Microarray profile of circular RNAs identifies CBT15_circR_28491 and T helper cells as new regulators for deep vein thrombosis by Weiwei Chen, Ying Zhu, Sihua Niu, Yan Zhou, Jian Chang, Shujie Gan

“…Finally, a DVT rat model was established to verify the expression of critical circRNAs and hub genes using real-time quantitative PCR.ResultsA total of 421 circRNAs and 1,082 mRNAs were differentially expressed in DVT. …”
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人工智能融合临床与多组学数据在卒中防治及医药研发中的应用与挑战Applications and Challenges of Integrating Artificial Intelligence with Clinical and Multi-omics Data in Stroke Prevention, Treatment, and Pharmaceut... by 勾岚，姜明慧，姜勇，廖晓凌，李昊，张杰，程丝 (GOU Lan, JIANG Minghui, JIANG Yong, LIAO Xiaoling, LI Hao, ZHANG Jie, CHENG Si)

“…By integrating and analyzing clinical and multi-omics data, AI technology enhances the identification of high-risk populations, optimizes early diagnosis and risk assessment, enables precise subtyping of stroke, facilitates the screening of potential drug targets, and constructs prognostic prediction models. …”
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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers by Hengyan Zhang, Ye Zhou, Heguo Yan, Changxing Huang, Licong Yang, Yangwen Liu

“…We integrated the genes screened by three machine learning models (LASSO, SVM, and Random Forest), and CXCR4 was identified as a key gene with potential therapeutic value in DFUs. …”
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Identification and mechanism analysis of biomarkers related to butyrate metabolism in COVID-19 patients by Wenchao Zhou, Hui Li, Juan Zhang, Changsheng Liu, Dan Liu, Xupeng Chen, Jing Ouyang, Tian Zeng, Shuang Peng, Fan Ouyang, Yunzhu Long, Yukun Li

“…Six machine learning algorithms were employed to determine the best model for identifying biomarkers, and receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic value of the biomarkers in COVID-19. …”
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Use of artificial intelligence to support prehospital traumatic injury care: A scoping review by Jake Toy, Jonathan Warren, Kelsey Wilhelm, Brant Putnam, Denise Whitfield, Marianne Gausche‐Hill, Nichole Bosson, Ross Donaldson, Shira Schlesinger, Tabitha Cheng, Craig Goolsby

“…Conclusions A small but growing body of literature described AI models based on prehospital features that may support decisions made by dispatchers, Emergency Medical Services clinicians, and trauma teams in early traumatic injury care.…”
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Design, Fabrication, and Application of Large-Area Flexible Pressure and Strain Sensor Arrays: A Review by Xikuan Zhang, Jin Chai, Yongfu Zhan, Danfeng Cui, Xin Wang, Libo Gao

“…The rapid development of flexible sensor technology has made flexible sensor arrays a key research area in various applications due to their exceptional flexibility, wearability, and large-area-sensing capabilities. …”
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Exploring the predictive values of CRP and lymphocytes in coronary artery disease based on a machine learning and Mendelian randomization by Yuan Liu, Yuan Liu, Xin Yuan, Xin Yuan, Yu-Chan He, Yu-Chan He, Zhong-Hai Bi, Zhong-Hai Bi, Si-Yao Li, Si-Yao Li, Ye Li, Ye Li, Yan-Li Liu, Yan-Li Liu, Liu Miao, Liu Miao

“…Techniques employed included propensity score matching (PSM), logistic regression, lasso regression, and random forest algorithms (RF). Risk factors were assessed, and the sensitivity and specificity of the models were evaluated using receiver operating characteristic (ROC) curves. …”
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Integrating digital and narrative medicine in modern healthcare: a systematic review by Efthymia Efthymiou

“…The increasing integration of digital technologies in healthcare, such as electronic health records, telemedicine, and diagnostic algorithms, improved efficiency but raised concerns about the depersonalization of care. …”
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Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study by Duvern Ramiah, Sonwabile Ngcezu, Oluwatosin Ayeni, Okechinyere Achilonu, Mariam Adeleke, Theo Nair, Joseph Otten, Daniel Mmereki

“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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Locating and quantifying CH₄ sources within a wastewater treatment plant based on mobile measurements by J. Yang, Z. Xu, Z. Xia, Z. Xia, X. Pei, Y. Yang, B. Qiu, B. Qiu, S. Zhao, S. Zhao, Y. Zhang, Y. Zhang, Z. Wang, Z. Wang

“…We utilized a multi-source Gaussian plume model combined with a genetic algorithm inversion framework, designed to locate major sources within the plant and quantify the corresponding <span class="inline-formula">CH₄</span> emission fluxes. …”
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Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation by Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

