Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
Get full text

Bifidobacterium animalis subsp. lactis genome resources and metabolite profiling at the strain level and their ability to alleviate anxiety-like behavior in a sleep-deprived mouse... by Yao-Kun Zhang, Liang Zhang, Xue Ni, Shu-Wen Zhang, Min-Zhi Jiang, Si-Lu Zhang, Guo-Xun Xiao, He Jiang, Ming-Xia Bi, Yu-Lin Wang, Chang Liu, Shuang-Jiang Liu

“…In this study, we characterized 16 B animalis subsp. lactis isolates from fecal samples and probiotic sources. We assessed the genotype-phenotype correlations related to growth, carbon source utilization, and stress tolerance in vitro. …”
Get full text

SWIPT-Enabled Cooperative Wireless IoT Networks With Friendly Jammer and Eavesdropper: Outage and Intercept Probability Analysis by Dinh Tung Vo, Trinh Van Chien, Tan N. Nguyen, Dinh-Hieu Tran, Miroslav Voznak, Byung Seo Kim, Lam Thanh Tu

“…In this context, a low-complexity, sub-optimal, but efficient relay selection method is proposed. More specifically, the relay is selected to convey information such that it has the best channel to the source. …”
Get full text

Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
Get full text

Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

Get full text

Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
Get full text

Iodine deficiency as an environmental risk factor for thyroid gland diseases in animals by І. P. Ligomina, I. M. Sokulskyi, V. M. Sokolyuk, B. V. Gutyj, L. M. Soloviova

“…The situation is complicated in the biogeochemical zones of Ukraine, where insufficient or excessive content of mobile forms of microelements in soils and water sources determines the biological reaction of local flora and fauna. …”
Get full text

Environmental sustainability of cotton: a systematic literature review of life cycle assessments by Giuseppe Salvatore Vitale, Nicolò Iacuzzi, Silvia Zingale, Sara Lombardo, Teresa Tuttolomondo, Paolo Guarnaccia

“…This review analyzes twenty peer-reviewed studies on cotton life cycle assessments, selected from Scopus and Web of Science according to PRISMA guidelines and covering the period 2010–2022. …”
Get full text

Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…First, in order to form the theoretical foundations of the research, an comprehensive search was conducted among articles, books, researches, reports and other reliable scientific sources. Then, the topic in question was examined in relation to the selected countries (based on the 2022 Global Innovation Index report) in order to provide a basis for a comparative study and comparison of Iran's situation with the mentioned countries. …”
Get full text

Identifying potential nutrient acquisition mechanisms for long-term survival: adaptive evolution of Halomonas isolated from subseafloor crustal fluids by Hans Sebastian, Alberto Robador, Dawson Ray, Angus Angermeyer, Steven D’Hondt, Julie A. Huber, Steven E. Finkel

“…The application of an adaptive evolution platform selecting for survival and growth under one environmental condition that simultaneously selects against survival in different environments may prove to be a very useful tool for identifying genes and metabolic pathways in a wide variety of complex environments.…”
Get full text

Insight into influence of degradation metabolism of Firmicutes on the microstructure of anthracite coal by Yuewu Wang, Bingjun Liu, Sheng Xue, Yang Yang, Jian Chen, Jingbei Zhang, Chunshan Zheng, Tianyao Zhou

“…Fourier Transform Infrared Spectrometer (FTIR) experiments revealed that biodegradation stimulated by nitrogen source reduced the aromaticity of coal by 59.62% and enhanced the hydroxyl functional group content by 1.822 times. …”
Get full text

GRAPHIC NOVEL TRANSLATION: SEMIOTIC AND MULTIMODAL PERSPECTIVE by Anna V. Khodorenko.

