Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability. by Hemant Bengani, Detelina Grozeva, Lambert Moyon, Shipra Bhatia, Susana R Louros, Jilly Hope, Adam Jackson, James G Prendergast, Liusaidh J Owen, Magali Naville, Jacqueline Rainger, Graeme Grimes, Mihail Halachev, Laura C Murphy, Olivera Spasic-Boskovic, Veronica van Heyningen, Peter Kind, Catherine M Abbott, Emily Osterweil, F Lucy Raymond, Hugues Roest Crollius, David R FitzPatrick

“…Assigning causative status to any ultra-rare CRE variant remains problematic and requires disease-relevant in vivo functional data from multiple sources. The sequential and bespoke nature of such analyses renders them time-consuming and challenging to scale for routine clinical use.…”
Get full text

Anisotropic Diffusion of e± in Pulsar Halos over Multiple Coherence of Magnetic Fields by Kai Yan, Sha Wu, Ruo-Yu Liu

“…Also, the halo’s morphology may appear less asymmetric, especially after being smoothed by the point-spread function of instruments. This largely relaxes the tension between the asymmetric morphology of halos predicted by the model and the lack of apparent asymmetric halos detected so far. …”
Get full text

A Decision Support System for Optimal Building Cold Source Selection by Qing Li, Yan Dong, Rong-Guang Cao, Le Li, Zhi-Bin Chen

“…Based on existing approaches to construction project evaluation and the selection of cold source systems, we establish an evaluation index for building cold source system functional models and network structures. …”
Get full text

pyAudioAnalysis: An Open-Source Python Library for Audio Signal Analysis. by Theodoros Giannakopoulos

“…Here we present the theoretical background behind the wide range of the implemented methodologies, along with evaluation metrics for some of the methods. pyAudioAnalysis has been already used in several audio analysis research applications: smart-home functionalities through audio event detection, speech emotion recognition, depression classification based on audio-visual features, music segmentation, multimodal content-based movie recommendation and health applications (e.g. monitoring eating habits). …”
Get full text

Source-detector effective solid angle calculation using MCNP6 code by Roos Sophia de Freitas Dam, Alessandra Galvão Menezes dos Santos, William Luna Salgado, César Marques Salgado

“…In order to use these nuclear techniques is necessary to perform studies of important parameters of radioactive source and radiation detectors, which are part of the measurement geometry, such as detection efficiency and solid angle. …”
Get full text

Immature Skeletal Myotubes Are an Effective Source for Improving the Terminal Differentiation of Skeletal Muscle by Seung Yeon Jeong, Jun Hee Choi, Paul D. Allen, Eun Hui Lee

“…These results suggest that in vitro-cultured D2-to-D3 co-differentiated mature myotubes could be a good alternative source of satellite cells or cultured myoblasts for skeletal muscle regeneration.…”
Get full text

Decoding methane concentration in Alberta oil sands: A machine learning exploration by Liubov Sysoeva, Ilhem Bouderbala, Miles H. Kent, Esha Saha, B.A. Zambrano-Luna, Russell Milne, Hao Wang

Get full text

Multi-View Cluster Structure Guided One-Class BLS-Autoencoder for Intrusion Detection by Qifan Yang, Yu-Ang Chen, Yifan Shi

“…Multi-view OCC approaches usually require collecting multi-view traffic data from all sources and have difficulty detecting intrusion independently in each view. …”
Get full text

Innovation as a Source of Ensuring the Sustainable Development of the Enterprise by Brahina Olha S.

“…The author determines the factors of importance of innovative development in the context of sustainable development and the main functions it performs. The stages of innovative development in the context of sustainable development of enterprise are formed, among which it is worth highlighting the following: analysis and assessment of the current state of enterprise; generation and selection of ideas; development of an innovation strategy; implementation of innovative solutions, monitoring and evaluation of efficiency, adjustment and improvement of strategy, communication of results and involvement of stakeholders. …”
Get full text

An open-source tool for analysis and automatic identification of dendritic spines using machine learning. by Michael S Smirnov, Tavita R Garrett, Ryohei Yasuda

“…Our algorithm is rapid, flexible, has over 90% accuracy in spine detection, and bundled with our user-friendly, open-source, MATLAB-based software package for spine analysis.…”
Get full text

Molecular signature of selective microRNAs in Cyprinus carpio (Linnaeus 1758):a computational approach by Soumendu Ghosh, Manojit Bhattacharya, Avijit Kar, Basanta Kumar Das, Bidhan Chandra Patra

“…Using web based tools total 10 selected miRNAs belongs to 10 different families were illustrated and functionally categorized in Cyprinus carpio. …”
Get full text

