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The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021
Published 2025-06-01Get full text
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1303
A novel deep learning technique for multi classify Alzheimer disease: hyperparameter optimization technique
Published 2025-04-01“…A progressive brain disease that affects memory and cognitive function is Alzheimer’s disease (AD). To put therapies in place that potentially slow the progression of AD, early diagnosis and detection are essential. …”
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1304
Risks as an object of internal control: identification and assessment
Published 2021-08-01“…The main purpose of internal control is to ensure timely detection and analysis of business risk, reliability of relevant information, integrity of assets, compliance with regulations, internal policies and procedures, implementation of plans and efficient use of resources. …”
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1305
Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di...
Published 2020-03-01“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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1306
BIOINFORMATICS — INSTRUMENT INTERPRETATION PROTEOMIC PROFILES OF MEAT PROTEIN
Published 2017-04-01“…Studies in this field have enabled formulating and significantly expanding the approaches to the identification and quantification of protein markers of quality, functionality and safety of meat raw material (detection of falsification) in the finished meat products. …”
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1307
Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment
Published 2025-06-01“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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1308
Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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Intranasal administration of stem cell derivatives for the treatment of AD animal models: a systematic review and meta-analysis
Published 2025-07-01“…Subgroup analyses indicated that stem cell source, stem cell derivative types and Aβ detection method were not primary drivers of heterogeneity. …”
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1310
Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake
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1311
Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region
Published 2025-01-01“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
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1312
Conditions for the emergence of circumnutations in plant roots.
Published 2021-01-01“…Here we describe a model capable of replicating root growth behaviors, which we used to analyze the role of circumnuntations, revealing their emergence I) under gravitropic stress, as a combination of signal propagation and sensitivity to the signal carriers; II) as a result of the interplay between gravitropic and thigmotropic responses; and III) as a behavioral strategy to detect and react to resource gradients. The latter function requires the presence of a hypothetical internal oscillator whose parameters are regulated by the perception of environmental resources.…”
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Chromosome-level genome assembly of starry flounder (Platichthys stellatus)
Published 2025-07-01“…Approximately 94.02% of assembled sequences were anchored into 24 pseudochromosomes, and a total of 18 telomeres were detected. Totally 22,835 protein-coding genes and 227.87 Mb repetitive sequences were identified. …”
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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons
Published 2025-07-01“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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Identification method of roof rock interface based on response characteristics of drilling parameters
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1316
Epidemic preparedness and response capacity against infectious disease outbreaks in 186 countries, 2018–2022
Published 2024-11-01“…From the 2022 submissions, 116 (62%) countries reported functional (Level 4 or 5) prevention capacity, 162 (87%) had functional detection capacity, 118 (63%) had functional response capacity, 121 (65%) had functional enabling resources and coordination capacity, and 133 (72%) had functional operational readiness against public health events. …”
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Study of Complex Impedance Dispersion Model for Two-Phase Laminar Flow
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1318
Unravelling the Impact of an Additional Sex Chromosome in an Adult Female
Published 2023-04-01“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
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IGFBP7 promotes the proliferation and differentiation of primary myoblasts and intramuscular preadipocytes in chicken
Published 2024-12-01“…We then examined the expression patterns of IGFBP7 across different stages of proliferation and differentiation in CPMs and intramuscular preadipocytes via qPCR, and explored the biological functions of IGFBP7 through gain- and loss-of-function experiments and a range of techniques including qPCR, CCK-8, EdU, flow cytometry, Western blot, immunofluorescence, and Oil Red O staining to detect the proliferation, differentiation, and lipid deposition in CPMs and intramuscular preadipocytes. …”
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1320
On path length, beam divergence, and retroreflector array size in open-path FTIR spectroscopy
Published 2025-06-01“…<p>Open-path Fourier transform infrared (OP-FTIR) spectroscopy is an established technique used to measure boundary layer trace gas concentrations, consisting (in this work) of a spectrometer with an active mid-IR source coupled to a single transmitting and receiving telescope, as well as a cube-corner retroreflector array separated from the spectrometer and telescope by an atmospheric path. …”
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