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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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1202
Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis
Published 2025-08-01“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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1203
Genome-wide identification and expression pattern analysis of NAC family in Taxus yunnanensis and the TyuNAC30 role in paclitaxel production
Published 2025-07-01“…Yeast one-hybrid and related assays revealed that TyuNAC30 functions as a negative regulator of TyuDBTNBT, a key enzyme gene in the paclitaxel biosynthetic pathway. …”
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1204
Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity
Published 2019-10-01“…Since the protein content of human urine is closely related to the peculiarity of the functioning of biological systems, its qualitative and quantitative characteristics are promising markers for control of various processes in organism. …”
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1205
Development of Integrated Neural Network Model for Identification of Fake Reviews in E-Commerce Using Multidomain Datasets
Published 2021-01-01“…Thus, developing a fake review detection system is ultimately required for E-commerce business. …”
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1206
Cutaneous Anthrax: What is the Hallmark?
Published 2024-10-01“…Clinical and serological examinations are the spearheads of early detection of anthrax cases. Prompt and appropriate management largely determines the success of therapy.…”
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1207
Cutaneous Anthrax: What is the Hallmark?
Published 2025-01-01“…Clinical and serological examinations are the spearheads of early detection of anthrax cases. Prompt and appropriate management largely determines the success of therapy. …”
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1208
Postimplementation Evaluation in Assisted Living Facilities of an eHealth Medical Device Developed to Predict and Avoid Unplanned Hospitalizations: Pragmatic Trial
Published 2024-12-01“…ConclusionsThe Presage Care system has been implemented with success in assisted living facilities. It was well accepted by coordinating nurses and performed well in predicting emergency hospitalizations. …”
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1209
Multimessenger Signatures of a Deformed Magnetar in Gamma-Ray Bursts
Published 2025-01-01“…We study the evolution of a newly formed magnetized neutron star (NS) as a power source of gamma-ray bursts (GRBs) in the light of both gravitational-wave (GW) and electromagnetic (EM) radiation. …”
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1210
Pearls on a String: Dark and Bright Galaxies on a Strikingly Straight and Narrow Filament
Published 2025-01-01“…We study the cold H i gas in a 1.3 Mpc section of the filament through H i 21 cm emission line observations and detect 11 H i sources, many more than expected from the H i mass function in a similar volume. …”
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1211
In situ, modeled, and earth observation monitoring of surface water availability in West African rangelands
Published 2025-06-01“…The 12 locations can function as sentinel ponds to monitor local water availability. …”
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1212
Subclinical Aortic Root Pathology in Close Relatives of Patients with Bicuspid Aortic Valve
Published 2013-12-01“…According to various sources, among the relatives of the first degree (FDR) of affinity the prevalence of BAV is 9.0-21.0%. …”
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1213
A universal ground test equipment design for the Chang’e series spacecraft
Published 2025-07-01“…To address these issues, this paper proposes a universal ground testing device that integrates remote control and telemetry communication, scientific data transmission, as well as AD (Analog-to-Digital) and OC (Open Collector) signal detection, and DA (Digital-to-Analog) and Open Collector signal output functions through a modular architecture. …”
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1214
Additive Manufacturing for Automotive Radar Sensors Using Copper Inks and Pastes
Published 2025-03-01“…Radar sensors are critical for obstacle detection and navigation, especially for automated driving. …”
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1215
Free radial forearm flap for reconstruction of postoperative defects in combined and complex treatment of patients with locally-advanced squamous cell carcinoma of the oral cavity
Published 2020-04-01“…It allows restoring vital functions of the oral cavity and achieving good aesthetic and functional results.…”
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1216
The role of SFRP1 in human dermal papilla cell growth and its potential molecular mechanisms as a target in regenerative therapy
Published 2025-03-01“…Also, SFRP1 regulates the cell proliferation capacity of IDPCs and reduces their migration functions. The DPCs' living activity, proliferation, and migration function exhibited a negative correlation with the level of SFRP1. …”
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1217
Mapping Landslide Sensitivity Based on Machine Learning: A Case Study in Ankang City, Shaanxi Province, China
Published 2022-01-01“…We evaluate the performance of the model separately by statistical training and test dataset metrics, including sensitivity, specificity, accuracy, kappa, mean absolute error (MSE), root mean square error (RMSE), and area under the receiver operating characteristic curve. The training success rates of LR, SVM, RF, WOA-RF, and GA-RF models are 0.7546, 0.8317, 0.8561, 0.8804, and 0.8957; the testing success rates are 0.7551, 0.8375, 0.8395, 0.8348, and 0.85007. …”
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1218
Joint Survey Processing. III. Compact Oddballs in the COSMOS Field—Little Red Dots and Transients
Published 2025-01-01“…We draw the upper limit of the AGN luminosity function Φ = 1.1 × 10 ^−7 Mpc ^3 mag ^−1 for M _UV = −21 at redshift of 6. …”
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1219
Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours
Published 2025-06-01“…Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. …”
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1220
Mitigating malicious denial of wallet attack using attribute reduction with deep learning approach for serverless computing on next generation applications
Published 2025-05-01“…Abstract Denial of Wallet (DoW) attacks are one kind of cyberattack whose goal is to develop and expand the financial sources of a group by causing extreme costs in their serverless computing or cloud environments. …”
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