“…Among the best-performing models with the least sensor data requirement, the ML algorithm predicted depressive symptoms with an accuracy of 80.6% (F1-score=0.76), high global MS symptom burden with an accuracy of 77.3% (F1-score=0.78), severe fatigue with an accuracy of 73.8% (F1-score=0.74), and poor sleep quality with an accuracy of 72.0% (F1-score=0.70). …”
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Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques by Liuqing Yang, Liuqing Yang, Liuqing Yang, Rui Xuan, Rui Xuan, Rui Xuan, Dawei Xu, Dawei Xu, Dawei Xu, Aming Sang, Aming Sang, Aming Sang, Jing Zhang, Jing Zhang, Jing Zhang, Yanfang Zhang, Xujun Ye, Xinyi Li, Xinyi Li, Xinyi Li

“…The utilization of the receiver operating characteristic curve in conjunction with the nomogram model served to authenticate the discriminatory strength and efficacy of the key genes. …”
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Forward first: Joystick interactions of toddlers during digital play. by Kimberly A Ingraham, Heather A Feldner, Katherine M Steele

“…These findings inform the design of assistive algorithms for joystick-enabled computer play and developmentally appropriate technologies for toddlers.…”
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Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases. by Hang Su, Na Rei, Lei Zhang, Jiaxiang Cheng

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Disentangling High-Paced Alternating I/O in Gaze-Based Interaction by Yulia G. Shevtsova, Artem S. Yashin, Sergei L. Shishkin, Anatoly N. Vasilyev

“…The two functions can be easily separated in some tasks, like eye typing, but more complex scenarios typically require users to perform additional actions to avoid misinterpreting their intent. …”
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Epidemiology and Association Rules Analysis for Pulmonary Tuberculosis Cases with Extrapulmonary Tuberculosis from Age and Gender Perspective: A Large-Scale Retrospective Multicent... by Wanli Kang, Jiajia Yu, Chen Liang, Quanhong Wang, Liang Li, Jian Du, Hongyan Chen, Jianxiong Liu, Jinshan Ma, Mingwu Li, Jingmin Qin, Wei Shu, Peilan Zong, Yi Zhang, Xiaofeng Yan, Zhiyi Yang, Zaoxian Mei, Qunyi Deng, Pu Wang, Wenge Han, Meiying Wu, Ling Chen, Xinguo Zhao, Lei Tan, Fujian Li, Chao Zheng, Hongwei Liu, Xinjie Li, Ertai A., Yingrong Du, Fenglin Liu, Wenyu Cui, Song Yang, Xiaohong Chen, Junfeng Han, Qingyao Xie, Yanmei Feng, Wenyu Liu, Peijun Tang, Jianyong Zhang, Jian Zheng, Dawei Chen, Xiangyang Yao, Tong Ren, Yan Li, Yuanyuan Li, Lei Wu, Qiang Song, Mei Yang, Jian Zhang, Yuanyuan Liu, Shuliang Guo, Kun Yan, Xinghua Shen, Dan Lei, Yanli Zhang, Youcai Li, Yongkang Dong, Shenjie Tang

“…The multivariable logistic regression models demonstrated that odds ratios of concurrent PTB-EPTB cases varied by gender and age group. …”
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Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning by Sizhang Wang, Xiaoyan Wang, Jing Xia, Qiang Mu

“…Then, four overlapping M1 macrophage infiltration-related genes (M1 MIRGs), namely CCDC69, PPP1R16B, IL21R, and FOXP3, were obtained using five machine-learning algorithms. Subsequently, nomogram models were constructed to predict the incidence of Her2-positive breast cancer patients. …”
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Validating the recording of exacerbations of asthma in electronic health records: a systematic review protocol by Jennifer K Quint, Elizabeth Moore, Zakariah Z Gassasse

“…However, previous studies found significant heterogeneity in the algorithms used to define asthma exacerbations. Validating definitions of asthma exacerbations in EHR will lead to more robust and comparable evidence in future research.Methods and analysis Medline and Embase will be searched for the key concepts relating to asthma exacerbations, EHR and validation. …”
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Prediction of traditional Chinese medicine for diabetes based on the multi-source ensemble method by Bin Yang, Qingyun Chi, Xiang Li, Jinglong Wang

“…The compound dataset from the TCMSP database is then used as testing data to predict and screen the active ingredients. The frequencies of occurrences of medicinal herbs corresponding to these three algorithms are obtained, each containing an active ingredient list. …”
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A scoping review on metrics to quantify reproducibility: a multitude of questions leads to a multitude of metrics by Rachel Heyard, Samuel Pawel, Joris Frese, Bernhard Voelkl, Hanno Würbel, Sarah McCann, Leonhard Held, Kimberley E. Wever, Helena Hartmann, Louise Townsin, Stephanie Zellers

“…The metrics were characterized based on type (formulas and/or statistical models, frameworks, graphical representations, studies and questionnaires, algorithms), input required and appropriate application scenarios. …”
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