Environmental DNA supports importance of heterogeneous pond landscapes for arthropod diversity conservation by Vera Zizka, Katharina Schwesig, Nele Engel, Norbert Hölzel, Christoph Scherber

“…Our study shows that systematic biodiversity management concepts both during active mining and at later stages of succession will be needed. Monitoring should go beyond just measuring taxonomic richness, including also assessments of community composition, the presence of rare and endangered taxa, and functional diversity.…”
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Enhancing Creativity and Validation in Explanatory Deep Learning-Based Symbolic Music Generation: A Hybrid Approach With LSTM and Genetic Algorithms by Ahmad Zainul Fanani, Arry Maulana Syarif, Ika Novita Dewi, Abdul Karim

“…The LSTM network produces initial compositions, and the GA module ensures compliance with musical rules, enhancing both explainability and creativity. The model successfully generates new bars and lines with notation sequences not found in the original dataset, indicating creative variation. …”
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Organic cation transporter 3 on neuronal mitochondria mediates MPP+-induced mitochondrial dysfunction and neurotoxicity in a TIMM22-dependent manner by Ao Guan, Sida Han, Suzhen Liang, Weiwei Shen, Min Guo, Mei Cui

“…Knockdown of the translocase of inner mitochondrial membrane 22 (TIMM22), an important component of the mitochondrial protein import apparatus, successfully reduced OCT3 levels on mitochondria without impairing mitochondrial morphology or mitochondrial membrane potential. …”
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Tumor-derived exosomal miR-1247-3p promotes angiogenesis in bladder cancer by targeting FOXO1 by Zonglai Liu, Dan Du, Shizhong Zhang

“…The interaction between miR-1247-3p and forkhead box protein O1 (FOXO1) was studied using luciferase reporter and RNA pull down assays. Exosomes were successfully isolated from T24, UM-UC-3, and SV-HUC-1 cells, as confirmed by corresponding identifications. …”
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Super-Resolution Three-Dimensional Topography Measurement Using Microsphere-Aided Broadband Light Interferometry by Keran Deng, Yangyi Liu, Fan Yang, Jian Huang, Lianghua Wen

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MSC-Derived Extracellular Vesicles Activate Mitophagy to Alleviate Renal Ischemia/Reperfusion Injury via the miR-223-3p/NLRP3 Axis by Zejia Sun, Zihao Gao, Jiyue Wu, Xiang Zheng, Shizhao Jing, Wei Wang

“…MSC-derived extracellular vehicles (EVs) exhibit a protective functional role in renal ischemia/reperfusion injury (RIRI). …”
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BMSC-derived exosomes promote osteoporosis alleviation via M2 macrophage polarization by Yanbin Zhang, Jing Bai, Bin Xiao, Chunyan Li

“…Real-time quantitative PCR was used to detect the expression of macrophage surface markers and tripartite motif (TRIM) family genes. …”
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Optimization in High-pressure Microfluidics Preparation of Black Pepper Essential Oil Nanoemulsion by Response Surface Methodology and Its Component Analysis by Yaxin TAN, Song WU, Hanyue YANG, Xiaoya YUAN, Yonggui PAN

“…The particle size of BPEO nanoemulsion prepared under these conditions was 126.64 nm and the polymer dispersity index (PDI) was 0.238. Most of the functional groups of Tween 80 and BPEO exist in the BPEO nanoemulsion, and the wavenumber changes of the characteristic absorption peaks were slightly small, which proved that BPEO was successfully wrapped in the droplet. …”
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Multimorbidity and associated outcomes among older adult inpatients with neurological disorders by Aroldo BACELLAR, Telma ASSIS, Bruno Bacellar PEDREIRA, Luan CÔRTES, Silas SANTANA, Osvaldo José Moreira do NASCIMENTO

“…Methods: We enrolled patients aged ≥60 years successively admitted to a tertiary medical center with NDs between January 1, 2009, and December 31, 2010. …”
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Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway. by Jing Zhang, Xuefeng Chen, Shilin Lv, Qingqing Hao

“…Protein expression levels of nuclear factor E2-related factor 2(Nrf2), heme oxygenase-1(HO-1), glutathione peroxidase 4(Gpx4) were detected by Western blot.<h4>Results</h4>In animals with chronic heart failure, Dapagliflozin improved cardiomyocyte hypertrophy, degeneration and necrosis. …”
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The clinical application of mitoxantrone hydrochloride tracing in endoscopic radical resection of thyroid carcinoma by Xiaozhou Cheng, Lijun Chen, Honggang Zang, Yaping Li

