperplasia in rat carotid arteries using single cell analysis and machine learning techniques
Published 2025-02-01“…Methods: We downloaded single-cell sequencing and bulk transcriptome data from the GEO database to screen for copper-growth-associated genes (CAGs) using machine-learning algorithms, including Random Forest and Support Vector Machine. …”
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1089
Optimized Landing Site Selection at the Lunar South Pole: A Convolutional Neural Network Approach
Published 2024-01-01“…Although intelligent algorithms have been increasingly investigated for this purpose, the application of deep learning techniques in landing site selection remains unexplored. …”
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1090
Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation
Published 2025-07-01“…Functional enrichment (GO/KEGG), protein-protein interaction (PPI) networks, and machine learning algorithms were applied to screen hub genes, validated by ROC curves. …”
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1091
Prediction and validation of anoikis-related genes in neuropathic pain using machine learning.
Published 2025-01-01“…We also used rats to construct an NP model and validated the analyzed hub genes using hematoxylin and eosin (H&E) staining, real-time polymerase chain reaction (PCR), and Western blotting assays.…”
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1092
Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma
Published 2024-12-01“…Univariate Cox regression analysis and Pearson correlation were used to screen for AMD1-related genes (ARGs). Multidimensional bioinformatic algorithms were utilized to establish a risk score model for ARGs. …”
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1093
Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning.
Published 2025-01-01“…Furthermore, we utilized least absolute shrinkage and selection operator (LASSO) regression and Random Forest (RF) algorithms to screen for hub genes. We then validated the expression of these hub genes and constructed nomograms for further validation. …”
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1094
LABORATORY OF CLINICAL IMMUNOLOGY N.V. SKLIFOSOVSKY RESEARCH INSTITUTE FOR EMERGENCY MEDICINE (HISTORY AND PRESENT)
Published 2016-03-01“…During 45 years of work of immunological service formed the algorithm of the adequate immunological screening was formed, number of innovative methods of diagnosis was developed, the ideology of post-test counseling of patients by immunologists was created, mathematical methods of storage, modeling and processing of research results was introduced. …”
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1095
Estimation of potato leaf area index based on spectral information and Haralick textures from UAV hyperspectral images
Published 2024-11-01“…Three types of spectral data—original spectral reflectance (OSR), first-order differential spectral reflectance (FDSR), and vegetation indices (VIs)—along with three types of Haralick textures—simple, advanced, and higher-order—were analyzed for their correlation with LAI across multiple growth stages. A model for LAI estimation in potato at multiple growth stages based on spectral and textural features screened by the successive projection algorithm (SPA) was constructed using partial least squares regression (PLSR), random forest regression (RFR) and gaussian process regression (GPR) machine learning methods. …”
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1096
Geographic variation in secondary metabolites contents and their relationship with soil mineral elements in Pleuropterus multiflorum Thunb. from different regions
Published 2024-09-01“…Conversely, a positive correlation was found between the contents of elements Na, Ce, Ti, and physcion and THSG-5, 2 components that exhibited higher levels in Deqing. Furthermore, an RF algorithm was employed to establish an interrelationship model, effectively forecasting the abundance of the majority of differential metabolites in HSW samples based on the content data of soil mineral elements. …”
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1097
Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis
Published 2025-07-01“…Using logistic regression, SVM, and LASSO regression algorithms, a successful early-diagnosis model for RS was developed, yielding 7 key genes: CNR1, KIT, HTR2A, DES, IL33, UCP2, and PPT1. …”
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1098
Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning
Published 2025-05-01“…Protein-Protein Interaction (PPI) network and machine learning algorithms, including Least Absolute Shrinkage and Selection Operator (LASSO) regression, Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Random Forest (RF), were applied to screen for signature MRDEGs. …”
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1099
Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy
Published 2025-07-01“…Through modelling the ATP6V0B cycling threshold, we reported 3 models with AUCs between 0.86 and 0.88, showcasing an enabling and clinically translatable liquid biopsy approach for early detection of pancreatic cancer using circulating EVs. …”
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1100
An EfficientNet integrated ResNet deep network and explainable AI for breast lesion classification from ultrasound images
Published 2025-06-01“…Explainable artificial intelligence‐based analysed the performance of trained models. After that, a new feature selection technique is proposed based on the cuckoo search algorithm called cuckoo search controlled standard error mean. …”
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