Multiscale phytoplankton dynamics in a coastal system of the eastern English Channel: the Boulogne-sur-Mer coastal area by K. Robache, Z. Hubert, C. Gallot, C. Gallot, A. Epinoux, A. P. Louchart, A. P. Louchart, J.-V. Facq, A. Lefebvre, M. Répécaud, V. Cornille, F. Verhaeghe, Y. Audinet, L. Brutier, F. G. Schmitt, L. F. Artigas

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Establishment and characterization of liver‐specific Apoa4‐Cre and Cyp2c11‐Cre rat models in juvenile and adult stages by Wei Dong, Xiang Gao, Feifei Guan, Jirong Pan, Wei Chen, Li Zhang, Lianfeng Zhang

“…No histological alterations were detected in the livers of the Cre rats. Conclusions Liver‐specific Apoa4‐Cre and Cyp2c11‐Cre rats have been established successfully and could be used to study gene knockout, specifically in juvenile and adult liver.…”
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Preparation of nanosized hypoxia-inducible factor 1α inhibitor and its application in reversing chemoresistance in colorectal cancer cells by ZHENG Chuanhao, DAN Ruijue, XI Xi

“…FYC-1 was also successfully prepared. When FYC-1 was interacted with HCT15 cells, FYC-1 could be better taken up by the cells, indicating that the amphiphilic MYC-1 could be better endocytosed into the cells to exert its function. …”
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Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis by Tomoyuki Iwasaki, Naoe Kaneko, Yuki Ito, Hiroyuki Takeda, Tatsuya Sawasaki, Toshio Heike, Kiyoshi Migita, Kazunaga Agematsu, Atsushi Kawakami, Shinnosuke Morikawa, Sho Mokuda, Mie Kurata, Junya Masumoto

“…Notably, the ALPHA signal between Nod2-WT and RICK was increased upon incubation with MDP, but not when incubated with the same concentrations, L-alanine, D-isoglutamic acid, or the MDP-D-isoform. Thus, we successfully developed Nod2-nodosome in a cell-free system reflecting its function in vivo, and it can be useful for screening Nod2-nodosome-targeted therapeutic molecules for BS/EOS and granulomatous inflammatory diseases.…”
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Feasibility of in vivo small animal imaging using a clinical total-body PET/CT system by Julia G. Mannheim, Wenhong Lan, Maurizio Conti, Franziska Siedler, Marcel A. Krueger, Kristina Herfert, Christian la Fougère, Fabian P. Schmidt

“…No substantial position-dependent effects were detected in the phantom or single-mouse scan across the axial FOV. …”
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Pacemaker migration into the peritoneal cavity in children: a case series by Nicole H. Chicoine, Patrick J. Javid, David H. Rothstein, Samuel E. Rice-Townsend, Kimberly J. Riehle, Terrence U. Chun, Sarah L.M. Greenberg

“…In select asymptomatic cases with preserved device function, delayed or elective surgical intervention may be considered.…”
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تقييم تأثير وسائل الاعلام والدعاية على إدراک المستخدمين للعمارة والعمران "دراسة حالة مشروعات الاسکان في مصر"... by محمود سليمان, ولاء زقدان

“…Where the mass media vision of architecture and construction is limited to the notion th athousing projects are merely architectural designs imbedded within investment enterprises, that target profit at the first place, and that such projects are no longer inconsistent compliance with the basic needs of the units users, in terms of: functional spaces, the social or environmental needs, in accordance with the community's cultureand its distinctive characteristics.Consequently, this research sheds light on the influence exercised by the mass media on the society's culture, consciousness, awareness, and perception of the essence ofarchitecture and settlement. …”
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Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity by Yao Zou, Wei Xiao, Dongzhou Liu, Xianyao Li, Lihua Li, Lijuan Peng, Ying Xiong, Haina Gan, Xiang Ren

“…Results UC‐MSCs, UC‐MSCs‐exo, and NOD mouse splenic T cells were successfully cultured and identified. After T cells were co‐cultured with UC‐MSCs and UC‐MSCs‐exo, both IFN‐γ and IL‐6 were decreased while IL‐10, PGE2, and TGF‐β1 were increased in transcriptional and translational levels. …”
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Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors by Chrysoula Mytareli, Vassiliki Kalotychou, Alexandros Lafioniatis, Gregory Kaltsas, George N. Zografos, Athina Markou, Labrini Papanastasiou, Athanasios Fountas, Dimitra Argyro Vasilliadi, Evanthia Kassi, Evanthia Kassi, Marina Mantzourani, Anna Angelousi

