Transcriptional patterns of cancer-related genes in primary and metastatic tumours revealed by machine learning by Faeze Keshavarz-Rahaghi, Erin Pleasance, Steven J. M. Jones

“…Results Using random forest models, we successfully identified transcriptional patterns associated with the loss of wild-type activity in cancer-related genes across various tumour types. …”
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Use of Cidofovir for Safe Transplantation in a Toddler with Acute Liver Failure and Adenovirus Viremia by Vikram J. Christian, Raiya Sarwar, Joseph C. Resch, Sarah Lim, Arif Somani, Catherine Larson-Nath, Shane McAllister, Beth K. Thielen, Oyedele Adeyi, Srinath Chinnakotla, Heli Bhatt

“…Our patient received a successful liver transplant, cleared the viremia after 5 doses of cidofovir, and continues to maintain allograft function without signs of infection at the time of this report, 5 months posttransplant. …”
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Mixed eco-neighborhood: Matsaria as a model of post-industrial transformation by Iñigo Garcia Odiaga, Nekane Azpiazu Lejardi, Francisca Gual Ors

“…These guidelines arise from common patterns detected in successful processes of urban and industrial regeneration, demonstrating their capacity for transformation in non-specialized structures. …”
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Visualization of Molluscum Contagiosum Virus in FFPE Skin Sections Using NanoSuit‐CLEM: Ultrastructural Evidence of Viral Spread via Skin Barrier Disruption by Yuri Sakano, Hideya Kawasaki

“…While Melan‐A immunostaining successfully detected Henderson–Patterson bodies, it failed to identify mature MC virus particles. …”
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Geometric morphometric analysis of the condylus occipitalis and foramen magnum in sheep and goat by Ismail Demircioglu, Yasin Demiraslan, Funda Aksunger Karaavci, Iftar Gurbuz, Ozcan Ozgel

“…<p> <b>Conclusion: </b>As a result, the geometric morphometry method is regarded to be a useful tool for detecting changes in skull shape between species and can thus be used successfully for taxonomic, archaeological, and forensic research.…”
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Assembly and comparative analysis of the complete mitochondrial of Spodiopogon sagittifolius, an endemic and protective species from Yunnan, China by Chao Xu, Wei Bi, Ren-yi Ma, Pin-rong Li, Feng Liu, Zhen-wen Liu

“…Extensive RNA editing events were detected across 27 protein-coding genes, predominantly involving C-to-U conversions, with synonymous mutations accounting for 49.65% of the edits. …”
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Pacemaker migration into the peritoneal cavity in children: a case series by Nicole H. Chicoine, Patrick J. Javid, David H. Rothstein, Samuel E. Rice-Townsend, Kimberly J. Riehle, Terrence U. Chun, Sarah L.M. Greenberg

“…Migration was detected at the age of 17 years on a routine abdomen/chest x-ray, and was confirmed on a CT. …”
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Preparation of nanosized hypoxia-inducible factor 1α inhibitor and its application in reversing chemoresistance in colorectal cancer cells by ZHENG Chuanhao, DAN Ruijue, XI Xi

“…FYC-1 was also successfully prepared. When FYC-1 was interacted with HCT15 cells, FYC-1 could be better taken up by the cells, indicating that the amphiphilic MYC-1 could be better endocytosed into the cells to exert its function. …”
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Unawareness of the disease in patients with schizophrenia: diagnosis and insight-oriented psychotherapy by O. I. Osokina, B. B. Ivnyev, G. G. Putyatin, Ye. M. Denisov, S. G. Ushenin

“…A different predictive value of some insight components was found. There were detected correlations between a successful disease prognosis and a high degree of patient awareness of the disease symptoms (r = -0.318; p<0.05), the need for treatment (r = -0.603; p<0.05), the drug effect (r = -0.312; p<0.05) and a low awareness level of how people perceive the patient’s illness (r = 0.527; p<0.05) and its social consequences (r= 0.419; p<0.05). …”
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Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…Here, we established a monoclonal cell line that consistently expresses Cas9 and can be used for screens to determine gene function or antiviral activity. <b>Methods</b>: We used this system to perform the successful gene editing of seven genes and subsequent testing for potential antiviral effects, using a simple single-guide RNA (sgRNA) transfection and subsequent virus infection. …”
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Dynamic Monitoring of Goaf Stress Field and Rock Deformation Driven by Optical Diber Sensing Technology by Jing Chai, Zhe Yan, Yibo Ouyang, Dingding Zhang, Jianfeng Yang, Gaoyi Yang, Chenyang Ma

