Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. by Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota

“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
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Experimental Study of Coherent Collaborative Processing Method in Distributed Automotive Radar by A. A. Kuzin, S. E. Kuznetsov, A. V. Miakinkov, R. S. Fadeev, S. A. Shabalin

“…Intelligent driver assistance systems are increasingly employing radar systems to detect, resolve, and track various classes of targets. …”
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Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…Wit, a second Type II receptor, shows a markedly different behavior, with the protein detected on all membrane regions but enriched at the apical side. …”
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Phytochemical Profiling and Antioxidant Activity of True Leaves and Cotyledons of <i>Adenocaulon himalaicum</i> by Sang-Yun Lee, Nari Yoon, Neil Patrick Uy, Chung-Ho Choi, Sanghyun Lee

“…The young leaf of <i>A. himalaicum</i> has a rich phytochemical profile and robust antioxidant activity; hence, it has potential as natural antioxidant sources for human health and valuable pharmacognosy raw materials for pharmaceutical and functional food applications.…”
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Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
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The Role of Rivaroxaban in a Comprehensive Protection Strategy for Patients with Atrial Fibrillation by I. A. Zolotovskaya, V. D. Sabanova, I. L. Davydkin

“…Atrial fibrillation is often asymptomatic and timely detection of these patients can be one of the most important tasks in the complex of measures aimed at protecting patients from stroke. …”
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FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction by Clarissa Tacto, Meghan Tahbaz, Andrew Salib, Shudi Wang, Fritz Cayabyab, Jinhyuk Choi, Kiyoka Kim, Yu Hamba, Harvey Perez, Paul D. Gershon, Robert Damoiseaux, Tae Gyu Oh, Eiji Yoshihara

“…These results suggest that FXYD2 marks and regulates human β cell maturation via channel-sensing signal transduction and that it can be used as a selection marker for functional heterogeneity of stem cell derived human islet organoids.…”
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INFORMATION TECHNOLOGY FOR THE INTEGRATED ASSESSMENT OF EXPERT COMPETENCY by Olena Lobach, Igor Babych, Elena Persiyanova

“…The following results were obtained: the problem of assessing the quality of experts was considered; based on the authors’ practical experience and analysis of literature sources, the structural diagram of the properties of experts and their assessment was developed; five main groups of existing methods for assessing the quality of experts were analyzed; existing models of an integrated assessment of the competency of experts were reviewed; a two-stage method for the integrated assessment of the competency of experts was developed by integrating the methods of heuristic, test, and statistical assessment; the main groups of users and functional requirements to the information system for assessing the competency of experts were identified; the database and user interface of the information system were developed; the developed information technology of the integrated assessment of the competency of experts was tested on actual data for selecting an expert group to choose the methodology of project management. …”
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Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
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Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
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Distance Conversion Factors for In Situ H-Field Emissions Tests by Jordi Sole-Lloveras, Yasutoshi Yoshioka, Manuel Anon-Cancela, Thilo Kootz, Ferran Silva, Marco A. Azpurua

“…An algorithm is developed to extract the H-field strengths normalized to the reference distance and then, through methods for optimal detection of changepoints, such a normalized curve is fitted to a piece-wise linear function that becomes the generalized distance conversion factor, presented in the form of simplified equations. …”
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Biased thalamic innervation onto the distinct subregion where dopamine receptor 1 is dominantly expressed in the caudal striatum by Fuko Kadono, Jingqi Wang, Kenta Kobayashi, Fuyuki Karube, Fumino Fujiyama

“…Retrograde tracer labeling identified potential sources of subcortical glutamatergic projections. …”
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A Systematic Review and Meta-analysis of Scrub Typhus and its Association with Liver Disease by Shalini Balamurugan, Reenaa Mohan, Jenifer Florence Mary, Kulkarni Sweta, Tresa Remya Athipozhi Thomas, Saranya Selvamurthy, Sanjay Pasupathy

“…The studies selected were all scrub typhus patients associated with liver diseases. …”
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Main trends of the international market of educational services by T. I. Chinaeva

“…The largest world sources of the international students are such countries now as: India, China, Korea. …”
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Carbon Dioxide Storage Site Location and Transport Assignment Optimization for Sustainable Maritime Transport by Yanmeng Tao, Ying Yang, Yuquan Du, Shuaian Wang

“…We formulate the problem as a mixed-integer programming (MIP) model and demonstrate that the objective function exhibits submodularity, reflecting diminishing returns in facility investment and ship operations. …”
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Integrating brain proteomes and genetics to identify novel risk genes in chronic widespread musculoskeletal pain by Zhisen Dai, Yanlin Wu, Huaqing Huang, Huizhe Zheng

“…These genes were expressed in pain-related brain regions and showed selective expression in oligodendrocytes, microglia, dopaminergic neurons, and interneurons. …”
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Sunflower-based butterfly optimization algorithm with enhanced RNN for the harmonics elimination in multilevel inverter by V. Mohan, G. Krithiga, M. Thamil Alagan, V. Sathya

“…In a cascaded MLI, the Selective Harmonic Elimination (SHE) and Pulse Width Modulation (PWM) approach is employed to mitigate lower harmonics by maintaining the needed fundamental voltage. …”
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Effects of climate change on goat production and mitigatory measures in semiarid savanna ecosystems by Alban Mugoti, Casper Nyamukanza, Anderson Munengwa, Sizo Moyo, Nation Chikumba

“…Emerging practices such as developing heat-tolerant goat breeds and utilizing drought-resistant forage species through selective breeding programmes and ecological restoration initiatives can be enhanced and adopted. …”
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The Digital Transformation of Tafsir and Its Implications for Islamic Legal Derivation in the Contemporary Era by Ali Sati, Abdul Halim, Abdul Hayy Nasution, Muhammad Ridwan

“…This article explores the impact of selected tools—such as AI-driven tafsir platforms, semantic databases, and multimedia applications—on formulating Islamic legal reasoning in the digital era. …”
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