Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

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Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples by Chioma Lilian Ozoaduche, Balázs Libisch, Daniel Itoro, Iyore Blessing Idemudia, Katalin Posta, Ferenc Olasz

“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction by A. V. Pikuza, A. M. Zakirov

“…The focus of purulent inflammation in the abdominal cavity serves as a source of concentration of antimicrobial mechanisms, among which the central role is played by neutrophilic granulocytes and factors cooperating with them. …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves&rsquo; Disease and Graves&rsquo; Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis by Reza Hashemi, Mohammad M. Hussein M. Raouf, Tanya S. Salih, Marzieh Feyzpour, Maryam Eskandarioun, Najmeh Nezamabadipour, Hossein Gandomkar

“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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An Underground Goaf Locating Framework Based on D-InSAR with Three Different Prior Geological Information Conditions by Kewei Zhang, Yunjia Wang, Feng Zhao, Zhanguo Ma, Guangqian Zou, Teng Wang, Nianbin Zhang, Wenqi Huo, Xinpeng Diao, Dawei Zhou, Zhongwei Shen

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Isolation and Characterization of L-Asparaginase-Producing Bacteria from the Arabian–Persian Gulf Region: First Report on <i>Bacillus xiamenensis</i> ASP-J1-4 as a Producer and Its... by Ghofran M. Al-Harbi, Essam Kotb, Abeer A. Almiman, Mahmoud M. Berekaa, Salwa Alhamad, Nada F. Alahmady, Meneerah A. Aljafary, Nadiyah M. Alqazlan, Reem I. Alyami, Joud M. Alqarni, Ebtesam Abdullah Al-Suhaimi

“…L-asparaginase (L-ASNase) functions as a chemotherapeutic enzyme with antitumor properties. …”
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Multimodal AI and Large Language Models for Orthopantomography Radiology Report Generation and Q&A by Chirath Dasanayaka, Kanishka Dandeniya, Maheshi B. Dissanayake, Chandira Gunasena, Ruwan Jayasinghe

“…In addition, the proposed solution includes a question-answering platform in the native Sinhala language, alongside the English language, designed to function as a chatbot for dental-related queries. We hope that this platform will eventually bridge the gap between dental services and patients, created due to a lack of human resources. …”
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Chromosome-scale genome assembly and annotation of two geographically distinct strains of malaria vector Anopheles albimanus by Dieunel Derilus, Gareth D. Weedall, Michael W. Vandewege, Dhwani Batra, Mili Sheth, Lori A. Rowe, Ananias A. Escalante, Audrey Lenhart, Lucy Mackenzie Impoinvil

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Multifaceted roles of Galectins: from carbohydrate binding to targeted cancer therapy by Nan Zhang, Qiao Liu, Daihan Wang, Xiaoyun Wang, Zhaoping Pan, Bo Han, Gu He

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Two-Stage Detectors with Multiple Energy Detectors and Adaptive Double Threshold in Cognitive Radio Networks by Ashish Bagwari, Geetam Singh Tomar

“…Cognitive radio (CR) is a regulated technique for opportunistic access of idle resources. In CR, spectrum sensing is one of the key functionalities. …”
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Multimessenger Signatures of a Deformed Magnetar in Gamma-Ray Bursts by Parisa Hashemi, Soroush Shakeri, Yu Wang, Liang Li, Rahim Moradi

“…We study the evolution of a newly formed magnetized neutron star (NS) as a power source of gamma-ray bursts (GRBs) in the light of both gravitational-wave (GW) and electromagnetic (EM) radiation. …”
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Application of Deep Dictionary Learning and Predefined Filters for Classification of Retinal Optical Coherence Tomography Images by Fariba Shaker, Zahra Baharlouei, Gerlind Plonka, Hossein Rabbani

“…In recent years, deep learning methods have excelled in Optical Coherence Tomography (OCT) image classification but demand high computational resources and extensive training data. We propose two effective methods for OCT image classification, combining the strength of deep learning with sparse representation of significant image features for improved detection of retinal abnormalities. …”
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Identification of miRnas with possible prognostic roles for HAM/TSP by Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Youko Nukui, Juliana Pereira, Rosa Nascimento Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

“…The seven most deregulated miRs target genes have been associated with a variety of biological processes and molecular functions. The reactome pathways relevant to our findings provide a rich source of data and offer the opportunity to better understand sRNA regulation and function in HTLV-1 pathophysiology. …”
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CoreTIA: a modular, statistically robust transduction inhibition assay for AAV neutralization by Beatrix Kovács, Beatrix Kovács, Beatrix Kovács, Fanni Somogyi, Fanni Somogyi, Viktória Szabó, Zoltán Zsolt Nagy, István Hernádi, Ferenc Mátyás, Wim Vanduffel, Zsuzsanna Szemlaky, Balázs Rózsa, Balázs Rózsa, István Ulbert, István Ulbert, István Ulbert, István Ulbert, Dániel Hillier, Dániel Hillier, Dániel Hillier

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Epidemiology of Disability of Adult Population in the Russian Federation by S. N. Puzin, M. A. Shurgaya, N. V. Dmitrieva, G. E. Pogosyan, I. V. Lyalina, A. M. Mammaraeva, T. A. Ivanova, L. S. Idrisova

“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
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Enhanced Efficiency in SMEs Attendance Monitoring: Low Cost Artificial Intelligence Facial Recognition Mobile Application by Hong-Danh Thai, Yeong-Seok Seo, Jun-Ho Huh

“…Applying advanced technologies in human resources can enable organizations to address these challenges effectively. …”
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The Dysregulation of Tuning Receptors and Transcription Factors in the Antennae of <i>Orco</i> and <i>Ir8a</i> Mutants in <i>Aedes aegypti</i> Suggests a Chemoreceptor Regulatory M... by Matthew M. Cooke, Michael S. Chembars, Ronald Jason Pitts

“…Individual tuning receptors in both families require co-receptors for functionality: <i>Orco</i> for all <i>Ors</i>, and <i>Ir8a</i> for many <i>Irs</i>, especially ones that are involved in carboxylic acid detection. …”
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Factors associated with contrast-associated acute kidney injury in an emergency department: A cohort study in Lebanon. by Moustafa Al Hariri, Sally Al Hassan, Malak Khalifeh, Hani Tamim, Imad El Majzoub, Tharwat El Zahran

“…<h4>Background</h4>Contrast-associated acute kidney injury (CA-AKI) is a common problem in hospitals, particularly in low-middle-income countries (LMIC), due to limited resources and a high prevalence of comorbidities. Kidney function evaluation using serum creatinine levels before contrast administration leads to increased length of stay and delayed patient care. …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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