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441
Myoglobin expression improves T-cell metabolism and antitumor effector function
Published 2025-06-01“…Although T cells expressing Mb exhibited increased expression of effector cytokines, PD-1 was still detected and targetable by anti-PD-1 monoclonal antibodies, which in combination with transfer of Mb-expressing T cells demonstrated maximal efficacy in delaying tumor growth.Conclusion Taken together, we show that expression of Mb in T cells can increase their metabolism, infiltration into the tumor tissue, and effector function against cancer cells.…”
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442
Today’s Mechanisms of Financing the 4th Energy-Transition
Published 2024-05-01“…Current trends of sustainable development define priorities and new approaches to sources and forms of financing. Serious impact on selection of finance mechanisms is made by sectoral specific features demonstrating key lines of development. …”
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443
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444
Harnessing polydiacetylene (PDA): A review of structural mechanics and infectious disease detection
Published 2025-07-01“…These biosensors can also be functionalized with particular capture agents, such as antibodies or nucleic acid probes, to selectively bind and detect the target analytes. …”
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445
Multi task detection method for operating status of belt conveyor based on DR-YOLOM
Published 2025-06-01“…Secondly, as the model requires target recognition and segmentation of different types of tasks, an efficient layer aggregation network (RepGFPN) with skip layer connection structure is adopted to optimize the feature fusion part, greatly improving the detection accuracy of the model for different detection tasks while controlling the number of model parameters and inference speed; Finally, to address the detection tasks of three different label shapes, the Inner CIOU loss function is introduced to compensate for the weak generalization ability of the CIoU loss function in different detection tasks. …”
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446
Highly Efficient Biphoton Generation from Thin Dense Atomic Ensemble
Published 2025-04-01“…Strongly correlated bright biphotons are generated via spontaneous four‐wave mixing from a dense atomic ensemble based on the 6S1/2–6P3/2–6D5/2 transition of 133Cs. Biphoton source achieves a detected biphoton count rate of 100 kilo‐counts per second, a heralding efficiency of 15%, and a maximum normalized crosscorrelation function value of 100 between the signal and idler photons, despite the low detector efficiency of a silicon avalanche photodetector being less than 25% at 917 nm. …”
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447
Ti3C2Tx@Pt nanocomposite based colorimetric and electrochemical dual-mode platform for glucose detection
Published 2025-06-01“…Glucose is the main source of energy in cellular metabolism and is essential for normal cellular function and growth. …”
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448
ChiMSource improves the accuracy of studies on novel amino acid sequences by predicting alternative sources of mass spectrometry-derived peptides
Published 2025-01-01“…Here, we present a highly flexible program that predicts alternative chimeric and non-chimeric sources of peptides detected by MS proteomics.…”
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449
An optimization method of multiscale storage tank target detection introducing an attention mechanism
Published 2024-01-01“…As containers for chemical storage, storage tanks are potential sources of hazards. Conducting target detection for hazard risk analysis is essential. …”
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450
Research on Underwater Target Detection Technology Based on SMV-YOLOv11n
Published 2025-01-01“…High-precision underwater object detection is a crucial component for improving the efficiency of marine resource development. …”
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451
YOLOX-LS: Strong Gravitational Lenses Detection in the DECaLS with Deep Learning
Published 2025-01-01“…We apply the YOLOX algorithm as the basic framework and improve it by selecting the optimal optimizer, activation function, attention mechanism, and loss function. …”
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452
A New Modeling Method for Meteorological Information of Regional Distributed Photovoltaic Power Generation Based on Multi‐Source Information Fusion
Published 2025-08-01“…Precise meteorological information is the foundation for achieving these functions. However, DPV sites are typically scattered with small installed capacities and generally lack dedicated weather stations. …”
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453
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.
Published 2011-09-01“…Two of the three hit regions lie within haplotype blocks (at 2p13.1 and 10q24.2) that carry the genetic signature of strong, recent, positive selection in European populations. Genes NAT8 and PYROXD2, both with relatively uncharacterized functional roles, are good candidates for mediating the corresponding mQTL associations. …”
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454
Metal and metal oxide nanomaterials for heavy metal remediation: novel approaches for selective, regenerative, and scalable water treatment
Published 2024-10-01“…The review identifies several promising nanomaterials, such as graphene oxide, carbon nanotubes, and metal-organic frameworks, which exhibit high surface areas, tunable surface chemistries, and excellent adsorption capacities. Surface functionalization with specific functional groups (e.g., carboxyl, amino, thiol) significantly enhances the selectivity for target heavy metal ions. …”
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455
Object detection with afordable robustness for UAV aerial imagery: model and providing method
Published 2024-08-01“…The model and method for ensuring the robustness of resource-constrained neural network systems for object detection in aerial video surveillance. …”
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456
Source-load coordinated optimal scheduling strategy considering solar thermal biomass utilization under integrated demand response incentives
Published 2024-11-01“…Secondly, on the load side, both price-based and substitution-based demand responses are introduced to improve the low-carbon performance of the IES through source-load coordinated optimization. Then, a liquid storage carbon capture system and a tiered carbon tax mechanism are introduced in the IES to enhance the system's low-carbon economic benefits, establishing an objective function to maximize the system's total revenue. …”
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457
Effect and mode of action of different doses and sources of zinc in weaning pigs using a meta-analytical and systematic review approach
Published 2024-12-01“…A total of 309 articles were identified from a literature research from 2001 to 2021; 85 were selected. Articles were divided in 3 datasets to evaluate: 1) the effects of ZnO doses (ZnO database); 2) the efficacy of ZnO on infection models (challenge database); 3) the effect of different Zn sources (special Zn database). …”
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458
Enterococcus faecalis strains derived from wild bird provide protection against Clostridium perfringens challenge in locally-sourced broilers
Published 2025-05-01“…IntroductionNecrotic enteritis (NE), caused by Clostridium perfringens, has seen a surge in chicken populations recently due to the ban on antibiotic growth promoters in feed.MethodsIn this research, screening and identification of probiotics with strong antagonistic ability against C. perfringens from 34 wild bird fecal isolates, followed by analysis of probiotic characteristics and carbon source metabolic activity. Strains exhibiting favorable antagonistic activity against C. perfringens were subsequently employed in vivo study to evaluate their protective efficacy against C. perfringens challenge in locally-sourced broilers.ResultsThe results showed that Enterococcus faecalis strains YL-EF25 and YL-EF32 were selected based on their ability to inhibit the growth and biofilm formation of C. perfringens. …”
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459
Optimizing Hyperspectral Desertification Monitoring Through Metaheuristic-Enhanced Wavelet Packet Noise Reduction and Feature Band Selection
Published 2025-07-01“…We applied Particle Swarm Optimization (PSO) to fine-tune the Wavelet Packet (WP) decomposition levels, thresholds, and wavelet basis function, ensuring optimal spectral decomposition and reconstruction. …”
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460
Pisum sativum L. as an alternative protein and starch source in Italian Mediterranean buffaloes’ feeding plan: in vitro evaluation of different varieties
Published 2025-12-01“…After multivariate cluster analysis, Ganster, Poisedon and Peps were selected for the second trial in function of highest organic and protein degradability. …”
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