Precision wings treating skeletal class II in growing patients: a systematic review and meta-analysis by Paulo Mecenas, Renata Travassos da Rosa Moreira Bastos, Nathalia Carolina Fernandes Fagundes, David Normando

“…Abstract Background Skeletal Class II malocclusion, often associated with mandibular deficiency, is commonly treated with functional appliances. Precision Wings are a functional appliance that provides an alternative approach by combining mandibular advancement with dental alignment. …”
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Managing moderate-to-severe paediatric asthma: a scoping review of the efficacy and safety of fluticasone propionate/salmeterol by Sira Nanthapisal, Ana Paula Beltran Moschione Castro, Paulo Marcio Pitrez, Chirag Teli, Abhijith P G

“…Search strategies were developed and refined by authors.Charting methods Selected articles were screened for clinical outcome data (exacerbation reduction, nocturnal awakenings, lung function, symptom control, rescue medication use and safety) and a table of key parameters developed.Results Improvements in asthma outcomes with FP/SAL include reduced risk of asthma-related emergency department visits and hospitalisations, protection against exercise-induced asthma and improvements in measures of lung function. …”
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Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis by Tingting Sun, Yuanyuan Jia, Xiaosheng Dong, Yunlong Chai, Zhenmin Bai, Xiao Hou

“…The objective of this review and meta-analysis is to assess the effectiveness of cupping therapy in patients with CMP.Design Systematic review and meta-analysis.Data sources PubMed, Web of Science, EBSCO, Cochrane Library and CNKI (China National Knowledge Infrastructure) were searched through 20 December 2024.Eligibility criteria for selecting studies We included randomised control trials that compared cupping therapy for patients with CMP on outcomes (ie, pain intensity, functional disability and mental health).Data extraction and synthesis Two independent reviewers used standardised methods to search, screen and code included studies. …”
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Digital Platforms for the Built Environment: A Systematic Review Across Sectors and Scales by Michele Berlato, Leonardo Binni, Dilan Durmus, Chiara Gatto, Letizia Giusti, Alessia Massari, Beatrice Maria Toldo, Stefano Cascone, Claudio Mirarchi

“…Unlike existing reviews focused on single technologies or sectors, this work offers a cross-sectoral synthesis, highlighting shared challenges and opportunities across disciplines and lifecycle stages. It identifies the functional roles, enabling technologies and systemic barriers affecting digital platform adoption, such as fragmented data sources, limited interoperability between systems and siloed organizational processes. …”
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Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains by Yuanyuan Li, Xi Xiang, Zhiyuan Ren, Rui Wang, Minghui Xie, Gen Li, Xiaohui Yan, Zhilong Zhao, Zixin Deng, Min Xu, Anwei Hou

“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of CD34+ Cells by Dorian Forte, Daria Sollazzo, Martina Barone, Marisole Allegri, Angela di Martella Orsi, Marco Romano, Barbara Sinigaglia, Giuseppe Auteri, Nicola Vianelli, Michele Cavo, Francesca Palandri, Lucia Catani

“…Taken together, these data indicate that combined proinflammatory stimuli promote distinct in vitro functional activation of neonatal or adult normal HSPCs.…”
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Ocular Toxicity Associated with Tamoxifen Administration in Patients with Breast Cancer: A Systematic Review by Tejaswi Vadde, Neha Narayan, Amulya Varshini Banka, Shravani Divity, Yethindra Vityala

“…Introduction: Tamoxifen (TAM), a selective Oestrogen Receptor (ER) modulator, is widely used for treating and preventing ER-positive Breast Cancer (BC). …”
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Bertolotti Syndrome: Does it really exist? systematic review by Acevedo-Gonzalez Juan Carlos, Delgado-Caicedo Mónica Gabriela, Lacouture-Silgado Isabella

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Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy by Ping Li, Alice Butler, Yu Zhou, Karl L. Magleby, Christina A. Gurnett, Lawrence Salkoff

“…The Kv3.2 subfamily of voltage activated potassium channels encoded by the KCNC2 gene is abundantly expressed in neurons that fire trains of fast action potentials that are a major source of cortical inhibition. Gain-of-function (GOF) de novo pathogenic variants in KCNC1 and KCNC2, encoding Kv3.1 and Kv3.2 respectively, cause several types of epilepsy including developmental and epileptic encephalopathy (DEE). …”
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Identification and Comprehensive Evaluation of Drought Tolerance in Sorghum During Germination and Seedling Stages by Manhong Wang, Irshad Ahmad, Bin Qin, Lei Chen, Weicheng Bu, Guanglong Zhu, Guisheng Zhou