An Attomolar-Level Optical Device for Monitoring Receptor–Analyte Interactions Without Functionalization Steps: A Case Study of Cytokine Detection by Nunzio Cennamo, Francesco Arcadio, Chiara Marzano, Rosalba Pitruzzella, Mimimorena Seggio, Maria Pesavento, Stefano Toldo, Antonio Abbate, Luigi Zeni

“…The POF-based device was proven to be effective for detecting several interleukins at the attomolar level in a few minutes and without functionalization processes.…”
Get full text

Unlocking the prebiotic carbohydrates: Insights into the types, preparation, health benefits and future utilizations of selected Indonesian exotic fruit seeds as a potential source... by Andri Cahyo Kumoro, Dyah Hesti Wardhani, Tutuk Djoko Kusworo, Yusuf Ma'rifat Fajar Azis, Misbahudin Alhanif, Tan Chin Ping

“…This paper aims to explore the feasibility of utilizing Indonesian exotic fruit seeds as a potential source of prebiotic carbohydrates for functional foods and dietary additives. …”
Get full text

Acoustic Fabry–Perot Resonance Detector for Passive Acoustic Thermometry and Sound Source Localization by Yan Yue, Zhifei Dong, Zhi-mei Qi

“…Acoustic temperature measurement (ATM) and sound source localization (SSL) are two important applications of acoustic sensors. …”
Get full text

Analytical Model and Gas Leak Source Localization Based on Acoustic Emission for Cylindrical Storage by Jun-Gill Kang, Kwang Bok Kim, Kyung Hwan Koh, Bong Ki Kim

“…A theoretical model is presented for the accurate detection of a gas leak source through a pinhole in a cylindrical storage vessel using the acoustic emission (AE) technique. …”
Get full text

A review of non-exhaust emissions on pavement area: Sources, compositions, evaluation and mitigation by Chuan He, Wei Jiang, Qingyi Xiao, Chengwei Xing, Dongdong Yuan, Rong Lu, Wangjie Wu

“…Non-exhaust particles can be classified into organic, inorganic, and metal matter, each requiring a distinct analysis and detection method. The effective approaches to managing non-exhaust emissions include water cleaning, utilizing functional pavement materials, and applying chemical reagents to alleviate emission capacity. …”
Get full text

Teucrium polium L.: A natural source of antioxidants and a potential UV protector. by Sarra Lamari, Ahmed Dekak, Sameh Boukhedir, Chawki Bensouici, Tarek Hamel, Imededdine Kadi

“…These results show that T. polium is a promising source for pharmaceutical applications (sunscreens, antioxidant supplements), pending further studies on its pharmacokinetic profile and potential drug interactions. …”
Get full text

Systematic investigation of photon strength functions with monochromatic γ-ray beams by Gheorghe Ioana, Aumann Thomas, Baumann Martin, van Beek Patrick, Kuchenbrod Philipp, Lalić Nikolina, Scheit Heiko, Symochko Dmytro, Wang Hongwei, Fan Gongtao, Nishio Katsuhisa, Ohtsuki Tsutomu, Suzaki Fumi, Hirose Kentaro, Inagaki Makoto, Ari-izumi Takashi, Garrote Frank L. Bello, Bjørøen Marianne, Eriksen Tomas, Ingeberg Vetle Wegner, Paulsen Wanja, Pedersen Line G., Reaz Fardous, Belyshev Sergey, Stopani Konstantin, Lui Yiu-Wing, Filipescu Dan, Tudora Anabella, Goriely Stephane, Miyamoto Shuji, Utsunomiya Hiroaki

“…Following the main objective of the IAEA Coordinated Research Project on Photonuclear Data and Photon Strength Functions (Code F41032; Duration 2016-2019), new measurements of photoneutron and photofission cross sections in the Giant Dipole Resonance energy region have been performed at the laser Compton-scattering γ-ray source of the NewSUBARU synchrotron radiation facility. …”
Get full text

Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells. by Xiaowen Chen, Joanna Tober, Martin Dominguez, Alan T Tang, Jenna Bockman, Jisheng Yang, Sneha Mani, Chin Nien Lee, Mei Chen, Triloshan Thillaikumaran, Patricia Mericko-Ishizuka, Monica Mainigi, Nancy A Speck, Mark L Kahn

Get full text

Estimating Finite Source Effects in Microlensing Events due to Free-Floating Planets with the Euclid Survey by Lindita Hamolli, Mimoza Hafizi, Francesco De Paolis, Achille A. Nucita

“…We find a significant efficiency for finite source effect detection that turns out to be between 20% and 40% for a FFP power law mass function index in the range [0.9, 1.6]. …”
Get full text