“…On the one hand, extralinguistic objects engraved in pictures of the graphic novel may present the reason for the translation technique of addition, and on the other hand the absence of some details in the pictures may justify the translation technique of omission. Evaluating functional types of multimodal phenomena also may lead one to adequate selection of synonyms or a phrase to choose in a process of translation having as a “guide” visual image supporting language level of a graphic novel. …”
Get full text

Metallosphaera sedula bifurcates into two sizes when it is cultured mixotrophically on soluble iron by Robert C. Blake, Richard G. Painter, Nghi Pham, Olivia Griswold, Brooke White, Richard A. White, Richard A. White, Richard A. White

“…Metallosphaera sedula is a thermoacidophilic archaeon that obtains all of its energy for growth from aerobic respiration and oxidative phosphorylation at the expense of selected organic and inorganic sources of electrons. …”
Get full text

Framework for early assessment of food safety hazards in the transition to a more sustainable food system: three case studies in the Vietnamese Mekong Delta by Rosa A. Safitri, Lianne M.S. Bouwman, Marianna Siegmund-Schultze, Tri Minh Nhan, Mohammed Ariful Islam, Esther D. van Asselt, Katja C.W. van Dongen

“…This study applied a qualitative framework to investigate changes in the occurrence of food safety hazards resulting from adopting adaptation strategies at primary production. We selected three case studies (CS) in the VMD: (1) adaptation in the usage and application of water sources for agricultural production, (2) shifting from monoculture rice, duck, and fish to an integrated crop-livestock farming, and (3) introduction of a new crop (i.e., quinoa). …”
Get full text

First De Novo genome assembly and characterization of Gaultheria prostrata by Yan-Jun Lin, Xiao-Ya Ding, Yi-Wei Huang, Yi-Wei Huang, Lu Lu

“…(Ericaceae), a type of evergreen shrub, known as a natural source of methyl salicylate, possesses rich germplasm resources, strong habitat adaptability, significant ornamental value, and noteworthy pharmacological activities. …”
Get full text

Automated Recipe Generation AI Tool from Food Images using Machine Learning. Approach for Ingredient Extraction and Cooking Instructions by Lwamaza, Eddy, Nuwasiima, Happy

“…It outlines the systematic approach taken to analyze user needs, define functional and non-functional requirements, and develop a robust system architecture. …”
Get full text

Pollution Risk Assessment of Potentially Toxic Elements in Soils Using Characterization and Microbiological Analysis: The Case of a Rare and Precious Metal Mining Site in Wuzhou, G... by Yi Sun, Zixuan Yang, Kun Dong, Fujiang Hui, Dunqiu Wang, Yecheng Huang

“…The Probability Mass Function (PMF) model was used to perform a source apportionment of the PTEs and determine the main pollution sources and their contribution rates. …”
Get full text

Need to clamp indwelling urinary catheters before removal after different durations: a systematic review and meta-analysis by Xiaoyan Fan, Sumin Ma, Jiayi Gu

“…Objective This meta-analysis aimed to evaluate the effect of bladder training by clamping on bladder urethral function in patients with indwelling urinary catheters used for different durations.Design Systematic review and meta-analysis.Data sources The UpToDate, Cochrane Library, OVID, PubMed, China National Knowledge Infrastructure, CINAHL and Embase were screened from 1 January 2000 to 28 February 2022.Eligibility criteria for selecting studies Randomised controlled trials (RCTs) or quasi-experimental designs comparing the efficacy of bladder training in patients with an indwelling urinary catheter by clamping or free drainage before urinary catheter removal were published in English or Chinese.Data extraction and synthesis Two reviewers independently extracted the data and assessed the quality of studies. …”
Get full text

A comparative assessment of WASH adherence among public and private school students in a rural district in Nigeria by Ayoola O. Bosede, Rejoice C. Enwenonu, Justina U. Udensi, Onyenonachi C. Ihejirika, Kolawole C. Akindulureni, Onyima C. Emenonu, Thelma C. Mezieobi

“…A multi-stage sampling technique was used to select 20 secondary schools, with a total of 400 students participating in the study. …”
Get full text

Expressing the Author's Position in the English-Language Network Film Review by I. V. Kononova, T. A. Klepikova, E. A. Klenova

“…The authors proceed from the position that the methods of subject verbalization are determined by functional characteristics of discourse. The relevance of the study is due to the interest of modern linguistics in the study of the subject factor in “personal” types of discourse. …”
Get full text