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1241
Kun–Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile
Published 2025-08-01“…We aim to develop multimodal risk prediction models by integrating genomics and artificial intelligence algorithms. …”
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1242
Identification of hub genes for the diagnosis associated with heart failure using multiple cell death patterns
Published 2025-08-01“…Bioinformatics and machine learning algorithms were utilized to screen the HF key genes and PCD‐related HF hub genes, and an HF diagnostic model was constructed on this. …”
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1243
Research on implementation of interventions in tuberculosis control in low- and middle-income countries: a systematic review.
Published 2012-01-01“…Evaluations of diagnostic and screening algorithms were more frequent (n = 19) but geographically clustered and mainly of non-comparative design. …”
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1244
ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer
Published 2025-01-01“…Utilizing three distinct machine learning algorithms, we identified three signature genes-PBX1, IGHM, and CXCL13-that exhibited significant diagnostic value within the diagnostic model. …”
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1245
Problems and perspectives of family doctors training on the undergraduate stage
Published 2013-04-01“…For working on practical part of family doctors basic skills it is planned to organize educational and training center at the family ambulatory, and its equipment with the necessary visual means, phantoms, models, simulators, diagnostic, medical apparatus and instruments. …”
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1246
Advancement of artificial intelligence based treatment strategy in type 2 diabetes: A critical update
Published 2025-06-01“…At the same time, the rapidly increasing role of AI in diabetes care is woven into the story, mainly targeting how insulin therapy can be modified and personalized through algorithms and predictive modelling. It leaves a deep review of their pre-existing synergies, which helps understand how collaborative opportunities will unlock the future of T2DM care. …”
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1247
Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology
Published 2025-01-01“…We show that an algorithmic approach (Fragmenstein) that ‘stitches’ the ligand atoms from this structural information together can provide more accurate and reliable predictions for protein–ligand complex conformation than general methods such as pharmacophore-constrained docking. …”
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1248
Multi-Target Mechanism of Compound Qingdai Capsule for Treatment of Psoriasis: Multi-Omics Analysis and Experimental Verification
Published 2025-06-01“…CQC ingredients-targets network was constructed using these ingredients and their targets. Screening of CQC anti-psoriasis core targets using machine learning algorithm. …”
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1249
Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking ap...
Published 2025-07-01“…As a result, the material–liquid ratio was significantly reduced from 100 g/mL to 32 g/mL, and the extraction efficiency was 1.332%, which was close to the predicted value of 1.346% in the response surface method, indicating that the algorithm model had a good fit. Next, a total of 738 compounds, including 161 terpenoids, 144 phenolic acids, 51 alkaloids, 24 flavonoids, 34 saccharides, 32 lignans and coumarins, 45 amino acids and derivatives, 23 organic acids, 134 lipids, 22 nucleotides and derivatives, and 59 other ingredients, were characterized from Scrophulariae Radix based on the accurate precursor and product ions, retention time, standards, fragmentation patterns, and previous publications. …”
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1250
Transmitted drug resistance in the CFAR network of integrated clinical systems cohort: prevalence and effects on pre-therapy CD4 and viral load.
Published 2011-01-01“…Aggregate effects of mutations by drug class were estimated by fitting linear models of pVL and CD4 on weighted sums over TDR mutations according to the Stanford HIV Database algorithm. …”
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1251
Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.)
Published 2025-01-01“…Additionally, the least absolute shrinkage and selection operator (LASSO) regression algorithm in machine learning was used to screen transcription factors such as bHLH, WRKY, and MYB that influenced the expression of TaAkPHY genes. …”
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1252
Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms
Published 2025-06-01“…Differentially expressed genes (DEGs) between TNBC and other BRCA subtypes were intersected with T cell-related genes to identify candidate biomarkers. Machine learning algorithms were used to screen for key hub genes, which were then used to construct a logistic regression (LR) model. …”
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1253
A Deep Learning Method for Pneumoconiosis Staging on Chest X-Ray Under Label Noise
Published 2025-01-01“…The ambiguous properties of small opacities in pneumoconiosis chest radiographs can cause diagnostic drift, which in turn leads to the presence of noisy labels in the datasets collected from hospitals that can negatively impact the generalization of deep learning models. To tackle this issue, we propose COFINE, a novel coarse-to-fine noise-tolerant deep learning method for the staging of pneumoconiosis chest radiographs, which comprises two procedures: coarse screening and fine learning. …”
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1254
A nicotinamide metabolism-related gene signature for predicting immunotherapy response and prognosis in lung adenocarcinoma patients
Published 2025-02-01“…Four independent prognostic NMRGs (GJB3, CPA3, DKK1, KRT6A) were screened and used to construct a RiskScore model, which exhibited a strong predictive performance. …”
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1255
Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium
Published 2025-04-01“…We employed several machine learning algorithms, including least absolute shrinkage and selection operator and support vector machine–recursive feature elimination, to screen for key genes. …”
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1256
A systematic review of neural network applications for groundwater level prediction
Published 2025-08-01“…In conclusion, a hybrid metaheuristic algorithm produced more efficient results emphasizing their efficacy. …”
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1257
Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma
Published 2025-07-01“…We developed a novel machine learning framework that incorporated 12 machine learning algorithms and their 127 combinations to construct a consensus GPRS to screen biomarkers with diagnostic significance and clinical translation, which was assessed by the internal and external validation datasets. …”
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1258
Neutrophil- and Endothelial Cell-Derived Extracellular Microvesicles Are Promising Putative Biomarkers for Breast Cancer Diagnosis
Published 2025-02-01“…Machine learning approaches were employed to determine the performance of MVs to identify BC and to propose BC classifier algorithms. <b>Results:</b> Patients with BC had more neutrophil- and endothelial cell-derived MVs than controls before treatment. …”
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1259
Uso de inteligencia artificial para predecir complicaciones en cirugías de columna toracolumbar degenerativa: revisión sistemática
Published 2025-09-01“…Due to heterogeneity in samples, outcomes of interest, and algorithm evaluation metrics, a meta-analysis was not performed. …”
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1260
[Translated article] Use of artificial intelligence to predict complications in degenerative thoracolumbar spine surgery: A systematic review
Published 2025-09-01“…In 5 (41.6%) articles, the effectiveness of artificial intelligence predictive models was compared with conventional techniques. …”
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