Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization by Riyadh M. Alzahrani, Mohamed Yacin Sikkandar, S. Sabarunisha Begum, Ahmed Farag Salem Babetat, Maryam Alhashim, Abdulrahman Alduraywish, N. B. Prakash, Eddie Y. K. Ng

“…An Enhanced Particle Swarm Optimization (EPSO) algorithm is integrated to automatically fine-tune CNN hyperparameters, thereby minimizing manual effort and enhancing computational efficiency. …”
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Golden eagle optimized CONV-LSTM and non-negativity-constrained autoencoder to support spatial and temporal features in cancer drug response prediction by Wesam Ibrahim Hajim, Suhaila Zainudin, Kauthar Mohd Daud, Khattab Alheeti

“…Advanced machine learning (ML) and deep learning (DL) methods have recently been utilized in Drug Response Prediction (DRP), and these models use the details from genomic profiles, such as extensive drug screening data and cell line data, to predict the response of drugs. …”
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Automated interpretation of influenza hemagglutination inhibition (HAI) assays: Is plate tilting necessary? by Garrett Wilson, Zhiping Ye, Hang Xie, Steven Vahl, Erica Dawson, Kathy Rowlen

“…In a side-by-side comparison study performed during FDA's biannual serological screening process for influenza viruses, titer calls for more than 2200 serum samples were made by the Cypher One automated hemagglutination analyzer without tilting and by an expert human with tilting. …”
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Leveraging automated time-lapse microscopy coupled with deep learning to automate colony forming assay by Anusha Klett, Anusha Klett, Dennis Raith, Dennis Raith, Paula Silvestrini, Paula Silvestrini, Paula Silvestrini, Matías Stingl, Jonas Bermeitinger, Avani Sapre, Avani Sapre, Avani Sapre, Martin Condor, Roman Melachrinos, Mira Kusterer, Alexandra Brand, Guido Pisani, Guido Pisani, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Marie Follo, Marie Follo, Jesús Duque-Afonso, Roland Mertelsmann, Roland Mertelsmann

“…Brightfield images were used to train a YOLOv8 object detection network, achieving a mAP50 score of 86% for identifying single cells, clusters, and colonies, and 97% accuracy for Z-stack colony identification with a multi-object tracking algorithm. The detection model accurately identified the majority of objects in the dataset.ResultsThis AI-assisted CFA was successfully applied for density optimization, enabling the determination of seeding densities that maximize plating efficiency (PE), and for IC50 determination, offering an efficient, less labor-intensive method for testing drug concentrations. …”
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Immunotyping of thyroid cancer for clinical outcomes and implications by Jin Xu, Zhen Luo, Dayong Xu, Mujing Ke, Cheng Tan

“…Furthermore, the prognostic model’s utility in predicting immunotherapy response was analyzed. …”
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Opportunities and Challenges of Cardiovascular Disease Risk Prediction for Primary Prevention Using Machine Learning and Electronic Health Records: A Systematic Review by Tianyi Liu, Andrew J. Krentz, Zhiqiang Huo, Vasa Ćurčin

“…The synthesis underscores the superiority of ML in modeling intricate EHR-derived risk factors, facilitating precision-driven cardiovascular risk assessment. …”
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Efficient evidence selection for systematic reviews in traditional Chinese medicine by Yizhen Li, Zhe Huang, Zhongzhi Luan, Shujing Xu, Yunan Zhang, Lin Wu, Darong Wu, Dongran Han, Yixing Liu

“…Methods We integrated an established deep learning model (Evi-BERT combined rule-based method) with Boolean logic algorithms and an expanded retrieval strategy to automatically and accurately select potential evidence with minimal human intervention. …”
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TMSB4X is a regulator of inflammation-associated ferroptosis, and promotes the proliferation, migration and invasion of hepatocellular carcinoma cells by Linlin Tang, Yangli Jin, Jinxu Wang, Xiuyan Lu, Mengque Xu, Mingwei Xiang

“…Results 157 genes related to inflammation and ferroptosis in HCC were obtained by WGCNA. rLasso algorithm, with the highest C-index, screened out 29 hub genes, and this model showed good efficacy to predict the prognosis of HCC patients. …”
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Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications by Can Qi, Can Qi, Ziwei Zhao, Lin Chen, Le Wang, Yun Zhou, Guochen Duan, Guochen Duan

“…A total of five biomarkers,[Selenoprotein P1 (SEPP1), Fibrinogen-like protein 2 (FGL2), NK cell lectin-like receptor K1 (KLRK1), ATP-binding cassette transporters 6(ABCA6) and Galectins(GAL)], were screened, and a risk model based on the biomarkers was created. …”
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Novel insights of disulfidptosis-mediated immune microenvironment regulation in atherosclerosis based on bioinformatics analyses by Huanyi Zhao, Zheng Jin, Junlong Li, Junfeng Fang, Wei Wu, J. F. Fang

“…In addition, we established a foam cell model in vitro and an AS mouse model in vivo to verify the expressions of hub genes. …”
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Cadmium Exposure Disrupts Uterine Energy Metabolism and Coagulation Homeostasis During Labor in Institute of Cancer Research Mice: Insights from Transcriptomic Analysis by Yueyang Wang, Yichen Bai, Yi Wang, Yan Cai

