De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han

“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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In-band network telemetry system based on high-performance packet processing architecture VPP by Tian PAN, Xingchen LIN, Jiao ZHANG, Tao HUANG, Yunjie LIU

“…An in-band network telemetry-based system was built based on VPP, a high-performance virtual network forwarding architecture/device, via reorganizing the data plane pipeline processing modules.Moreover, a network-wide telemetry mechanism was further developed via embedding source routing into the probe packet header for specifying the route of probe packets.Finally, a virtual network topology was built with performance evaluation conducted.The evaluation shows that the telemetry system can monitor the network in a high precision of every 0.13 ms, detecting link congestion in real time with minor performance overhead.Given virtual network devices have been widely deployed in data centers, the proposed scheme is expected to improve the reliability of multi-tenancy and network function virtualization in data centers via high-precision, network-wide virtual link telemetry coverage.…”
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Rapid parameter estimation for merging massive black hole binaries using continuous normalizing flows by Bo Liang, Minghui Du, He Wang, Yuxiang Xu, Chang Liu, Xiaotong Wei, Peng Xu, Li-e Qiang, Ziren Luo

“…Detecting the coalescences of massive black hole binaries (MBHBs) is one of the primary targets for space-based gravitational wave observatories such as laser interferometer space antenna, Taiji, and Tianqin. …”
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Preliminary Study on Natural Infection of Shellfish with Movement Disorder Nodavirus (MDNV) by Ping LI, Jitao XIA, Changming BAI, Ruidong XU, Tingting XU, Shuang LIU, Liang YAO, Xingtong YU, Qingli ZHANG

“…Shellfish is an important source of high-quality protein for human beings and simultaneously plays an important ecological service function in the marine ecosystem. …”
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State immunological reactivity and autonomic regulation in patients with chronic apical periodontitis

“…In this paper we studied 107 people with a diagnosis of «chronic apical periodontitis». The functional state of the autonomic nervous system were detected by electrophoresis dosed adrenaline and carbachol and test dermographism. …”
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JWST/NIRCam Narrowband Survey of Paβ Emitters in the Spiderweb Protocluster at z = 2.16 by Rhythm Shimakawa, J. M. Pérez-Martínez, Helmut Dannerbauer, Yusei Koyama, Tadayuki Kodama, Pablo G. Pérez-González, Chiara D’Eugenio, Yuheng Zhang, Abdurrahman Naufal, Kazuki Daikuhara

“…The weight-corrected color–magnitude diagram obtained 57 sources showing narrowband excesses, 41 of which satisfy further color selection criteria for limiting the sample to Pa β emitter candidates at z ∼ 2.16, and 24 of them do not have H α emitter counterparts. …”
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Unveiling the complex double-edged sword role of exosomes in nasopharyngeal carcinoma by Xueyan Huang, Yuedi Tang

“…Exosomes are small membrane vesicles at the nanoscale that transport physiologically active compounds from their source cell and have a crucial function in signal transmission and intercellular message exchange. …”
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Face Recognition Door Security System and Contactless Bell by Rini Irnayanti, Elfizon Elfizon

“…Face recognition uses OpenCV based on an open source library to recognize faces in realtime using the Python programming language.  …”
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Reconstruction of defects in elastic bodies by combination of genetic algorithm and finite element method by Arkady N Solovyev, Mikhail Y. Shevtsov

“…The inverse problem solution is based on the minimization of the residual functional between the measured input source information and the data calculated during the numerical solution of direct problems with the given parameters of defects. …”
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Synthesis and Production of Sweet-Tasting Protein in E. coli and Purification by Amylose Resin by F. Mansouri

“…However, the extraction of brazzein from its natural source is expensive and not applicable. In this study we used recombinant DNA technology to provide an alternative option for cheaper mass production of brazzein. …”
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PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm by Naeem Shirmohammady, Habib Izadkhah, Ayaz Isazadeh

“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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A lightweight transformer based multi task learning model with dynamic weight allocation for improved vulnerability prediction by Lan Liu, Zhanfa Hui, Guiming Chen, Tingfeng Cai, Chiyu Zhou

“…Traditional methods, such as single-task learning and ensemble approaches, often struggle with these challenges, particularly in detecting rare but critical vulnerabilities. To address this, we propose the MTLPT: Multi-Task Learning with Position Encoding and Lightweight Transformer for Vulnerability Prediction, a novel multi-task learning framework that leverages custom lightweight Transformer blocks and position encoding layers to effectively capture long-range dependencies and complex patterns in source code. …”
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IRRADIATION EFFECT ON PEROXIDATION INDEX ON OKARABASED SOYBEAN FLOUR by Ana Paula Nunes

“…We conclude that this product with excellent nutritional attributes about the commercial flour, we must apply a different methodology to detect any radiation damage on lipid compounds.…”
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Bioactive components derived from bovine milk by Katarina Lisak Jakopović, Irena Barukčić, Rajka Božanić

“…In recent years, functional foods and bioactive components in foods have drawn a lot of attention as well as interest of food scientists, nutritionists, health professionals, and consumers. …”
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Fast-timing spectroscopy with the ν-ball2 spectrometer by Pascu S., Hiver C., Podolyák Zs., Regan P.H., von Tresckow M., Wilson J.N.

“…In the first stage, the neutron beam was produced by the LICORNE source in an inverse kinematics reaction with a pulsed 7Li beam delivered by the Tandem accelerator, incident on an H2 gas cell. …”
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Canopy Chlorophyll Content Inversion of Mountainous Heterogeneous Grasslands Based on the Synergy of Ground Hyperspectral and Sentinel-2 Data: A New Vegetation Index Approach by Yi Zheng, Yao Wang, Tayir Aziz, Ali Mamtimin, Yang Li, Yan Liu

“…This study confirms that the synergistic use of multi-source data effectively overcomes the limitations of the spectral–spatial resolution of a single data source, providing a novel methodology for the precision monitoring of mountain ecosystems.…”
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Comparing soil microbial diversity in smallholder plantain backyard gardens and main farms in Western and Central Africa by Manoj Kaushal, Yao Adjiguita Kolombia, Amos Emitati Alakonya, Cargele Masso

“…Beneficial genera such as Bacillus, Streptomyces, Bradyrhizobium, and Paenibacillus were also detected. Functional predictions based on COG and KEGG databases indicated notable differences in microbial functional potential between the two settings. …”
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