“…The developed stress inversion formula successfully predicted pressure distribution patterns within the goaf, achieving real-time monitoring capabilities. …”
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Patient and public involvement in the co-design and assessment of unobtrusive sensing technologies for care at home: a user-centric design approach by Jenny Sharma, Nazia Gillani, Imran Saied, Aaesha Alzaabi, Tughrul Arslan

“…Suggestions for refining the prototypes included adding functionality for detecting deviations in daily routines and integrating feedback mechanisms for caregivers. …”
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Long-Term Therapeutic Effects of ²²⁵Ac-DOTA-E[c(RGDfK)]₂ Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma by Mitsuyoshi Yoshimoto, Kohshin Washiyama, Kazunobu Ohnuki, Ayano Doi, Miki Inokuchi, Motohiro Kojima, Brian W. Miller, Yukie Yoshii, Anri Inaki, Hirofumi Fujii

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Effects of Debittering Treatments on Some Secondary Metabolites’ Bioaccessibility, Fatty Acid, and Aroma Profiles of Semidried Gemlik Variety Black Olives by Senanur Durgut Malçok, Cüneyt Tunçkal, Azime Özkan Karabacak, Gülderen Coşgun, Mehmet Torun, Canan Ece Tamer

“…In the evaluation of the fatty acid composition of raw and table olives, 11 different fatty acids including oleic, palmitic, linoleic, stearic, elaidic, palmitoleic, and arachidic were detected in all samples. A total of 57 aroma compounds were detected in the samples, of which 55 were successfully identified. …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…Current assessment tools fail to detect subtle abilities in CMC, hindering development of effective rehabilitation goals and interventions. …”
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Identification of a Rare Mutation in the SRD5A2 Gene in an Iranian Family with Sex Development Disorder by Atiyeh Ataei, Peyman Eshraghi, Atiyeh Eslahi, Zeinab Khazaei, Masoome Alerasool, Sara Jamali, Faranak Ghadamyari, Majid Mojarrad

“…According to WES result and Sanger sequencing a homozygote loss of function mutation (c.16C>T; p.Gln6Ter) in SRD5A2 has been detected. …”
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Synthesis of 2-Amino-4, 5-Diarylthiazole Derivatives and Evaluation of Their Anti-<i>Candida</i> Albicans Activity by Dongmei Gao, Lele Shi, Yuhang Huang, Yingmei Lv, Xuan Yang, Zhenting Du

“…Thus, <b>5a8</b> was synthesized successfully, giving anti-<i>Candida albicans</i> activity (MIC₈₀ = 9 μM) similar to that of a typical antifungal drug, fluconazole. …”
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History and prospects of flax genetic markers by Daiana A. Zhernova, Elena N. Pushkova, Tatiana A. Rozhmina, Elena V. Borkhert, Alexander A. Arkhipov, Alexander A. Arkhipov, Elizaveta A. Sigova, Elizaveta A. Sigova, Ekaterina M. Dvorianinova, Ekaterina M. Dvorianinova, Alexey A. Dmitriev, Alexey A. Dmitriev, Nataliya V. Melnikova

“…Flax (Linum usitatissimum L.) is known as a dual-purpose crop, producing both fiber and oil, which have a wide range of uses. Successful flax breeding requires knowledge on the genetic determinants of flax traits. …”
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Quantitative Proteomics Revealed the Molecular Regulatory Network of Lysine and the Effects of Lysine Supplementation on Sunit Skeletal Muscle Satellite Cells by Mingxu Wang, Fan Bai, Qinan Zhao, Jianan Shi, Yutian Hao, Jindi Wu

“…This study explored lysine (Lys)’s effects on SMSCs and their protein profiles in Sunit sheep. SMSCs were successfully isolated, assessing their survival and proliferation after Lys stimulation at varying concentrations using the CCK-8 assay. …”
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Scaling-up of carbon dots hydrothermal synthesis from sugars in a continuous flow microreactor system for biomedical application as in vitro antimicrobial drug nanocarrier by Siriboon Supajaruwong, Sirawich Porahong, Agung Wibowo, Yu-Sheng Yu, Mohd Jahir Khan, Pisut Pongchaikul, Pattaraporn Posoknistakul, Navadol Laosiripojana, Kevin C.-W. Wu, Chularat Sakdaronnarong

“…Carbon dots (CDs) are a new class of nanomaterials exhibiting high biocompatibility, water solubility, functionality, and tunable fluorescence (FL) property. …”
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