Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome by Jun-Jie Li, Qing Yao, Ming Dong, Yan Wang, Ye Xiu, Zhi-Xin Wu, Xiao-Mei Zhao, Yin-Kang Wang, Xian-Ling Wang, Yu-Xuan Tian, Xiao-He Xiao, Zhao-Fang Bai

“…Materials and Methods: The activation of the cGAS-STING pathway was modeled in bone marrow-derived macrophages (BMDMs) and human leukemia monocytic cell line (THP-1) cells in vivo, and the expression of type I IFN-related genes and pro-inflammatory cytokines was detected after DG pretreatment. Next, we examined the effect of DG on STING downstream signaling events, such as STING oligomerization and functional STING signalosome formation. …”
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Correlation between D-dimer and size of middle cerebral artery infarction and its relation to functional outcome by Ramy Taha Alloush, Mohamed Hamdy Ibrahim, Shahinaz Mohamed Helmy, Aya Ebrahim Marwan, Mona Ali Eissa, Adel T. Alloush, Mohamed Khaled Elewa

“…Furthermore, data from neuroimaging, clinical, laboratory, and demographic sources were examined. Additionally, the modified Rankin Scale (mRS) score was used to evaluate the predictive usefulness of plasma D-dimer on a patient's functional outcome after three months. …”
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Molecular logic gates based on programmable self-assembly of DNA origami triangles for the detection of nucleic acid molecules by Si Sun, Jin-Da Wen, Qian-Ru Xiao, Xiao-Li Qiang, Xiao-Long Shi

“…Triangular DNA origami modules, designed with edge-specific hybridization sites, successfully emulate Boolean logic operations (YES, AND, and OR gates) to achieve target-driven hierarchical self-assembly. …”
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From intermediate capture to functional cluster construction: Synthesis of silver clusters and their Br−/I− sensing applications by Zhixun Zhang, Juefei Dai, Cheng-Cheng Feng, Chuanhua Shi, Lebing Zhou, Xianyong Yu, Chao Yang, Xueji Zhang, Huayan Yang

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Android malware detection via efficient application programming interface call sequences extraction and machine learning classifiers by Tanjie Wang, Yueshen Xu, Xinkui Zhao, Zhiping Jiang, Rui Li

“…In API call sequences extraction, we propose an algorithm for transforming the function call graph from a multigraph into a directed simple graph, which successfully avoids the unnecessary repetitive path searching. …”
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Designing an innovative, eco-conscious optode for spectrophoto-metric detection of copper across various biological and environmental samples by Abdullah H. Alluhayb, Alaa M. Younis, Alaa S. Amin, Naglaa Mohamed

“…An environmentally sustainable optode has been developed for the detection of copper ions in water-based solutions. …”
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Design of Potentiometric Sensor Based on Molecularly-imprinted Polymer for Direct Detection of Levofloxacin in Plasma for Point-of-Care Applications by Amr M. Mahmoud, Hanaa Saleh, Michael Gamal Fawzy, Alaa Reda, Eman A. Bahgat

“…The sensor was successfully employed for LVF assay in spiked plasma samples and pharmaceutical dosage form without any interference from any common additives or excipients. …”
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Pilot Study of Using Machine Learning to Detect Atherosclerotic Renal Artery Stenosis From Spectral Doppler Waveforms by Haseeb Mukhtar, Seyed Moein Rassoulinejad-Mousavi, Shahriar Faghani, Bradley J. Erickson, Sanjay Misra

“…Conclusion: ML has been successfully employed to detect ARAS using arterial spectral Doppler waveforms in DUS.…”
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Can Machine Learning Enhance Intrusion Detection to Safeguard Smart City Networks from Multi-Step Cyberattacks? by Jowaria Khan, Rana Elfakharany, Hiba Saleem, Mahira Pathan, Emaan Shahzad, Salam Dhou, Fadi Aloul

“…Smart cities rely on these systems seamlessly functioning with one another, and any successful cyberattack could have devastating effects, including large-scale data theft. …”
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BASSET: Bandpass-adaptive Single-pulse Search Toolkit—Optimized Subband Pulse Search Strategies for Faint Narrowband Fast Radio Bursts by J. H Cao, P. Wang, D. Li, Q. H. Pan, K. Mao, C. H. Niu, Y. K. Zhang, Q. Y. Qu, W. J. Lu, J. S. Zhang, Y. H. Zhu, Y. D. Wang, H. X. Chen, X. L. Chen, J. H. Fang, Y. Feng, H. Gao, Y. F. Huang, J. Li, C. C. Miao, C. W. Tsai, J. M. Yao, S. P. You, R. S. Zhao, Q. Z. Liu, S. M. Weng, S. H. Yew, J. Zhang, L. Zhang, E. Gügercinoğlu, D. K. Zhou, W. W. Zhu