“…Postoperative metrics compared between the two groups included the number of central lymph nodes dissected, the number of metastatic lymph nodes, the incidence of parathyroid gland misdissection, serum parathyroid hormone (PTH) levels, and blood calcium levels. Both groups successfully completed the surgeries. The observation group exhibited a higher number of central lymph nodes dissected and metastatic lymph nodes detected compared to the control group (P < 0.05). …”
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Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis by Lei XiaoTian, Wu QiNan, Gan XiaGuang, Deng WuQuan, Chen Bing, Liang ZiWen

“…Our model of diabetic cardiomyopathy was constructed successfully. After being treated with exenatide, the adiponectin and HMW-adiponectin and the APPL1-AMPK-PPARα axis were increased, the NF-κB and the apoptosis were decreased, the cardiac function of the diabetic rats was improved, and these effects were independent of glucose control.…”
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Novel resistance to Cydia pomonella granulovirus (CpGV) in codling moth shows autosomal and dominant inheritance and confers cross-resistance to different CpGV genome groups. by Annette J Sauer, Eva Fritsch, Karin Undorf-Spahn, Petr Nguyen, Frantisek Marec, David G Heckel, Johannes A Jehle

“…Commercial Cydia pomonella granulovirus (CpGV) products have been successfully applied to control codling moth (CM) in organic and integrated fruit production for more than 30 years. …”
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Reduced representation sequencing reveals genetic diversity and adaptive genetic divergence in Calamus rhabdocladus by Rui Gu, Ruijing Xu, Songpo Wei, Pär K. Ingvarsson, Shaohui Fan, Guanglu Liu

“…The Latent Factor Mixed Model (LFMM) identified 955 loci significantly associated with environmental adaptation and successfully aligned 469 genes from related species, which were enriched in functional categories involving cell structure, carbohydrate metabolism, and protein degradation. …”
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Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study by Tinkara Srnovršnik, Bojana Pinter, Milena Horvat, Janja Snoj Tratnik, Ingrid Falnoga, Darja Mazej, Ivan Verdenik, Irma Virant-Klun

“…<b>Results:</b> In women with PCOS, lower Mo levels in whole blood (<i>p</i> = 0.024) and serum (<i>p</i> = 0.011) and higher serum Cu levels (<i>p</i> = 0.026) were detected when compared to healthy controls. Results of this study show that amendments in Cu and Mo levels might be related to altered kidney and liver function and disrupted hormonal balance in PCOS women. …”
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In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra... by Chiriapkin, A.S., Kodonidi, I.P., Abisalova, I.L., Diakova, I.N.

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Features of the morphological structure of plants and biochemical properties of introduced and domestic varieties of Cannabis sativa L. by А. С. Полякова, Л. М. Горшкова, Д. Б. Рахметов

“…Nowadays C. sativa is the main source of phyto material for industrial production of natural CBD. …”
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Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma by Mingjun Gao, Mengmeng Wang, Siding Zhou, Jiaqi Hou, Wenbo He, Yusheng Shu, Xiaolin Wang

“…Finally, we analyzed the expression of KRT81 in LUAD tissues and cell lines using qRT-PCR, WB, and IHC. Changes in KRT81 function in LUAD cells were detected by CCK-8, colony formation, wound healing, transwell, and flow cytometry. …”
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Identification of Cancer Stem Cell (CSC)-Associated Genes, Prognostic Value, and Candidate Drugs as Modulators of CSC-Associated Signaling in Carcinomas Through a Multiomics Data A... by Pallabi Mondal, Poulami Singh, Krishna Mahanti, Sankar Bhattacharyya

“…This ability of CSCs to escape immune responses makes the CSCs a primary source of functionally altered, immune-resistant, chemoresistant, aggressive tumor cells. …”
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Reduction of Total Phenols in Virgin Olive Oil as a Preservation Medium during Cold Storage of Whey Cheese and Tofu by Valerija Majetić Germek, Ivana Gobin, Doris Franjković, Marija Marković, Olivera Koprivnjak

“…Virgin olive oil, known as a good source of health-promoting hydrophilic phenols, is traditionally used as a medium for preserving various foods. …”
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