“…In this study, 19 sorghum varieties from both domestic and international sources were selected as experimental materials. At the seedling stage, 11 above-ground and below-ground phenotypic traits were investigated. …”
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Erythrina lysistemon Hutch. abates deranged metabolic indices linked with diabetic complications in experimental rat model by Kolawole Olofinsan, Veronica Salau, Ochuko Erukainure, Md. Shahidul Islam

“…This study investigated the in vivo activity of E. lysistemon bark extract on animal models of type 2 diabetes (T2D) and complications vis-a-vis the effects on pancreatic functional enzymes and morphology, serum biochemical profile, and hepatic glucose metabolism. …”
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Sport commitment among children and adolescent through the lens of theory of organismic integration: A systematic literature review by Anna Pavlova

“…Since the documents were selected from two scientific databases, duplicate publications were excluded from the output (Pavlova, 2024). …”
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Multi-directional deformation for coordinating isotropy and strength-ductility synergy in a CoCrNi alloy by Na Lin, Zhicheng Miao, Mingcan Li, Rumeng Huang, Kaiyuan Zheng, Zhaowen Huang, Donghui Wen, Cong Zhang, Anding Wang

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Bioactives and Other Nutritional Components in the Jaggery Production Process by Nisha Pujari, Nirali Dedhia, Sanjay Mahajani, Narendra Shah, Amit Arora

“…Jaggery, a non-centrifugal sugar (NCS), is a naturally produced sweetener and a good source of minerals, essential vitamins and bioactives. …”
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A novel acidic laminarinase derived from Jermuk hot spring metagenome by Ani Paloyan, Tigran Soghomonyan, Mariam Karapetyan, Hasmik Grigoryan, Anna Krüger, Fiona Cuskin, Jon Marles-Wright, Christin Burkhardt, Garabed Antranikian

“…Abstract Laminarinase, an enzyme with a specific affinity for laminarin—a complex polysaccharide found in the cell walls of brown algae and select marine organisms—was investigated in this study. …”
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Machine learning prediction of pKa of organic acids by Juda Baikété, Alhadji Malloum, Jeanet Conradie

“…Further molecular descriptors have been generated using density functional theory (DFT) calculations, and RDKit library. …”
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Environmental impact assessment of maize cultivation system considering different irrigation methods by Filippo Vigo, Michele Zoli, Daniela Lovarelli, Jacopo Bacenetti

“…One ton of ear maize silage at 48% moisture content was selected as functional unit and a “from cradle to farm gate” was considered as system boundary . …”
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Exploring interactions between shading and view using visual difference prediction by Stephen Wasilewski, Marilyne Andersen

“…This paper is an exploration of how to approach the characterisation of view clarity through different facades as a function of both the facade and the view itself. While the findings are preliminary, there is already an indication that the type of view content matters to how well people will see through different systems, an important consideration when planning mock-ups and selecting shade fabrics, blinds or electrochromic glazing.…”
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Identification and molecular docking mechanism of novel anti-inflammatory peptides from Lactobacillus paraplantarum fermented Cannabis sativa L. (hemp) seeds by Lingyue Shan, Akanksha Tyagi, Hun Ju Ham, Deog Hwan Oh

“…Overall, these findings indicate that hemp seeds have potential to be a source of bioactive peptides for functional foods with anti-inflammatory properties.…”
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Prevalence of autoimmune thyroid disease in patients with psoriasis: a meta-analysis by Peng Zhang, Ruifang Wu, Xiaochao Zhang, Suhan Zhang, Siying Li, Yuwen Su

“…This meta-analysis aims to determine the association between psoriasis and AITD.Design A meta-analysis of observational studies.Data sources PubMed, EMBASE, Scopus and the Cochrane Library were searched up to 1 November 2021.Eligibility criteria for selecting studies We included non-randomised studies, each with over 50 cases in every group, focusing on the rate of comorbidity between psoriasis and AITD.Data extraction and synthesis Two independent reviewers screened the articles and extracted data. …”
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