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521
PPI-GA: A Novel Clustering Algorithm to Identify Protein Complexes within Protein-Protein Interaction Networks Using Genetic Algorithm
Published 2021-01-01“…Any disturbance in proteins interactive network can act as a source for biological disorders and various diseases such as Alzheimer and cancer. …”
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522
Big data for imaging assessment in glaucoma
Published 2024-09-01“…Leveraging vast data sources, these technologies promise to enhance clinical practice and public health outcomes by enabling earlier disease detection, progression forecasting, and deeper understanding of underlying mechanisms. …”
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523
Glucose Sensing in Saliva
Published 2024-11-01“…Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. …”
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524
Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers
Published 2025-01-01“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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525
Sunlight Noise Mitigation in FMCW LiDAR Using FADOF
Published 2024-01-01“…Additionally, the system achieves a detection range of at least 17 meters under direct sunlight conditions. …”
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526
The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride.
Published 2014-01-01“…Here we analyzed the functions of the T. atroviride Ste12 transcription factor whose orthologue in yeast is targeted by the Fus3 and Kss1 MAP kinases. …”
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527
Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis
Published 2025-07-01“…IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. …”
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528
Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors
Published 2025-05-01“…Due to environmental factors, cross media propagation, and interference from excitation sources, noise is coupled into the original signal during data acquisition, seriously affecting signal processing. …”
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529
Chemometrically assisted optimization and validation of the HPLC method for the analysis of alectinib and its related impurity with measurement uncertainty evaluation and whiteness...
Published 2025-05-01“…This made it possible to find and measure the sources of uncertainty as well as the factors that affected the chromatographic responses. …”
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530
Role of Polyphosphate as an Inorganic Chaperone to Prevent Protein Aggregation Under Copper Stress in <i>Saccharolobus solfataricus</i>
Published 2024-12-01“…They are present across all life domains, serving as a source of energy, metal chelators, and playing a crucial role in stress defense. …”
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531
Species-level enumeration of low-concentration lactic acid bacteria in breast milk
Published 2025-12-01Get full text
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532
Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice
Published 2020-01-01“…Dental tissue has been acknowledged as an advantaged source for high-quality dental pulp stem cell (DPSC) preparation. …”
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533
The Roles of Transcrustal Magma- and Fluid-Conducting Faults in the Formation of Mineral Deposits
Published 2025-05-01“…At hydrocarbon fields, they play extremely important roles in conductive and convective heat, as well as in mass transfer to the area of hydrocarbon generation, determining the relationship between the processes of lithogenesis and tectogenesis, and activating the generation of hydrocarbons from oil and gas source rock. Detection of TCMFCFs was carried out using MMSS (the method of microseismic sounding) and MTSM (the magnetotelluric sounding method), in combination with other geological and geophysical data. …”
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534
SentemQC - A novel and cost-efficient method for quality assurance and quality control of high-resolution frequency sensor data in fresh waters [version 1; peer review: 1 approved,...
Published 2024-11-01“…SentemQC (QA-QC of high temporal resolution sensor data) is a cost-efficient, and open-source Python approach developed to ensure the quality of sensor data by performing data QA and QC on large volumes of high-frequency (HF) sensor data. …”
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535
Fast-timing spectroscopy with the ν-ball2 spectrometer
Published 2025-01-01“…In the first stage, the neutron beam was produced by the LICORNE source in an inverse kinematics reaction with a pulsed 7Li beam delivered by the Tandem accelerator, incident on an H2 gas cell. …”
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536
Multiwavelength Constraints on the Local Black Hole Occupation Fraction
Published 2024-01-01“…We also constrain the extremely low-luminosity end ( L _bol ≲ 10 ^40 erg s ^−1 ) of the active galactic nucleus (AGN) luminosity functions at z = 0. Our AGN luminosity functions are broadly consistent with an extrapolation of the shallow slope of the AGN luminosity functions from previous work.…”
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537
Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis
Published 2024-12-01“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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538
Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons
Published 2025-03-01“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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539
Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible
Published 2025-05-01“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
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540