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Proof-of-concept MALDI-TOF-MS assay for the detection of Toxin B enzymatic activity in Clostridioides difficile infection by Josef Dvorak, Lukáš Fojtík, Ljubina Adámková, Katerina Vlkova, Vendula Studentova, Katerina Chudejova, Lenka Geigerová, Michael Volny, Petr Novak, Jaroslav Hrabak, Petr Pompach

“…The assay was successfully tested for the detection of Toxin B in a cohort of patient samples as well as in cell culture of C. difficile.IMPORTANCEThe diagnostics of Clostridioides difficile infection is usually based on the identification of the bacterial pathogen and/or on the detection of the Toxins A and B. …”
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Electrochemical Sensor for Cu(II) Based on Carbon Nanotubes Functionalized with a Rationally Designed Schiff Base by Alejandro Tamborelli, Michael López Mujica, Gustavo Servetti, Diego Venegas-Yazigi, Patricio Hermosilla-Ibáñez, Pablo Dalmasso, Gustavo Rivas

“…This work proposes a new strategy for the electrochemical quantification of Cu(II) using glassy carbon electrodes (GCEs) modified with a nanohybrid of multiwall carbon nanotubes (MWCNTs) non-covalently functionalized with a rationally designed Schiff base containing different groups (SB-dBA). …”
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Fracture maturity controls the complexity of earthquake rupture: evidence from source processes of six moderate earthquakes during swarm activities off the east coast of Izu Penins... by Yukako Tanaka, Takuji Yamada

“…We first selected waveforms of smaller earthquakes (Mw3.4–3.9) as empirical Green’s functions and carried out the waveform inversion with 200 time windows for two horizontal components of 10-s-long K-net waveforms. …”
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Pollination-driven modulation of amino acid biosynthesis in plum: A multi-omics approach by Lijun Deng, Binshu Yuan, Xiaojun Jin, Yingying Xu, Yuhuan Feng, Xuan Zhang, Hui Zhang, Bo Xiong, Xun Wang, Guochao Sun, Mingfei Zhang, Siya He, Ling Liao, Zhihui Wang

“…The findings underscore the potential to improve the nutritional value of plums through the strategic selection of pollination cultivars. In addition, this research provides a foundation for a deeper understanding of the regulatory mechanisms underlying amino acid biosynthesis in plum and supports the development of relevant functional foods.…”
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The ANFIS-RSM based multi-objective optimization and modelling of ultrasound-assisted extraction of polyphenols from jamun fruit (Syzygium cumini) by Mohammad Ganje, Somayyeh Gharibi, Fatemeh Nejatpour, Maryam Deilamipour, Kimia Goshadehrou, Sahra Saberyan, Gholamreza Abdi

“…For each of the six process-solver conditions, optimal ANFIS models were determined by analyzing the number and type of input membership functions, the output membership function, and the selected optimization and defuzzification methods, based on the highest correlation between actual and predicted data, along with the lowest error rates. …”
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Time-domain brain: temporal mechanisms for brain functions using time-delay nets, holographic processes, radio communications, and emergent oscillatory sequences by Janet M. Baker, Peter Cariani

“…A temporal theory for realizing major brain functions (e.g., sensation, cognition, motivation, attention, memory, learning, and motor action) is proposed that uses temporal codes, time-domain neural networks, correlation-based binding processes and signal dynamics. …”
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A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles by Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger

“…Subsequently, adding gold nanoparticles functionalized with SERS probes and aptamers enabled the detection of tau in EVs using SERS. …”
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Zwitterionic Poly(sulfobetaine methacrylate) Brushes Functionalized Threads for DNA Extraction from Complex Cell Lysates by Xianlong Shi, Liang Wu, Ke Ning, Xinmei Li, Lingke Feng, Yirong Chen, Ling Yu

“…Characterization using SEM, FTIR, and EDS confirmed the successful functionalization with PSBMA polymer brushes. …”
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Curcumin Combined with Aerobic Exercise Improved Liver Function in Rats with Non-alcoholic Fatty Liver Disease by HU Ge, QIN Fei, CAO Jianmin, JI Zhe, ZHOU Qiyun, ZHOU Haitao

“…Results: NAFLD was successfully induced after eight weeks of a high-fat diet. …”
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Phenotype and function of human monocytes remain mainly unaffected by very small superparamagnetic iron oxide particles by Sari Hussein, Sari Hussein, Anja Andrea Kühl, Laura Golusda, Laura Golusda, Christina Plattner, Nadine Heinze, Nadine Heinze, Gregor Sturm, Christian Freise, Heike Traub, Mathias Schannor, Zlatko Trajanoski, Matthias Taupitz, Britta Siegmund, Daniela Paclik, Daniela Paclik

“…We have developed in-house very small superparamagnetic iron oxide nanoparticles (VSOP), 7 nm in size, which have been successfully used in preclinical magnetic resonance imaging (MRI) to detect intestinal inflammation, neuroinflammation and atherosclerosis. …”
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