“…This study is the first to establish a model of Cd exposure in the uterus of laboring mice and investigate the underlying metabolic mechanisms through transcriptomic analysis. …”
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Android malware detection based on APK signature information feedback by Xin-yu LIU, Jian WENG, Yue ZHANG, Bing-wen FENG, Jia-si WENG

“…A new malware detection method based on APK signature of information feedback (SigFeedback) was proposed.Based on SVM classification algorithm,the method of eigenvalue extraction adoped heuristic rule learning to sig APK information verify screening,and it also implemented the heuristic feedback,from which achieved the purpose of more accurate detection of malicious software.SigFeedback detection algorithm enjoyed the advantage of the high detection rate and low false positive rate.Finally the experiment show that the SigFeedback algorithm has high efficiency,making the rate of false positive from 13% down to 3%.…”
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Android malware detection based on APK signature information feedback by Xin-yu LIU, Jian WENG, Yue ZHANG, Bing-wen FENG, Jia-si WENG

“…A new malware detection method based on APK signature of information feedback (SigFeedback) was proposed.Based on SVM classification algorithm,the method of eigenvalue extraction adoped heuristic rule learning to sig APK information verify screening,and it also implemented the heuristic feedback,from which achieved the purpose of more accurate detection of malicious software.SigFeedback detection algorithm enjoyed the advantage of the high detection rate and low false positive rate.Finally the experiment show that the SigFeedback algorithm has high efficiency,making the rate of false positive from 13% down to 3%.…”
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Investigating the Complexity of Multidimensional Symptom Experiences in Patients With Cancer: Systematic Review of the Network Analysis Approach by Vincent Richard, Allison Gilbert, Emanuela Pizzolla, Giovanni Briganti

“…Several NA approaches were used: network visualization (n=1), Bayesian network (n=1), pairwise Markov random field and IsingFit method (n=1), unregularized Gaussian graphical model (n=2), regularized partial correlation network (n=6), network visualization and community NA (n=1), network visualization and Walktrap algorithm (n=1), undirected network model with the Fruchterman-Reingold and edge-betweenness approaches (n=4), biased correlation and concise pattern diagram (n=1), extended Bayesian information criterion graphical LASSO method (n=3), cross-lagged panel network (n=1), and unspecified NA (n=3). …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer by Jie Peng, Jiaao Sun, Youfeng Yu, Qihang Yuan, Yong Zhang

“…In the process of building prognostic models, we screened 33 core genes related to the prognosis of pancreatic cancer, and combined a series of machine learning algorithms to build the prognosis model of pancreatic cancer. …”
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Automated Detection of Reduced Ejection Fraction Using an ECG-Enabled Digital Stethoscope by Ling Guo, PhD, Gregg S. Pressman, MD, Spencer N. Kieu, BS, Scott B. Marrus, MD, PhD, George Mathew, PhD, John Prince, PhD, Emileigh Lastowski, MS, Rosalie V. McDonough, MD, MSc, Caroline Currie, BA, John N. Maidens, PhD, Hussein Al-Sudani, MD, Evan Friend, BA, Deepak Padmanabhan, MD, Preetham Kumar, MD, Edward Kersh, MD, Subramaniam Venkatraman, PhD, Salima Qamruddin, MD

“…Recently, electrocardiogram-based algorithms have shown promise in detecting ALVSD. Objectives: The authors developed and validated a convolutional neural network (CNN) model using single-lead electrocardiogram and phonocardiogram inputs captured by a digital stethoscope to assess its utility in detecting individuals with actionably low ejection fractions (EF) in a large cohort of patients. …”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…A high IoU value in medical imaging analysis reflects the model’s ability to accurately delineate object boundaries.ConclusionDeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. …”
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Prevention of Cardiometabolic Syndrome in Children and Adolescents Using Machine Learning and Noninvasive Factors: The CASPIAN-V Study by Hamid Reza Marateb, Mahsa Mansourian, Amirhossein Koochekian, Mehdi Shirzadi, Shadi Zamani, Marjan Mansourian, Miquel Angel Mañanas, Roya Kelishadi

“…We applied the XGBoost algorithm to analyze key noninvasive variables, including self-rated health, sunlight exposure, screen time, consanguinity, healthy and unhealthy dietary habits, discretionary salt and sugar consumption, birthweight, and birth order, father and mother education, oral hygiene behavior, and family history of dyslipidemia, obesity, hypertension, and diabetes using five-fold cross-validation. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. …”
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Retinal Microvascular Characteristics—Novel Risk Stratification in Cardiovascular Diseases by Alexandra Cristina Rusu, Klara Brînzaniuc, Grigore Tinica, Clément Germanese, Simona Irina Damian, Sofia Mihaela David, Raluca Ozana Chistol

“…This study aims to identify the retinal microvascular features associated with CHDs and evaluate their potential use in a CHD screening algorithm in conjunction with traditional risk factors. …”
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