Suggested Topics within your search.
Suggested Topics within your search.
-
1821
Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema
Published 2024-01-01“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
Get full text
Article -
1822
KAJIAN PENGETAHUAN LOKAL MASYARAKAT PETANI DALAM PENGELOLAAN DAERAH ALIRAN SUNGAI (DAS) KETAHUN DI KABUPATEN LEBONG
Published 2017-08-01“…An analytical descriptive method is used analyze data gathered from interview to 80 farmers selected by purposive sampling. The reserach indicates that sources of farmers’ local knowledge on natural resources management come from internal and external social system. …”
Get full text
Article -
1823
Dimensional impact of supply chain management on service delivery quality in South African municipalities
Published 2025-05-01“…However, customer relationships, cross-functional teams, strategic sourcing and internal lean practices negatively impacted SCR. …”
Get full text
Article -
1824
Design and Application of Mesoporous Catalysts for Liquid-Phase Furfural Hydrogenation
Published 2025-03-01“…Finally, key challenges that require further investigation are discussed, including catalyst stability, deactivation mechanisms, strategies to reduce reliance on external hydrogen sources, and the impact of solvent effects on product selectivity. …”
Get full text
Article -
1825
De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</...
Published 2024-10-01“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
Get full text
Article -
1826
FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation
Published 2025-05-01“…In this study, FREQ‐NESS is applied to source‐reconstructed magnetoencephalography (MEG) data during resting state and isochronous auditory stimulation. …”
Get full text
Article -
1827
A vehicle coordinate system reconstruction method for end of line calibration applications
Published 2025-07-01“…Then, the method for selecting the necessary feature points and its general applicability are discussed. …”
Get full text
Article -
1828
Antimicrobial peptides and proteins against drug-resistant pathogens
Published 2024-12-01“…These bioactive molecules, whether derived from natural sources, designed synthetically, or predicted using artificial intelligence, can induce lethal effects on pathogens by targeting key microbial structures or functional components, such as cell membranes, cell walls, biofilms, and intracellular components. …”
Get full text
Article -
1829
Nano selenium in broiler feeding: physiological roles and nutritional effects
Published 2024-11-01“…Nutrition of permitted and optimal levels is very important in the consumption of nano selenium form and as it can have significant beneficial functional and health effects, in case of errors in the selected levels and doses, irreparable side effects and adverse results can occur. …”
Get full text
Article -
1830
rangr: An R package for mechanistic, spatially explicit simulation of species range dynamics
Published 2025-03-01“…Several mechanistic, spatially explicit models have been proposed to address this issue, but they do not cover the full range of potential functionalities. We present a new open‐source R package called rangr, which integrates population dynamics and dispersal into a mechanistic virtual species simulator. …”
Get full text
Article -
1831
A novel method for accelerating surgical wound healing in rabbits by collagen extraction from carp (Cyprinus carpio) fish skin
Published 2025-04-01“…The extracted collagen was characterized by low viscosity, transparency, and a watery consistency; the functional groups of collagens were detected using Fourier Transform Infrared Spectroscopy. …”
Get full text
Article -
1832
Risk factors for major low anterior resection syndrome: meta-analysis and systematic literature review
Published 2021-03-01“…Material and Methods — Systematic review and meta-analysis were performed according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The study selected publications that included the functional results of treatment of patients operated for rectal cancer. …”
Get full text
Article -
1833
Temporal Markers as a Way of Modeling the Artistic Space of the Poem “Pe aceeași ulicioară” by M. Eminescu
Published 2023-02-01“…The purpose of the study is to identify the specifics of the temporal structure of the poem “Pe aceeași ulicioară”, taking into account the meaning-forming function of temporal markers in its cognitive scenario, structuring the temporal perspective of the poem and modeling the emotional world of the lyrical hero.Methodology and sources. …”
Get full text
Article -
1834
Repurposing the memory-promoting meclofenoxate hydrochloride as a treatment for Parkinson’s disease through integrative multi-omics analysis
Published 2025-06-01“…MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice. …”
Get full text
Article -
1835
Ecotoxicological evaluation in aquaculture in state park Serra do Mar-SP, Nucleo Itariru
Published 2014-01-01“…We concluded that this fish farm do not represent a source of contamination. Moreover, toxicity tests seem to constitute a tool to evaluate environmental quality in aquaculture.…”
Get full text
Article -
1836
Fast-timing spectroscopy with the ν-ball2 spectrometer
Published 2025-01-01“…In the first stage, the neutron beam was produced by the LICORNE source in an inverse kinematics reaction with a pulsed 7Li beam delivered by the Tandem accelerator, incident on an H2 gas cell. …”
Get full text
Article -
1837
Utilization of Date palm (Phoenix dactylifera L.) wastes for bioethanol production using Pichia kudriavzevii strains
Published 2022-02-01“…Moreover, the Pichia kudriavzevii strains could be recommended for bioethanol production at 30 % inoculum size, on using sucrose as a carbon source and yeast extract as a nitrogen source. On using the Fourier-Transform Infrared (FTI) spectroscopy, the detected functional group of the produced bioethanol was O-H group. …”
Get full text
Article -
1838
Effects of moderate-protein and high-protein diets, including mealworm meal or poultry by-product meal, on immunological variables in healthy adult dogs
Published 2025-08-01“…An interaction effect between the dietary protein source and protein level could be detected for the phagocytic activity of blood granulocytes as well as for the plasma concentrations of IgA and IgE. …”
Get full text
Article -
1839
Characterization of multi-targeted insulin-mimetic antidiabetic peptides using in silico approaches.
Published 2025-01-01“…The aim of the current study was to develop hypoglycemic peptides (HGPs) from plant sources and to investigate their binding interactions with selected diabetic protein receptors using peptide-protein docking, in order to identify potential peptide candidates for the treatment of diabetes mellitus. …”
Get full text
Article -
1840
Wheat crop producers’ technical efficiency and its determinants in Oromia region of Ethiopia: evidence from West Shewa zone
Published 2024-12-01“…The stochastic Cobb-Douglas production function was estimated to measure the level of technical efficiency. …”
Get full text
Article