“…MiR-22-3p serum levels successfully differentiated patients with Cushing syndrome from those with non-functioning ATs (area under the curve=AUC=0.800, 95% CI: 0.653–0.953, p=0.01) and controls (AUC= 0.800, 95% CI: 0.610–0.990, p=0.02). …”
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Stereotactic body radiotherapy: a new non-invasive way to conduct pulmonary artery denervation by Manzhen Liao, Manzhen Liao, Taoyue Yao, Yonghui Xie, Shelby Kutty, Jinqiao Liu, Wei Peng, Wei Peng, Ting Huang, Huaiyang Chen, Huaiyang Chen, Haoqin Fan, Zhenghui Xiao, Qiming Liu, Yunbin Xiao

“…The rabbit models of acute thromboembolic pulmonary arterial hypertension (ATEPAH) were established by injecting autologous blood clots into the femoral vein. Right ventricular function and hemodynamics were assessed by echocardiography and right heart catheterization. …”
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A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome by Xiaoxiao Wang, Yingxue Liu, Guanghui Yuan, Jingjie Yang, Xiaowen Liu, Shuyuan Chen, Huaiqian Dou, Panpan Lu, Linfang Han, Duan Li, Cuifang Hao

“…ELISA and Co-IP were used to detect the effects of variants on protein secretion and interactions. …”
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The effect of dexmedetomidine on acute kidney injury after elective major abdominal surgery : a retrospective single-center propensity score matched study by Haibei Liu, Rong Luo, Liu Qian, Yujun Zhang, Wensheng Zhang, Juan Tan, Ling Ye

“…Secondary outcomes included intraopertive average urine output, renal function on the first day after surgery, incidence of postoperative dialysis, postoperative intensive care unit (ICU) admission, in-hospital mortality, length of hospital stay, incidence of intraoperative hypotension and bradycardia, and intraoperative use of inotropes and vasopressors. …”
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Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer by Mengdi Zhu, Jinna Lin, Haohan Liu, Jingru Wang, Nianqiu Liu, Yudong Li, Hongna Lai, Qianfeng Shi

“…Conclusions In this study, we successfully constructed a 6-gene acetylation-associated risk model for luminal breast cancer, providing a new direction and evidence for personalized treatment. …”
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Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised... by John Norrie, Stephen Morris, Daniel Francis McAuley, Bronagh Blackwood, Paul Dark, Matt P Wise, Anthony C Gordon, Kalliopi Kydonaki, Timothy Simon Walsh, David Hope, Christopher Weir, Gavin Perkins, Nazir I Lone, Benedict Creagh-Brown, Julia Boyd, Michael Reade, Richard Anthony Parker, Leanne M Aitken, Valerie J Page, Alasdair MacLullich, Cathrine A McKenzie, Alix Macdonald, Annabel Giddings, Lydia Emerson, Robert Glen

“…Post-ICU outcomes include mortality, anxiety and depression, post-traumatic stress, cognitive function and health-related quality of life at 6-month follow-up. …”
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Narva noorte väärtused ja identiteet by Andu Rämmer, Maria Žuravljova, Anne Kivimäe, Maria Anderson

“…Among them are aspirations towards a successful career, independence from parents and good looks. …”
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How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study by Joshua Dissemond, Tim Havers, Steffen Held, Stephan Geisler, Tihomir Kostov, Patrick Diel, Svea Türschmann, Maria K. Parr, Eduard Isenmann

“…M. vastus lateralis and M. vastus intermedius). Liver and kidney function, along with endocrine parameters, were measured via blood samples pre- and post-intervention. …”
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Lung cancer intravasation-on-a-chip: Visualization and machine learning-assisted automatic quantification by Christy Wing Tung Wong, Joyce Zhi Xuen Lee, Anna Jaeschke, Sammi Sze Ying Ng, Kwok Keung Lit, Ho-Ying Wan, Caroline Kniebs, Dai Fei Elmer Ker, Rocky S. Tuan, Anna Blocki

“…When introduced into microvascular networks (MVNs) in microfluidic devices, EMT-IC did not affect MVN stability and physiologically relevant barrier functions.To model lung cancer intravasation on-a-chip, EMT-IC was supplemented into co-cultures of lung tumor micromasses and MVNs. …”
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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…In the present study, we show that replacing ECB balance sheet size with random numbers leads to statistically indistinguishable shock response functions and time series of abnormal monetary policy shocks. …”
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Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway by Qiuhong Jiao, Xiufeng Xu, Longwu Xu, Yuying Wang, Shulan Pang, Jie Hao, Xiaohong Liu, Yudan Zhao, Wanpeng Qi, Limin Qin, Tao Huang, Jingtian Li, Tao Wang

“…Double-labeled immunofluorescence showed eIF3a was mostly co-localized with CD31, this result indicated that the development of MCT-induced PAH was related to the regulation of PAECs function (most likely associated with the change of EndMT in endothelial cells). …”
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Native bacteria from a Mediterranean greenhouse associated to soil health and suppressiveness by Jose Ignacio Marín-Guirao, Miguel de Cara-García

“…Among the 52 ecological pathways detected via FAPROTAX database, nitrogen-related functions showed higher presence at the end of the cropping seasons. …”
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